Technology Description: UC San Diego inventors have invented a very general method to design and create new compounds with anti-bacterial, anti-fungal, anti-cancer, or other bioactive properties. Different from the existing art, where the biological effect of a compound must be determined, this invention allows for compounds to be designed and created with these effects known a priori. For example, this shortcoming, which the current invention overcomes, is part of the existing art being applied to anti-bacterial synthesis—such as mutational biosynthesis, genetic engineering, structure-based drug design, or interrogation of novel natural products.
State of Development: Experimental work to create a positive bioassay has been completed and the invention is already being applied to the creation of novel anti-bacterial agents.
Keywords: bioinformatics, novel compound design
Case Number: SD2008-230
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