Biomedical Technologies
These technologies include (but are not limited to):
Individual technology cases are listed below for review, or you may search via keywords using the search feature at the top of the menu bar.
- New Ras Inhibiting Compounds (SD2012-020)
- Novel Compositions for Cancer Therapy (Proteasomes Inhibitors) (SD2011-354)
- Use of PAK Inhibitors as Cancer Therapeutics and Biomarkers for Prognosis and Monitoring (SD2011-351)
- Molecular Mechanisms of Hepatocellular Carcinogenesis, Diagnosis, and Treatment (SD2011-346)
- Biological “Cloaking” of Nanoparticles for Cancer Drug Delivery (SD2011-343)
- A Restriction Spectrum Imaging Method and Device for Probing Tissue Microstructure (SD2011-311)
- Transmission of Endoplasmic Reticulum Stress from Tumor Cells to Myeloid Cells (SD2011-280)
- Attenuate Inflammation from Sunburn or Other Forms of Radiation (SD2011-226)
- New Compound that Stimulates Immune Cells to Eliminate Cancers (SD2011-202)
- Diagnostic and Therapeutic Particles with Decreased Cavitation Threshold: Payload Released by Focused Ultrasound (SD2011-148)
- A Novel and Sensitive Method for Cancer Diagnosis and Monitoring (SD2011-079)
- A Marker and Therapeutic Target for the PI3K Pathway (SD2011-066)
- A Novel Dynamic Shielding Applicator for High Dose Rate Brachytherapy (SD2011-056)
- Use of MicroRNAs and MicroRNA Inhibitors to Modulate Blood Vessel and Neuronal Growth, Patterning, Tumor Growth, and Malignant Disease (SD2011-032)
- Biomarker for Efficacy of Allosteric RAF Inhibitors (SD2011-015)
- A Potent Peptide Adjuvant for Vaccines and Immunotherapies (SD2011-014)
- A Gene Delivery System to Express and Evaluate HCV Proteins in Mice (SD2010-354)
- Marine Natural Products(SD2010-351)
- Receptor Tyrosine Kinase-Like Orphan Receptor 1 (ROR1) Single Chain FV Antibody Fragment Conjugates and Methods of Use (SD2010-306)
- Fast GPU-Based Aperture Optimization for Online Adaptive Radiotherapy Treatment Planning (SD2010-288)
- A Novel High-Efficiency Algorithm for Optimizing Volumetric Modulated Arc Therapy (VMAT) Radiotherapy Treatment Planning (SD2010-287)
- A Novel Anti-Cancer/Anti-Proliferation and Anti-Migration Compound—An Inhibitor to Dual Specificity Phosphatase Slingshot-2 (SD2010-247)
- Stimulus-Triggered Metalloenzyme Inhibitors (SD2010-123)
- Identification of Liver-Cancer Initiating Cells and a Method to Inhibit Their Tumorigenic Potential (SD2010-115)
- Therapeutics and Biomarkers Based in Kinase (RON RTK)/Growth Factor (IGF1-R) Crosstalk (SD2010-065)
- Pro-Drug Conjugates Able to Deliver Precise Ratios of Active Drugs (SD2009-349)
- Novel Method for the Prevention and Treatment of Cancer Metastasis Dissemination (SD2009-291)
- Targeting Integrin for the Intervention of Tumor Growth and Metastasis (SD2009-201)
- Methods to Inhibit Angiogenesis, Lymphogenesis, Hematopoetic Differentiation, and Metastasis (SD2009-201b)
- Compositions and Methods for Determining Cancer Stem Cell Self-Renewal Potential (SD2009-187 and SD2009-192)
- Targeting B Cells in Prostate Cancer (SD2009-172)
- A Method to Diagnose the Risk for and Prevent Breast Inflammation and Breast Cancer (SD2009-163 and SD2010-179)
- Protein Biomarkers for Diagnosis and Treatment of Chronic Lymphocytic Leukemia (CLL) (SD2009-033)
- Nanoparticles for Targeted, In Vivo Delivery of Diverse Drug Chemotypes (2009-032)
- Novel Amide Derivatives of Ethacrynic Acid for Cancer Therapy (SD2008-316)
- A Method of Developing Single Molecule DNA Nanoparticles as Diagnostic and
Therapeutic Agents (SD2008-237) - Potential Treatment for Breast Cancer With Peptides/Peptidomemetics/Small Molecules of a Defined Region of BRCA1 that Induce Apoptosis (SD2008-132)
- New Drug Treatment for Large B-Cell Lymphomas or Other Hematopoietic Malignancies (SD2008-071)
- Cancer Therapy Method (SD2008-018)
- Comprehensive Pharmacogenetic Approach to the Diagnosis and Treatment of Cancer (cancer bundle/SD2007-cancer)
- Unique Compound Inhibits Angiogenesis in Cancer and Eye Diseases (SD2007-225)
- Methods to Inhibit the Emergence or Progression of Hepatocellular Carcinoma with Estrogens or Estrogen Like Compounds (SD2007-190)
- Methods to Make the Early Detection of Hepatocellular Carcinoma; Methods to Inhibit the Emergence or Progression of Hepatocellular Carcinoma (SD2007-189)
- Methods to Inhibit the Emergence of Metastatic Prostate Cancer (SD2007-141)
- Generation and Modulation of Cancer Stem Cells (SD2007-099)
- In Vivo Screen for Agents Affecting Erythroid Development and Disease (SD2007-090)
- New Derivatives of Pyrone, Hydroxypyridinone, and Hydroxypyridinethione (SD2007-058)
- The Integrin Activation Interface (SD2007-053)
- Oral Drug for Stimulation of Erythropoietin Levels in Anemic Patients (SD2006-267)
- Methods for High Sensitivity Detection of Deletions from Genomic DNA (SD2006-249)
- A Novel Method to Inhibit Lymphangiogenesis and Tumor Metastasis(SD2006-143)
- pH-"Tunable" Nano-Particle Drug Delivery System (SD2006-140)
- Compositions and Methods for Therapeutic Cancer Vaccines (SD2006-095)
- Self-Adjuvanting Viral, Bacterial, Parasitic, and Tumor Vaccines (SD2006-025)
- Natural Products for Cancer Therapeutics (SD2006-079)
- Polyamine Ligands for Use as Metalloproteinase Inhibitors (SD2006-069)
- Novel Markers for the Treatment and Diagnosis of Chronic Lumphocytic Leukemia (CLL) (SD2006-052)
- Compositions and Methods to Enhance the Immune Response (SD2005-252)
- Tbx Genes Regulate Cell Cycle Partially Through Control of N-Myc Transcription (SD2005-223)
- Methods for Treating Chronic Lymphocytic Leukemia (CLL) by Regulating Cell Survival (SD2005-221)
- Treatment and Diagnosis of Chronic Lymphocytic Leukemia (CLL), Breast Cancer, and Other Cancers Through Use of a Monoclonal Antibody (SD2005-212)
- Method for Generating Unlimited Numbers of Macrophage/Dendritic Cells and Neutrophils (SD2005-114)
- New Activity of HSP90 Inhibitors Inducing Down Regulation of ZAP-70 and Inducing Apoptosis in Leukemia Cells (SD2005-094)
- Method of Increasing Efficacy of Tumor-Cell Killing Using Combinations of Anti-Neoplastic Agent (SD2005-062)
- Irofulven and Novel Derivatives for Cancer Treatment (SD2005-D37)
- Apoptosis Inhibitors (SD2005-E50)
- Treatment for Type II Diabetes and Cancer by Regulating Glucose Transporter Levels (SD2004-243)
- Superactive p53 (SD2004-160)
- Mice Lacking IKK Beta in Intestinal Epithelial Cells (SD2004-133)
- Novel Matrix Metalloproteinase Inhibitors (SD2004-102)
- In Vivo Propagated Murine A20 Lymphoma Cells (SD2004-085)
- Novel Method to Inhibit Tumor Growth and Other Neovascular Diseases (SD2004-076)
- Oligonucleotides for the Treatment of Cancer and Autoimmune Diseases (SD2004-013)
- Regulating Genes in the COX-2 Pathway for Colon Cancer (SD2003-261)
- Marine Organism Yields a Patented Family of Antitumor/Antibiotic Compounds (SD2003-248)
- Novel Therapeutic Approach for Cancer, Fibrosis, and Auto-Immune Disorders (SD2002-149)
