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BACKGROUND: Full
realization of the potential of many transgenes depends
on selective expression in tissues of interest. The
following describes a plant promoter isolated from Arabidopsis
thaliana that is operative only in the dehiscence zone
tissues of plants, and is suitable for driving the expression
of genes desired to operate only in this tissue.
DESCRIPTION: A
promoter has been isolated from Arabidopsis which upregulates
transferred gene expression only in the dehiscence zone
on the valve margins, and in no others, when placed
upstream of a transgene in a construct of interest.
The promoter can also be used to identify and recover
orthologues in plant species of interest.
ADVANTAGES: This
promoter may have value in the expression of genes intended
to control seed pod shatter
STAGE OF DEVELOPMENT:
Dehiscence zone-specific expression driven by this promoter
has now been demonstrated in one species other than
Arabidopsis.
Case Number: 2000-009
INQUIRIES TO: invent@ucsd.edu
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