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BACKGROUND: Full realization of
the potential of many transgenes depends on selective
expression in tissues of interest. The following describes
a plant promoter isolated from Arabidopsis thaliana
that is operative only in the epidermal tissues of plants,
and is suitable for driving the expression of genes
desired to operate only in this tissue.
DESCRIPTION: A promoter has been
isolated from Arabidopsis which upregulates transferred
gene expression only in epidermal tissues, and in no
others, when placed upstream of a transgene in a construct
of interest. The promoter can also be used to identify
and recover orthologues in plant species of interest.
ADVANTAGES: There are several
instances in which selective epidermal expression of
foreign genes could prove useful, including: pest resistance,
pigmentation, fragrance, wax synthesis, water metabolism
or energy metabolism.
STAGE OF DEVELOPMENT: Epidermal-specific
expression driven by this promoter has now been demonstrated
in species other than Arabidopsis.
CASE NUMBER: SD99-088
INQUIRIES TO: invent@ucsd.edu
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