- Targeted Cancer Therapy (SD2002-020)
- A Novel Method to Detect and Inhibit Angiogenesis (SD2001-135)
- Treatment of Cancer by Inducing Cell Apoptosis (SD2001-030)
- Wnt and Frizzled Receptors as Targets of Immunotherapy in Human Cancers (SD2001-C78)
- ISS-Receptor as a Drug Discovery Tool (SD2000-C22)
- A New Strategy for Leukemia Therapy (SD2000-159)
- Novel Antigen for Immunization in Cancer (SD2000-051)
- Disease Treatments Using Multimeric TNFSF Ligands (SD1999-003)
- Etodolac for the Prevention and Treatment of Prostate Cancer (SD1999-C38)
- A Method to Induce CTL Response in Immune Deficient Patients (SD1999-A77)
- Diagnosis of Cancers with Metastatic Potential (SD1998-D00)
- Vaccines with Enhanced Intracellular Processing (SD1997-065)
- Prosaposin: Therapeutic Compound for Prevention and Treatment of Pain (SD1996-043)
- Diagnostic Test for Cancer Susceptibility (SD1994-A91)
- Transcription Factor for the Regulation of Skin and Hair Development (SD1993-A27)
- Method for Selective Methionine Starvation of Malignant Cells (SD1992-C83)
- Prognostic and Diagnostic Serum Biomarker for Cancer and Inflammatory Disease (SD1992-C06 and SD1998-C98)
- A Novel Method for Diagnosing Retinoblastoma (RB) and Retinoblastoma Gene Involved Cancers (SD1987-C03)
Therapeutic Areas - Cardiovascular Diseases
- Systemic Delivery and Regulated Expression of Paracrine Genes for Cardiovascular Diseases and Other Conditions (SD2012-210)
- Development of Diagnostics and High Throughput Screens to Detect and Treat Cardiac Hypertrophy Caused by Elevated Levels of DSCAM and COL6 (SD2012-169)
- Peptide-Albumin Conjugates (SD2012-089)
- Extracellular Matrices and Methods for Treating Peripheral Artery Disease (PAD) (SD2012-053)
- Biological “Cloaking” of Nanoparticles for Cancer Drug Delivery (SD2011-343)
- Effects of Long-term Use of Statins (SD2011-288)
- Therapy for Hypertension and the Metabolic Syndrome (SD2011-273)
- Novel Biomarker and Therapeutic Target for Cardiomyopathy and Congestive Heart Failure (SD2011-107)
- Stimulus-Triggered Metalloenzyme Inhibitors (SD2010-123)
- Monitoring Atherosclerosis Regression, Plaque Stabilization, and Cardiovascular Risk Using a Novel Method to Quantify Oxidized Phospholipids (SD2009-236)
- Protein Biomarkers for Kawasaki Disease (SD2009-047)
- Novel Methods to Predict New Cardiovascular Events by Measuring Oxidized Phospholipids (OxPL), Lipoprotein (a) and Lipoprotein-Associated Phospholipase A2 Mass and Activity (Lp-PLA2) and Novel High-Throughput Assay to Quantitate Lp-PLA2 on Lipoprotein (a) and Apolipprotein B-100 Particles to Determine Cardiovascular Risk (SD2007-261)
- Markers for Cardiac Conduction Tissue (SD2007-203)
- A Novel Nitric-Oxide Releasing Drug (SD2007-196)
- Cardioprotective Effects of Catestatin (SD2007-118)
- New Derivatives of Pyrone, Hydroxypyridinone, and Hydroxypyridinethione (SD2007-058)
- The Integrin Activation Interface (SD2007-053)
- Atheroprotective Vaccine (SD2006-250)
- Assay for Small Molecules and Defined Factors to Trigger Renewal of Cardiac Progenitors (SD2006-211)
- New Target for Cardiovascular Disease and Diabetes (SD2005-165)
- Enhanced Expression of TRP Channels in Idiopathic Pulmonary Arterial Hypertension (IPAH) (SD2005-073)
- A Novel Index of Assessing Atherosclerosis Regression and Plaque Stabilization (SD2005-037)
- Novel Matrix Metalloproteinase Inhibitors (SD2004-102)
- Method for Generating a Progenitor Population from Postnatal Hearts (SD2003-140)
- Non-Invasive, Sensitive Diagnostic for Viral Myocarditis (SD2003-099)
- Use of Calcium Binding Proteins to Improve Cardiac Contractile Function. (SD2002-225)
- Novel Single Nucleotide Polymorphisms (SNPs) Associated with Hypertension (SD2001-215)
- ISS-Receptor as a Drug Discovery Tool (SD2000-C22)
- Method to Quantitate Oxidized LDL Epitope Content (SD2000-062)
- Assessing Risk for Arterial Calcification (SD1999-C79)
- Novel Recombinant Adenovirus Vectors for Tissue-Specific Gene Expression in Heart (SD1998-045)
- Novel Methods for Increasing Peripheral Blood Circulation (SD1997-098)
- Cryopreservation of Human Adult and Fetal Pancreatic Cells and Human Platelets (SD1997-A22)
Therapeutic Areas - CNS Diseases
- A Tool for Finding Drugs for Treating Neurodegenerative Diseases in the Brain (2012-170)
- Antipurinergic Therapy of Autism and Related Spectrum Disorders (SD2012-158)
- Efficient Method of Mapping Sources of Abnormal Routes of Vascular Circulation Regardless of Their Location Using MRI (SD2011-314 and SD2007-238)
- A Novel Method to Increase the Perfusion Signal to Noise Ratio (SNR) in Velocity Selective Arterial Spin Labeling for MRI (SD2011-312)
- Biomarkers and Genetic Tests for Autism and Other Developmental Disorders (SD2011-277)
- Brain Extracellular Matrix Compositions and Methods (SD2011-253)
- Automated System for High Throughput Screening in Rodents (SD2011-207)
- Personalized Treatment of Schizophrenia and Related Disorders with Selective Agonists and Antagonists of VPAC2R (2011-199)
- Alzheimer’s Disease Cellular Model for Diagnostic and Therapeutic Development Methods (SD2011-152)
- Dopamine D3 Binding Compounds With Subtype And Functional Selectivity (SD2011-141)
- Chemical and Genetic Mechanisms to Remove Misfolded Proteins from Human Cells (SD2011-098)
- Oxytocin for the Treatment of Schizophrenia (SD2011-017)
- Marine Natural Products(SD2010-351)
- New Early Diagnostic Test for Autism (SD2010-252)
- A Novel Anti-Cancer/Anti-Proliferation and Anti-Migration Compound—An Inhibitor to Dual Specificity Phosphatase Slingshot-2 (SD2010-247)
- Novel Gamma-Secretase Modulators for the Treatment of Alzheimer's Disease and Related Neurodegenerative Disorders (SD2010-246)
- Methods of Treating and Preventing Neurological Disorders Using Docosahexaenoic Acid (SD2010-201)
- Neuronal Specific Targeting of Caveolin Expression (SD2010-117)
- Selective Phospholipase A2 Inhibitors of Neurological Diseases (SD2009-298)
- Non-Invasive Physiological Manipulations of the Brain for Neurological Disorders (SD2009-178)
- Peptides Targeted to the CNS for Clearance of Protein Aggregates in Alzheimer's Disease (SD2009-058)
- Amide Inhibitors of Human Secreted Phospholipase A2 (SD2009-002)
- New Molecular Technique for Neural Tracing (SD2008-166)
- Transplantation of Human Neural Cells for Treatment of Neurodegenerative Conditions (SD2008-210)
- Non-Invasive Method for Diagnosing and Monitoring Alzheimer's Disease (SD2008-059)
- HESA: Hepatic Encephalopathy Screening Algorithm (SD2007-804)
- A Method to Measure Neurotransmitters In Vivo (SD2007-283)
- Promotion of Central Nervous System Neuronal Survival (SD2007-220a)
- Regeneration of Central Nervous System Axons After Trauma (SD2007-220b)
- Method for High-Resolution MRI-Based Magnetoencephalography (MR-MEG) (SD2007-035)
- Compounds Targeting ß-Amyloid Ion Channels for Diagnosis and Treatment of Alzheimer’s Disease (SD2007-018, SD2007-056)
