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Researchers at the University of California, San Diego, have developed a novel approach to improving S/N of NMR and MRI data that replaces time consuming (hours or days) signal averaging on expensive instruments, with calculations that can be performed rapidly (seconds or minutes) on personal computers. Many biological samples degrade during the signal averaging process, and this method reduces this source of error and expense.
The method has been demonstrated to work on several experimental data sets from both one and two dimensional experiments on single crystal test compounds and a protein. The results of conventional signal averaging and the new method have been compared directly and shown to give the same results, except that much less time was required utilizing the new method. This approach may also have applicability to other forms of spectroscopy. While this method is in early-stage development, licensing opportunities are presently available.
Case No: SD2005-125
Inquiries To: invent@ucsd.edu
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