- Development of a Specific Inhibitor for PDE4A4: Therapeutic Implications in Pulmonary Disease and Nerve Regeneration (SD2006-245)
- Lead Compounds for Diagnosis and Therapy of Alzheimer's Disease (SD2006-105)
- A Novel Method to Diagnose, Predict Treatment Response, and Develop Treatments for Psychiatric Disorders Using Biomarkers (SD2006-073)
- Method to Predict Treatment Response in Generalized Social Phobia (SD2006-021)
- Enhancing Neural Recovery Following Stroke or Brain Injury (SD2006-019)
- New Method for Promoting Nerve Regeneration (SD2005-155)
- Treatment for Mental Illness Through Manipulation of Neurotransmitter Profile (SD2004-218)
- Novel Therapeutic Approach for the Treatment of Autism Spectrum Disorders (SD2004-215)
- Gene Therapy for Usher Syndrome Type 1B (SD2004-074)
- NoScar ThinFilm: A Biocompatible Polymer Film for Post-Surgical Scar Reduction (SD2004-028)
- Phosphatases that Regulate Gene Transcription (SD2003-061)
- Laser-Based Method to Induce and Image Cortical Microstrokes In-Vivo for Preclinical Analyses (SD2003-021)
- Alzheimer's Vaccine (SD2002-161)
- Novel Anti-Inflammatory Inhibitors of Phospholipase A2 (SD2002-133)
- Use of Neurotrophic Factors in Treating Memory Loss and Neurodegenerative Disease (SD2001-109)
- Erythropoietin and Erythropoietin Receptors in the Peripheral Nervous System (SD2001-090)
- ISS-Receptor as a Drug Discovery Tool (SD2000-C22)
- Gene Targets for Neuropsychiatric Disorders (SD2000-094)
- Human Methods and Use of CNS Cell Lines (SD1998-A34)
- Prosaposin: Therapeutic Compound for Prevention and Treatment of Pain (SD1996-043)
- Regulatable Retrovirus System for Genetic Modification of Cells (SD1996-B05)
- Method for Production of Neuroblasts (SD1992-B16)
Therapeutic Areas - Dermatological, Ophthalmological, Otological Diseases
- New Matrices for Cosmetic and Reconstructive Surgery (SD2010-143)
- Attenuate Inflammation from Sunburn or Other Forms of Radiation (SD2011-226)
- Method for Non-Invasive Serial Profiling of Patients for Diagnostic, Forensic, and Pharmacogenomic Studies (SD2011-123)
- Firmocidin,TM A New Small-Molecule Antibiotic to Treat MRSA, Staph, and Streptococcus Infections (SD2011-030)
- Nano-Wire Based Retinal Implants (SD2010-348)
- Fluorescent Amyloid Binding Agents for Diagnosis of Alzheimer’s Disease (SD2010-162)
- A New Method to Accelerate Tissue and Wound Healing Rates and Reduce Swelling and Scar Formation (2010-084)
- Peptide Mimics of BOTOX® Cosmeceutical Action (SD2009-225)
- TNF-Alpha Inhibitor to Suppress Inflammation Without Suppressing the Innate Immune Response (SD2008-129)
- pH-"Tunable" Nano-particle Drug Delivery System (SD2006-140)
- Mouse Model for Macular Degeneration (SD2005-163)
- Antiviral, Anti-inflammatory, and Antimicrobial Peptides and Antimicrobial Peptide Enhancing Factor (SD2004-043, SD2003-114, and SD2003-079)
- Lipids for Local Eye Therapy for Diseases (SD2003-113)
- Broad Spectrum Natural Protein Antibiotic (SD2002-119)
Therapeutic Areas - Endocrine / GI Diseases
- A Tool for Finding Novel Agonists and Antagonists of ERα and ERβ (SD2012-156)
- New Therapeutic and Diagnostic Approaches for Liver Fibrosis (SD2011-295)
- Therapy for Hypertension and the Metabolic Syndrome (SD2011-273)
- Oligosaccharide to Prevent Necrotizing Enterocolitis (SD2011-192)
- Novel Method for Accelerating Alimentary Tract Recovery in Post Abdominal Surgeries (SD2011-054)
- Pancreastatin, A Novel Peptide Regulator of Glucose and Lipid Metabolism (SD2010-026)
- Beta-Arrestin Biased GPCR Agonists for Inflammation and Metabolic Disease (SD2009-028)
- Improved Means to Treat Intestinal Nematode Diseases of Animals and Prevent Drug Resistance (SD2008-247)
- MitoNEET: A New Approach for Designing Diabetes Drugs (SD2008-040)
- Isolated PTPMT1 Protein Which Mediates Insulin Production (SD2005-243)
- Method of Using Cell-Surface Proteins to Detect and Image Islet Beta Cells (SD2005-224)
- Acid-Reactive Antibodies for Therapy and Research Applications (SD2005-142)
- Treatment for Type II Diabetes and Cancer by Regulating Glucose Transporter Levels (SD2004-243)
- Mouse Model of Crohn’s Disease and Method to Develop Specific Therapeutics (SD2004-154)
- DNA:GST-AtNOS1 Plasmid (SD2004-143)
- Treatment for Diabetic Cardiomyopathy (SD2004-071)
- Methods of Treating Gastrointestinal Inflammation (SD2004-B64)
- Novel, Validated Target for Type II Diabetes Drug Inhibitors (SD2003-238)
- Phosphatases that Regulate Gene Transcription (SD2003-061)
- Treatment of Liver Fibrosis by Induction of Stellate Cell Apoptosis (SD2001-024)
- Oligonucleotides for the Treatment of Inflammatory Bowel Disease (SD2000-C23)
- Cryopreservation of Human Adult and Fetal Pancreatic Cells and Human Platelets (SD1997-A22)
- Prevention of Liver Fibrosis in Hepatitis by Inhibition of Stellate Cell Activation (SD1996-064)
- Prosaposin: Therapeutic Compound for Prevention and Treatment of Pain (SD1996-043)
Therapeutic Areas - Infectious Diseases
- New HCV Inhibitors (SD2012-254)
- Biological “Cloaking” of Nanoparticles for Cancer Drug Delivery (SD2011-343)
- Attenuate Inflammation from Sunburn or Other Forms of Radiation (SD2011-226)
- Agent to Treat and Prevent Amebiasis (SD2011-198)
- New Strategy for Treating Chronic Viral Infections (SD2011-173)
- New Delivery System for Anthelmintics for Animals and Humans (SD2011-091)
- Firmocidin,TM A New Small-Molecule Antibiotic to Treat MRSA, Staph, and Streptococcus Infections (SD2011-030)
- A Potent Peptide Adjuvant for Vaccines and Immunotherapies (SD2011-014)
- A Gene Delivery System to Express and Evaluate HCV Proteins in Mice (SD2010-354)
- General Method for Identifying Antimicrobial Compounds and Determining Antibiotic Sensitivity (SD2010-312)
- Phosphonates with Reduced Toxicity for Treatment of Viral Diseases (SD2010-158)
- Technologies for the Treatment of Viral Infections, Including Hepatitis C Virus (HCV) (SD2010-158b)
- Small Molecular Inhibitors of Hedgehog Protein Signaling for Treating or Protecting Against Influenza Infection (SD2010-150)
- Novel Inhibitors of Farnesyl Diphosphate Synthase and Undecaprenyl Pyrophosphate Synthase Used as Treatments for African Sleeping Sickness and Bacterial Infections (SD2009-315)
- Compositions and Methods for Activating Toll-Like Receptors (SD2009-057)
- Compositions and Methods for Preventing and Treating Anthrax Diseases (SD2009-056)
- Protein Biomarkers for Kawasaki Disease (SD2009-047)
- Improved Means to Treat Intestinal Nematode Diseases of Animals and Prevent Drug Resistance (SD2008-247)
- Method for Identifying A Bacterial Toxin and Strategy for Vaccine Development (SD2008-211)
- RNA ‘Friendly’ Ligands with Antiviral Activity for the Treatment of Hepatitis C (SD2008-145)
- Mitigating the Lethal Coagulopathy of Sepsis (SD2008-113)
- New Treatment for Anthrax Infection (SD2007-321)
- In Vivo Screen for Agents Affecting Erythroid Development and Disease (SD2007-090)
- Uncovering the Genetic Basis of Phenotypic Change (SD2007-024)
- Passive and Active Immunization/Vaccine for Hepatitis C Virus (SD2006-301)
- Oral Drug for Stimulation of Erythropoietin Levels in Anemic Patients (SD2006-267)
- Vaccination Platform for Persistent Viruses (SD2006-121)
- Polyamine Ligands for Use as Metalloproteinase Inhibitors (SD2006-069)
- Treatment of Intestinal Animal Parasitic Diseases in Veterinary and Human Medicine (SD2006-049)
- Self-Adjuvanting Viral, Bacterial, Parasitic, and Tumor Vaccines (SD2006-025)
- Acid-Reactive Antibodies for Therapy and Research Applications (SD2005-142)
- Derivatives of Novel Nucleoside Phosphonates with Anti-viral Activity (SD2005-105)
- A New Nucleoside Phosphonate Analog with Antiviral Activity (SD2004-257)
- Monoclonal Antibodies Immunoreactive with Lipolysaccharide Binding Protein (LBP) and Methods of Their Use (SD2004-221)
- Interference with the Virus-Induced CD4 Down-Modulation as an Anti-HIV Approach (SD2004-111)
- New Derivatives of Phosphonate Compounds with Enhanced Antiviral Activity. (SD2004-100)
- Marine Organism Yields a Patented Family of Antitumor/Antibiotic Compounds (SD2003-248)
- Polypeptide and DNA Immunization Against Coccidioides spp Infections: Immunogenic Antigens for a Vaccine for Coccidioidomycosis (SD2003-516)
- Use of MshC for Development of Tuberculosis Drugs and Vaccines (SD2002-094)
- Novel Compounds for the Development of TB Therapeutics (SD2001-169)
- ISS-Receptor as a Drug Discovery Tool (SD2000-C22)
- A Method to Induce CTL Response in Immune Deficient Patients (SD1999-A77)
Therapeutic Areas - Inflammation & Immune Diseases
- A Tool for Finding Drugs for Treating Neurodegenerative Diseases in the Brain (2012-170)
- Novel Application of AMP-activated Protein Kinase Activators for Suppression of Development and Progression of Osteoarthritis (SD2011-369)
- Diagnosis and Treatment of Arthritis Using Epigenetics (SD2011-318)
- A Biomimetic Method for Creating Transplantable Cartilage-Bone Grafts (SD2011-165)
- Anti-inflammatory Compounds Derived from Marine Natural Products (SD2010-329)
- Stimulus-Triggered Metalloenzyme Inhibitors (SD2010-123)
- Selective Phospholipase A2 Inhibitors of Neurological Diseases (SD2009-298)
- Methods to Inhibit Angiogenesis, Lymphogenesis, Hematopoetic Differentiation, and Metastasis (SD2009-201b)
- Beta-Arrestin Biased GPCR Agonists for Inflammation and Metabolic Disease (SD2009-028)
- Nanoparticles for Targeted, In Vivo Delivery of Diverse Drug Chemotypes (SD2009-032)
- New Use for Existing Drug to Treat Rheumatoid Arthritis, Lupus, or Other Autoimmune Diseases (SD2007-269)
- The Integrin Activation Interface (SD2007-053)
- Small Molecule Inhibitors of Alpha-4-Integrin-Paxillin Interaction (SD2007-009)
- Combination Therapy of Immunomodulatory Peptides and a Chloroquine Derivative to Treat Rheumatoid Arthritis and Other Autoimmune Disorders (SD2006-256)
- pH-"Tunable" Nano-particle Drug Delivery System (SD2006-140)
- Prevention and Treatment of Cytomegalovirus Infection Through Immunization with Novel CMV-Derived Peptides (SD2006-074)
- Compositions and Methods to Enhance the Immune Response (SD2005-252)
- Method for Generating Unlimited Numbers of Macrophage/Dendritic Cells and Neutrophils (SD2005-114)
- Lectin Type Fold as a Scaffold for Massive Sequence Variation (SD2005-108)
- Mouse Model of Crohn’s Disease and Method to Develop Specific Therapeutics (SD2004-154)
- Lysm-Cre/IKK Beta Loxlox Mice (SD2004-141)
- Villin-Cre/IKK Beta Loxlox Mice (SD2004-140)
- Mice Lacking IKK Beta in Intestinal Epithelial Cells (SD2004-133)
- Mice Lacking IKKß in Macrophages (SD2004-132)
- Mice with a Conditional IKK Beta Loss of Function (SD2004-131)
- Mice Lacking IKK Beta in Liver Cells - Models for Acute Hepatic Failure, Hepatocellular Carcinoma and Increased Sensitivity to Insulin (SD2004-130)
- IKK Beta Liver Knockout Cre Mice (SD2004-120)
- Novel Matrix Metalloproteinase Inhibitors (SD2004-102)
- Crossbred Mice: CK19 CRE X IKK Beta (Lox P) (SD2004-077)
- Novel Anti-Inflammatory Treatment by Blocking Signal Transduction Kinases in the Central Nervous System (SD2004-034)
- Methods of Treating Gastrointestinal Inflammation (SD2004-B64)
- Prevention of Pathogen-Induced Macrophage Apoptosis (SD2003-269)
- IKK Alpha (AA) Mice (SD2003-211)
- Reporters for the "Alternative" NF-kB Pathway (SD2003-196)
- Floxed IKKB Mice (SD2003-195)
- MEKK1 -/- Mice (SD2003-189)
- Dominant-Negative Kinase Adenoviral Construct for Arthritis (SD2002-169)
- P53 Knockout/DBA1 Mice as an Improved Model for Rheumatoid Arthritis (SD2002-132)
- Phase II Biologic to Treat Rheumatoid Arthritis and Other Autoimmune Diseases (SD2002-051, SD2001-901, SD2000-133, SD1999-268)
- A Method for Inhibiting B Cell Maturation and Antibody Production (SD2001-176)
- Novel Expression Vectors Containing Chimeric Ligand Genes Useful for Immunomodulation (SD2001-101, SD2001-102, SD2001-103, SD2001-104, SD2001-108)
- New Ligand Involved in the Transmigration of Leukocytes Across the Endothelium and Uses Therefor (SD2001-018)
- Mutations in IKKg Gene (SD2000-165)
- Oligonucleotides for the Treatment of Inflammatory Bowel Disease (SD2000-C23)
- ISS-Receptor as a Drug Discovery Tool (SD2000-C22)
- A Method to Inhibit I-Kappa-Beta Kinase, and Screen Drugs to Target Same (SD2000-015)
- A Method to Induce CTL Response in Immune Deficient Patients (SD1999-A77)
- Gamma-Subunit of Cytokine Responsive IkBa Kinase (IKK) Complex (SD1998-107)
- Prosaposin: Therapeutic Compound for Prevention and Treatment of Pain (SD1996-043)
- Phase II Biologic to Treat Rheumatoid Arthritis and Other Autoimmune Diseases (SD1993-268)
- Treatment of Disorders with Shortened Red-Blood Cell Survival (SD1993-B35)
- Prognostic and Diagnostic Serum Biomarker for Cancer and Inflammatory Disease (SD1992-C06 and SD1998-C98)
- Retrovirus Detection (SD1988-B08)
Therapeutic Areas - Respiratory Diseases
- Biological “Cloaking” of Nanoparticles for Cancer Drug Delivery (SD2011-343)
- New Method for Imaging Ventilation and Perfusion in the Lung Using MRI (SD2010-320)
- New Effective Low-cost Vaccines (SD2010-315)
- A MRI Arterial Spin Labeling Software for Quantification of Regional and Complete Pulmonary Blood Flow (SD2009-824)
- New Drug Derivatives for Promoting Oral Delivery to the Lung (SD2004-258)
Therapeutic Areas - Urological Diseases
- Synthetic Bone Grafts (SD2011-007)
- Marine Natural Products(SD2010-351)
- pH-Sensitive Stabilization of Liposomes (SD2010-249)
- Pancreastatin, A Novel Peptide Regulator of Glucose and Lipid Metabolism (SD2010-026)
- Induction of RNAi Responses by PTD-Mediated Cellular Delivery of Short Interfering RiboNucleic Basics (siRNBs) Containing Basic Protecting Groups (SD2009-323)
- Selective Phospholipase A2 Inhibitors of Neurological Diseases (SD2009-298)
- Enhanced Delivery Vehicle for Enzyme Replacement Therapy (SD2009-100)
- Chromatography for Diet and/or Nutrition/Chemical Control (SD2009-050)
- Genome-Scale Kinetic Models (SD2008-180)
- Uncovering the Genetic Basis of Phenotypic Change (SD2007-024)
- Genome-Scale Reconstruction of Human Metabolism (SD2006-294)
- Transducible Alpha Fragment Peptide B-gal Complementation (SD2006-270)
- Biosynthesis of Salinosporamide A and Analogs (SD2006-203)
- Multipotent Amniotic Fetal Stem Cells: A Novel Source of Human Stem Cells (SD2005-041)
- Therapy for septic shock (SD2004-263)
- Monoclonal Antibodies Immunoreactive with Lipolysaccharide Binding Protein (LBP) and Methods of Their Use (SD2004-221)
- Mice Lacking IKK Beta in Intestinal Epithelial Cells (SD2004-133)
- Clinical Trials Management System (SD2004-082)
- Gene Therapy for Usher Syndrome Type 1B (SD2004-074)
- Treatment for Smoke Inhalation and Cyanide Poisoning (SD2003-034b)
- New Treatment for Sepsis (SD2003-034)
- Transport Molecules from Dendritic Oligo-Guanidines (SD2002-042)
- Controlled Mineralization of a Matrix (SD2002-B28)
- A New Anti-Coagulant (SD2000-035)
- Disease Treatments Using Multimeric TNFSF Ligands (SD1999-003)
- Prosaposin: Therapeutic Compound for Prevention and Treatment of Pain (SD1996-043)
- Transcription Factor for the Regulation of Skin and Hair Development (SD1993-A27)
- Treatment of Disorders with Shortened Red Blood Cell Survival (SD1993-B35)
- Extracellular Matrices and Methods for Cardiac Repair, Arrhythmia Treatment, and Cardiac Cell Culture (SD2012-053)
- Brain Extracellular Matrix Compositions and Methods (SD2011-253)
- Defined and Xeno-free Media for Feeder Free Conditions for Maintenance of Human Induced Pluripotent Cells (iPSCs) and Embryonic Stem Cells (hESCs) (SD2010-299)
- Bacterial Artificial Chromosome Based Gene Targeting in Human ES Cells (SD2010-215)
- Neuronal Specific Targeting of Caveolin Expression (SD2010-117)
-
Scalable Generation of Erythrocytes from Embryonic Stem Cells and Progenitors Thereof (SD2010-045)
- Defined and Xeno-Free Serum Replacement for Maintenance of Human Embryonic Stem Cells or hESCs (SD2010-036)
- Compositions and Methods for Determining Cancer Stem Cell Self-Renewal Potential (SD2009-187 and SD2009-192)
- Programming Stem Cell Fate Using Designed Regulatory Proteins Without Genetic Modification (SD2008-311)
- Transplantation of Human Neural Cells for Treatment of Neurodegenerative Conditions (SD2008-210)
- Generation and Modulation of Cancer Stem Cells (SD2007-099)
- In Vivo Screen for Agents Affecting Erythroid Development and Disease (SD2007-090)
- Tbx Genes Regulate Cell Cycle Partially Through Control of N-Myc Transcription (SD2005-223)
- Multipotent Amniotic Fetal Stem Cells: A Novel Source of Human Stem Cells (SD2005-041)
- Method for Generating a Progenitor Population from Postnatal Hearts (SD2003-140)
New Chemical Entities, Drug Leads
- A Tool for Finding Drugs for Treating Neurodegenerative Diseases in the Brain (2012-170)
- A Tool for Finding Novel Agonists and Antagonists of ERα and ERβ (SD2012-156)
- Novel Compositions for Cancer Therapy (Proteasomes Inhibitors) (SD2011-354)
- Dopamine D3 Binding Compounds With Subtype And Functional Selectivity (SD2011-141)
- Firmocidin,TM A New Small-Molecule Antibiotic to Treat MRSA, Staph, and Streptococcus Infections (SD2011-030)
- Marine Natural Products(SD2010-351)
- Anti-inflammatory Compounds Derived from Marine Natural Products (SD2010-329)
- A Novel Anti-Cancer/Anti-Proliferation and Anti-Migration Compound—An Inhibitor to Dual Specificity Phosphatase Slingshot-2 (SD2010-247)
- Selective Phospholipase A2 Inhibitors of Neurological Diseases (SD2009-298)
- Analogs of the Cytotoxic Natural Product Mycolactone (SD2009-121)
- Amide Inhibitors of Human Secreted Phospholipase A2 (SD2009-002)
- Novel Amide Derivatives of Ethacrynic Acid for Cancer Therapy (SD2008-316)
- A New Antimitotic, Anticancer, and Antimicrobial Compound (SD2008-188)
- TNF-Alpha Inhibitor to Suppress Inflammation Without Suppessing the Innate Immune Response (SD2008-129)
- New Drug Treatment for Large B-Cell Lymphomas or Other Hematopoietic Malignancies (SD2008-071)
- Ultrasensitive, Ion Channel-Based Sensors (SD2008-006)
- Reagents for Ultrasensitive, Ion Channel-Based Detection and Quantization (SD2008-006_Reagents)
- Comprehensive Pharmacogenetic Approach to the Diagnosis and Treatment of Cancer (cancer bundle/SD2007-cancer)
- Compounds Targeting ß-Amyloid Ion Channels for Diagnosis and Treatment of Alzheimer’s Disease (SD2007-018, SD2007-056)
- Biosynthesis of Salinosporamide A and Analogs (SD2006-203)
- Lead Compounds for Diagnosis and Therapy of Alzheimer's Disease (SD2006-105)
- Natural Products for Cancer Therapeutics (SD2006-079)
- Irofulven and Novel Derivatives for Cancer Treatment (SD2005-D37)
- Apoptosis Inhibitors (SD2005-E50)
- Oligonucleotides for the Treatment of Cancer and Autoimmune Diseases (SD2004-013)
- Marine Organism Yields a Patented Family of Antitumor/Antibiotic Compounds (SD2003-248)
- Etodolac for the Prevention and Treatment of Prostate Cancer (SD1999-C38)
- Novel Anti-inflammatory Inhibitors of Phospholipase A2 (SD2002-133)
- Biological “Cloaking” of Nanoparticles for Cancer Drug Delivery (SD2011-343)
- Electric Field Assisted Biomolecule Transport, Capture, and Sensing in Carbonized, Porous Nanostructures (SD2011-322)
- Highly Efficient Catalytic Microtube Engines (SD2011-286)
- Porous Silicon Particles as Adjuvant to Modulate Immune Response and Deliver Antigens for Vaccination (SD2011-164)
- Diagnostic and Therapeutic Particles with Decreased Cavitation Threshold: Payload Released by Focused Ultrasound (SD2011-148)
- Nanoconjugate for RNA-Triggered Drug Delivery Platform (SD2011-064)
- pH-Sensitive Stabilization of Liposomes (SD2010-249)
- Polymeric Nano-Carriers with a Linear Dual Response Mechanism to Detect Disease (SD2010-189)
- Smart Materials Capable of Programmed Shape Change (SD2010-007)
- Pro-Drug Conjugates Able to Deliver Precise Ratios of Active Drugs (SD2009-349)
- Delivery of Therapeutically Relevant Macromolecules Using pH-Sensitive Peptide Transduction Linkages (SD2009-296)
- Biodegradable Luminescent Porous Silicon Nanoparticles for In Vivo Applications (SD2009-246)
- Transducible Delivery of Nucleic Acids Using Modified dsRNA Binding Domains (SD2009-213)
- Enhanced Delivery Vehicle for Enzyme Replacement Therapy (SD2009-100)
- Nanoparticles for Targeted, In Vivo Delivery of Diverse Drug Chemotypes (SD2009-032)
- Magnetic Iron Oxide Nanoworms for In Vivo Tumor Targeting (SD2008-327)
- Novel, On-Off Switchable, Drug Delivery Vehicles, FabricationTechniques and Applications Thereof (SD2008-144)
- Scalable, Inexpensive Method to Make Hollow Nanoparticles for Life Science Applications (SD2008-016)
- Spinal Multi-segmental Cell and Drug Delivery System (SD2007-267)
- Method for Manipulating and Heating of Discrete Droplets Using Magnetic Particles Derived from Porous Silicon (SD2006-176)
- pH-"Tunable" Nano-Particle Drug Delivery System (SD2006-140)
- Optimizing Expression of Recombinant Protein in Mammalian Cells (SD2005-186)
- New Method for Promoting Nerve Regeneration (SD2005-155)
- Biological Applications of "Smart Dust," or Porous Silicon Photonic Crystals (SD2005-038 and SD2005-044)
- New Drug Derivatives for Promoting Oral Delivery to the Lung (SD2004-258)
- Magnetic Navigation System for Diagnosis, Biopsy, and Drug Delivery Vehicles (SD2003-270)
- Lipids for Local Eye Therapy for Diseases (SD2003-113)
- Use of Guanidination to Modify Natural products as Cellular Delivery Vehicles (SD2002-135)
- Transport Molecules from Dendritic Oligo-Guanidines (SD2002-042)
- A New Family of Anti-Viral Agents and Related High-Throughput Screens (SD2000-074)
- A Macromolecular Carrier for Medical Imaging and Diagnostics (SD1998-088)
- Novel, Virus-Independent In Vivo Gene Therapy Approach (SD1998-035)
- Enhanced Transfection Efficiency in the Presence of Serum (SD1998-033)
- Enhancement of Gene Transfer Using a Viral Protein Preparation (SD1997-093)
- Method for Production of Neuroblasts (SD1992-B16)
- Regulatable Retrovirus System for Genetic Modification of Cells (SD1996-B05)
- Human Methods and Use of CNS Cell Lines (SD1998-A34)
- Metal Artifact Reduction in CT Scanning (SD2012-195)
- Optical Space-Time Coding Technique in Microfluidic Devices (SD2012-002)
- Use of PAK Inhibitors as Cancer Therapeutics and Biomarkers for Prognosis and Monitoring (SD2011-351)
- Tunable Contrast Agents for Biomarker-Specific Ultrasound Imaging (SD2011-349)
- Molecular Mechanisms of Hepatocellular Carcinogenesis, Diagnosis, and Treatment (SD2011-346)
- An Automatic MEG Method for Diagnosing and Monitoring of Neuronal and Psychiatric Disorders Including Mild and Moderate Traumatic Brain Injury (SD2011-345)
- Diagnosis and Treatment of Arthritis Using Epigenetics (SD2011-318)
- Efficient Method of Mapping Sources of Abnormal Routes of Vascular Circulation Regardless of Their Location Using MRI (SD2011-314 and SD2007-238)
- A Novel Method to Increase the Perfusion Signal to Noise Ratio (SNR) in Velocity Selective Arterial Spin Labeling for MRI (SD2011-312)
- A Restriction Spectrum Imaging Method and Device for Probing Tissue Microstructure (SD2011-311)
- Methods of Using Porous Silicon Nano/Micro-Particles for Time-Gated Fluorescence Imaging (SD2011-306)
- New Therapeutic and Diagnostic Approaches for Liver Fibrosis (SD2011-295)
- Highly Efficient Catalytic Microtube Engines (SD2011-286)
- Biomarkers and Genetic Tests for Autism and Other Developmental Disorders (SD2011-277)
- An Enhanced Powerful Method for Signal Processing in Medical Imaging (MEG, MRI, etc.) and Other Scientific and Engineering Applications (SD2011-252 and SD2011-822)
- Personalized Treatment of Schizophrenia and Related Disorders with Selective Agonists and Antagonists of VPAC2R (2011-199)
- Oligosaccharide to Prevent Necrotizing Enterocolitis (SD2011-192)
- Isolation of Target Biomolecules from Complex Samples Using Nano/Microscale Motors (SD2011-171)
- Ternary Interfaces for Direct and Sensitive Electronic Detection of Nucleic Acids in Complex Samples (SD2011-159)
- Alzheimer’s Disease Cellular Model for Diagnostic and Therapeutic Development Methods (SD2011-152)
- Wearable Tactile Stimulation Device for Brain Imaging and Rehabilitating Neural Disorders (SD-2011-143)
- Bacteriophage Platforms for Amplified Protein Detection Through Visible Plasmon Shifts in Gold Nanocrystal Solutions (SD2011-129)
- Method for Non-Invasive Serial Profiling of Patients for Diagnostic, Forensic, and Pharmacogenomic Studies (SD2011-123)
- Novel Biomarker and Therapeutic Target for Cardiomyopathy and Congestive Heart Failure (SD2011-107)
- Nanoconjugate for RNA-Triggered Drug Delivery Platform (SD2011-064)
- Small Molecule Screening Assay (SD2011-024)
- High Resolution, Diagnostic Imaging of Fat Composition and Regional Location (SD2011-012)
- A Novel and Powerful Method for Signal Processing in Medical Imaging (MEG, MRI, etc.) and Other Scientific and Engineering Applications (SD2010-340 and SD2010-834)
- A Novel Method for the Early Detection of Gastric and Pancreatic Cancer (SD2010-331)
- General Method for Identifying Antimicrobial Compounds and Determining Antibiotic Sensitivity (SD2010-312)
- Textile-Based Printable Electrodes for Electrochemical Sensing (SD2010-291)
- Fast GPU-Based Aperture Optimization for Online Adaptive Radiotherapy Treatment Planning (SD2010-288)
- A Novel High-Efficiency Algorithm for Optimizing Volumetric Modulated Arc Therapy (VMAT) Radiotherapy Treatment Planning (SD2010-287)
- Multiplexing of Situational Codes for the Parallel Operation of Enzyme Logic Gates (SD2010-276)
- A Novel Technology to Identify and Characterize Fiber Structure Using MRI (SD2010-273)
- Efficient Excitation of Magnetization for Compressed Sensing MRI (SD2010-262)
- New Early Diagnostic Test for Autism (SD2010-252)
- GPU-Based Ultra Fast and Ultra Low Dose Cone Beam Computed Tomography Reconstruction (SD2010-220)
- Motion-Based Detection of Biomolecular Interactions (SD2010-207)
- An Efficient MR Method for the Mapping and Measuring of Venous Oxygenation Using VSEAN (SD2010-181)
- Novel Arterial Spin Labeling (ASL) Method with 30 Percent Reduction in Scan Time for Measuring Blood Perfusion and Transit Delay (SD2010-177)
- Fluorescent Amyloid Binding Agents for Diagnosis of Alzheimer’s Disease (SD2010-162)
- Color-Space-Time Coding Method for Biodetection in Flow Cytometer (SD2010-145)
- Identification of Liver-Cancer Initiating Cells and a Method to Inhibit Their Tumorigenic Potential (SD2010-115)
- Chemically Amplified Response Strategies for Medical Sciences (SD2010-089)
- Smart Materials Capable of Programmed Shape Change (SD2010-007)
- A Superior Software Solution for Functional MEG (Magnetoencephalography) Brain Imaging (SD2009-826)
- A MRI Arterial Spin Labeling Software for Quantification of Regional and Complete Pulmonary Blood Flow (SD2009-824)
- Genetic Testing for Joubert Syndrome in the Jewish Population (SD2009-359)
- A New 4D Computer Tomography Sorting Method for Reducing Motion Artifacts (SD2009-313)
- Enzyme-Logic Biosensing for Rapid Diagnostics (SD2009-299)
- Novel and Efficient Multi-Phase Arterial Spin-Labeling Method for MRI and fMRI (SD2009-264)
- Biodegradable Luminescent Porous Silicon Nanoparticles for In Vivo Applications (SD2009-246)
- Improved Labeling of Nerves (SD2009-220)
- Compositions and Methods for Determining Cancer Stem Cell Self-Renewal Potential (SD2009-187 and SD2009-192)
- A Low Cost and Low Powered Integrated Cell-Sorting Module (SD2009-139)
- Protein Biomarkers for Kawasaki Disease (SD2009-047)
- Protein Biomarkers for Diagnosis and Treatment of Chronic Lymphocytic Leukemia (CLL) (SD2009-033)
- Magnetic Iron Oxide Nanoworms for In Vivo Tumor Targeting (SD2008-327)
- A Method of Developing Single Molecule DNA Nanoparticles as Diagnostic and
Therapeutic Agents (SD2008-237) - Clinical Immunoassays to Determine Concentration of Monoclonal Antibodies (SD2008-226)
- A Novel Method for Phenomic Sampling (SD2008-201 and SD2009-328)
- New Drug Treatment for Large B-Cell Lymphomas or Other Hematopoietic Malignancies (SD2008-071)
- Non-Invasive Method for Diagnosing and Monitoring Alzheimer's Disease (SD2008-059)
- Ultrasensitive, Ion Channel-Based Sensors (SD2008-006)
- A 10X Improvement in MR Imaging of Weak Oscillating Magnetic Fields -Multiple Alternating Balanced Steady States (MABSS) (SD2008-019)
- A New Approach to Medical Diagnostics and Therapeutics (SD2007-320)
- Novel Methods to Predict New Cardiovascular Events by Measuring Oxidized Phospholipids (OxPL), Lipoprotein (a) and Lipoprotein-Associated Phospholipase A2 Mass and Activity (Lp-PLA2) and Novel High-Throughput Assay to Quantitate Lp-PLA2 on Lipoprotein (a) and Apolipprotein B-100 Particles to Determine Cardiovascular Risk (SD2007-261)
- Non-Invasive Mapping of Perfusion Territories Using MRI (SD2007-238)
- Fast Correction of Inhomogeneous Magnetic Field Distortion in MRI (SD2007-217)
- Markers for Cardiac Conduction Tissue (SD2007-203)
- Annular Laser Trap for Cell Sorting and Behavior Analysis (SD2007-192)
- Microfluidic Flow Cytometry (SD2007-097)
- New Derivatives of Pyrone, Hydroxypyridinone, and Hydroxypyridinethione (SD2007-058)
- Digital Analysis of Gene Expression (SD2007-041)
- Method for High-Resolution MRI-Based Magnetoencephalography (MR-MEG) (SD2007-035)
- Compounds Targeting ß-Amyloid Ion Channels for Diagnosis and Treatment of Alzheimer’s Disease (SD2007-018, SD2007-056)
- Comprehensive Pharmacogenetic Approach to the Diagnosis and Treatment of Cancer (cancer bundle/SD2007-cancer)
- Methods for High Sensitivity Detection of Deletions from Genomic DNA (SD2006-249)
- A Novel Method to Predict the Response to Lithium Treatment (SD2006-070 and SD2008-101)
- A Novel Method to Diagnose, Predict Treatment Response, and Develop Treatments for Psychiatric Disorders Using Biomarkers (SD2006-073)
- Novel Markers for the Treatment and Diagnosis of Chronic Lumphocytic Leukemia (CLL) (SD2006-052)
- Isolated PTPMT1 Protein Which Mediates Insulin Production (SD2005-243)
- Method of Using Cell-Surface Proteins to Detect and Image Islet Beta Cells (SD2005-224)
- Methods for Treating Chronic Lymphocytic Leukemia (CLL) by Regulating Cell Survival (SD2005-221)
- Treatment and Diagnosis Of Chronic Lymphocytic Leukemia (CLL), Breast Cancer, And Other Cancers Through Use of a Monoclonal Antibody (SD2005-212)
- Multidentate Pyrone-Derived Chelators for Medicinal Imaging Contrast Agents (SD2005-191)
- Chemical Sensing by RIFTS-Reflective Interferometric Fourier-Transform Spectroscopy: A Robust, Self-Compensating Method for Label-Free Detection of Biomolecules (SD2005-179)
- Optical Detection of Suspended Micro-Objects Using Array Waveguides (SD2005-162)
- Detection and Validation of Biomarkers for Neuropsychiatric Disorders (SD2005-141)
- Novel Cancer and Inflammation Detection Using Medical Imaging (SD2005-138)
- New Activity of HSP90 Inhibitors Inducing Down Regulation of ZAP-70 and Inducing Apoptosis in Leukemia Cells (SD2005-094)
- Novel Biosensors for the Diagnoses of Cervical, Breast, and Other Cancers (SD2005-089)
- Biological Applications of "Smart Dust," or Porous Silicon Photonic Crystals (SD2005-038 and SD2005-044)
- A Novel Index of Assessing Atherosclerosis Regression and Plaque Stabilization (SD2005-037)
- Detecting Gene Expression With Ultrasound (SD2005-011)
- Method to Assess Anxiolytic Properties of Therapeutic Agents (SD2004-172)
- Portable Hand-Held Alveolar Oxygen and Carbon Dioxide Meter (SD2004-087)
- Magnetic Navigation System for Diagnosis, Biopsy, and Drug Delivery Vehicles (SD2003-270)
- Regulating Genes in the COX-2 Pathway for Colon Cancer (SD2003-261)
- ChIP-DSL: A New Technology for Genome Mapping of Functional DNA Elements and Cellular Proteins (SD2003-244)
- Cell Surface Dietary Marker in Cancer and Immune Disease (SD2003-141, SD2003-142)
- Non-Invasive, Sensitive Diagnostic for Viral Myocarditis (SD2003-099)
- Digital Molecular Sensor (SD2003-060)
- Multiparallel Three Dimensional Optical Microscopy System (SD2003-056)
- Transport Molecules from Dendritic Oligo-Guanidines (SD2002-042)
- Improved Perfusion Imaging Using MRI With Velocity-Selective Arterial Spin Labeling Without Spatial Selectivity (SD2001-175)
- Optical Switching and Sorting of Biological Samples and Microparticles in a Micro-Fluidic Device (SD2001-051)
- Diagnostic and Analytical Applications for Bovine and Human Anti-Trichomonad Monoclonal Antibodies (SD2000-131)
- Genome-Wide Gene Expression Profiling, Alternative Splicing Monitoring, and Genotyping with Direct Template Annealing Oligo-Ligation (SD2000-095)
- Gene Targets for Neuropsychiatric Disorders (SD2000-094)
- Assessing Risk for Arterial Calcification (SD1999-C79)
- A Novel Blood/Urine Test for the Detection of Acute Venous Thromboembolic Disease (1999-114)
- Diagnostics for Diseases of Abnormal Protein Glycosylation (SD1999-001)
- Diagnosis of Cancers with Metastatic Potential (SD1998-D00)
- Diagnostic Imaging of Lymph Structures (SD1998-120)
- Novel, Virus-Independent In Vivo Gene Therapy Approach (SD1998-035)
- Enhanced Transfection Efficiency in the Presence of Serum (SD1998-033)
- Hydrogen Peroxide Sensing Electrode (SD1998-014)
- Enhanced Transfection Efficiency in the Presence of Serum (SD1997-093)
- Vaccines with Enhanced Intracellular Processing (SD1997-065)
- Novel Reagents for Improved Clinical Diagnosis and Assessment of Atherosclerosis (SD1996-045)
- Assay of GTP/GDP Bound to RAS and Other G Proteins (SD1994-B09)
- Treatment of Disorders with Shortened Red Blood Cell Survival (SD1993-B35)
- Method for Selective Methionine Starvation of Malignant Cells (SD1992-C83)
- Prognostic and Diagnostic Serum Biomarker for Cancer and Inflammatory Disease (SD1992-C06 and SD1998-C98)
- Methods for the Detection of BCR-ABL and Abnormal ABL Proteins in Leukemia Patients (SD1990-C65)
- A New Portable Device to Treat Stroke Victims ‘In The Field’ (SD2012-267)
- Preventing Breakdown of Tissues in Shock and Multi-Organ Failure (SD2012-109)
- Aerated Contact Lens Made of Hard Materials (SD2012-101)
- Optical Space-Time Coding Technique in Microfluidic Devices (SD2012-002)
- Method to Rapidly Enhance Extracellular Matrix Content of Tissue Engineered Constructs (SD2011-339)
- A Restriction Spectrum Imaging Method and Device for Probing Tissue Microstructure (SD2011-311)
- Isolation of Target Biomolecules from Complex Samples Using Nano/Microscale Motors (SD2011-171)
- A Biomimetic Method for Creating Transplantable Cartilage-Bone Grafts (SD2011-165)
- Individual Mobility Sensor for Automatic Fall Evaluation (IMSAFE) (SD2011-154)
- Wearable Tactile Stimulation Device for Brain Imaging and Rehabilitating Neural Disorders (SD-2011-143)
- Wirelessly Powered and Controlled Electrical Signal Generator for Lab-on-a-Chip Devices (SD2011-113)
- Novel Oral Airway with Built-In Bite Block (SD2011-093)
- Wirelessly Powered Microfluidic Devices (SD2011-085)
- 3-D Eye-Tracking Bio-Cursor for Use in Virtual Reality, Architectural Design, and Bio-Engineering (SD2011-060)
- A Novel Dynamic Shielding Applicator for High Dose Rate Brachytherapy (SD2011-056)
- Nano-Wire Based Retinal Implants (SD2010-348)
- Dynamically Adaptive Conserver for COPD Patients on O2 Therapy (SD2010-344)
- Inorganically Surface Modified Polymers for Orthopaedic and Spinal Implants (SD2010-337)
- Wireless Non-Contact Biopotential Gradient Sensor (SD2010-311)
- Infinite Input Impedance Biopotential Amplifier (SD2010-310)
- Textile-Based Printable Electrodes for Electrochemical Sensing (SD2010-291)
- Multiplexing of Situational Codes for the Parallel Operation of Enzyme Logic Gates (SD2010-276)
- A Cartilage Compression Device for the Early Detection of Osteoarthritis (SD2010-248)
- Newborn Heart Rate Monitoring Device (SD2010-229)
- Device and Method for Selective Removal of Bone Versus Soft Tissue Using Ultrashort Laser Pulses and Spectroscopic Feedback (SD2010-154)
- Color-Space-Time Coding Method for Biodetection in Flow Cytometer (SD2010-145)
- Device for Real-Time Evaluation and Repair of Damaged Cartilage (SD2010-114)
- Chemically Amplified Response Strategies for Medical Sciences (SD2010-089)
- New Muscle Biopsy Clamp (SD2009-363)
- Enzyme-Logic Biosensing for Rapid Diagnostics (SD2009-299)
- “Lab on Chip” Device System with a Magnetic Clamp for Sealing Microfluidic Chips Against Wet Surfaces (SD2009-273)
- Method for Removing Intestinal Gases from Premature Babies (SD2009-229)
- CT-Guided Focused Ultrasound for Stroke Treatment (SD2009-153)
- A Low Cost and Low Powered Integrated Cell-Sorting Module (SD2009-139)
- New Surface for Accelerated Cartilage Cell Growth (SD2009-001)
- Clinical Immunoassays to Determine Concentration of Monoclonal Antibodies (SD2008-226)
- System for Tracking Sharps and Tools in the Operating Room (SD2008-171)
- Adjustable and Life-Like Laryngoscopy Simulator (SD2008-162)
- Calorie Pacer (SD2008-160)
- Non-Contact Biopotential Sensor (SD2008-143)
- A Duplexed Multiline Multiphoton Microscope (SD2008-074)
- Ultrasensitive, Ion Channel-Based Sensors (SD2008-006)
- Universal Toy Adaptor for Children with Disabilities (SD2007-314)
- Spinal Multi-segmental Cell and Drug Delivery System (SD2007-267)
- Non-Invasive Mapping of Perfusion Territories Using MRI (SD2007-238)
- Comfortable Nasal Lavage (SD2007-207)
- Intra-Cavity Miniature Portable Visualization System For Surgery (SD2007-197)
- Ultrashort Echo Time (UTE) Spectroscopic Imaging of Tissues with Short Transverse Relaxation Time (T2) (SD2007-131)
- Method for High-Resolution MRI-Based Magnetoencephalography (MR-MEG) (SD2007-035)
- A Method for Controlling the Release of Drugs (SD2007-033)
- NanoCon—A New Nanotechnology for Targeted Drug Delivery (SD2007-027)
- Device for Near-Field Scanning in Microfluidic Channels (SD2006-299)
- Article Comprising Large-Surface-Area Biocompatible Materials and Method of Manufacture Thereof (SD2006-261)
- PNEUFLOW™: A Device for Increasing Tissue Blood Flow (SD2006-185)
- Method for Manipulating and Heating of Discrete Droplets Using Magnetic Particles Derived from Porous Silicon (SD2006-176)
- FlexoPred: New Tool For Protein Engineering (SD2006-123)
- New Surface for Orthopedic of Dental Implants and Accelerated Cell Growth (SD2005-225)
- Multidentate Pyrone-Derived Chelators for Medicinal Imaging Contrast Agents (SD2005-191)
- Treating Disorders Associated With Inflammation (SD2005-123)
- A Novel Capillary Gun for Ballistic Delivery of Microscopic Particles into Tissue and Cultured Cells (SD2004-207)
- Real-Time Prediction and Prevention of Seizures (SD2004-091)
- Mental Improvement Through Magnetic Stimulation (SD2004-090)
- Portable Hand-Held Alveolar Oxygen and Carbon Dioxide Meter (SD2004-087)
- NoScar ThinFilm: A biocompatible polymer film for post-surgical scar reduction (SD2004-028)
- Magnetic Navigation System for Diagnosis, Biopsy, and Drug Delivery Vehicles (SD2003-270)
- Hyperecho Diffusion-Weighted Magnetic Resonance Imaging (SD2003-177)
- Improved Fluorescent Molecular Rotors for Viscosity Measurement in Small Volumes (SD2003-145)
- Multiparallel Three Dimensional Optical Microscopy System (SD2003-056)
- Laser-Based Method to Induce and Image Cortical Microstrokes In-Vivo for Preclinical Analyses (SD2003-021)
- Controlled Mineralization of a Matrix (SD2002-B28)
- Improved Perfusion Imaging Using MRI with Velocity-Selective Arterial Spin Labeling Without Spatial Selectivity (SD2001-175)
- New Method for Analyzing MRI Diffusion Data (SD2001-084)
- Optical Switching and Sorting of Biological Samples and Microparticles in a Micro-Fluidic Device (SD2001-051)
- System for Peripheral Vision Scotoma Screening (SD1999-059)
- Tissue Oxygen Distribution by Pulse Oximetry (SD1999-027)
- Direct Communication by Brain Signaling (SD1999-002)
- Hydrogen Peroxide Sensing Electrode (SD1998-014)
- Control of Skeletal Muscle Fatigue During Electrical Stimulation (SD1993-303)
Antibodies
Cell Lines
Mice
Nucleic Acids
OtherResearch reagents developed at UC San Diego are listed on the technology transfer Web site at: Research Reagents and Cell Lines.
Research Tools - Screening Assays
- A Tool for Finding Novel Agonists and Antagonists of ERα and ERβ (SD2012-156)
- Optical Space-Time Coding Technique in Microfluidic Devices (SD2012-002)
- Automated Maze for Behavioral Assessment of Working Memory in Rodents (SD2011-367)
- Automated System for High Throughput Screening in Rodents (SD2011-207)
- Isolation of Target Biomolecules from Complex Samples Using Nano/Microscale Motors (SD2011-171)
- Ternary Interfaces for Direct and Sensitive Electronic Detection of Nucleic Acids in Complex Samples (SD2011-159)
- Small Molecule Screening Assay (SD2011-024)
- Motion-Based Detection of Biomolecular Interactions (SD2010-207)
- Improved “One and Two Yeast Hybrid” Systems for Individually Arrayed Libraries (SD2010-069)
- Monitoring Atherosclerosis Regression, Plaque Stabilization, and Cardiovascular Risk Using a Novel Method to Quantify Oxidized Phospholipids (SD2009-236)
- Compositions and Methods for Activating Toll-Like Receptors (SD2009-057)
- Compositions and Methods for Preventing and Treating Anthrax Diseases (SD2009-056)
- Beta-Arrestin Biased GPCR Agonists for Inflammation and Metabolic Disease (SD2009-028)
- A Fragment Library for the Composition and Methods Used to Design and Develop Metallo-Enzyme Inhibitors (SD2009-022)
- Analysis of Endocrine Disruption Using an Aquatic Multi-Species Microarray (SD2009-012)
- Fluorescent Proteins with Increased Photostability (SD2008-123)
- A Method to Measure Neurotransmitters In Vivo (SD2007-283)
- Moldable Polycarbonate Based Biosensors (SD2007-167)
- Generation and Modulation of Cancer Stem Cells (SD2007-099)
- In Vivo Screen for Agents Affecting Erythroid Development and Disease (SD2007-090)
- The Integrin Activation Interface (SD2007-053)
- Digital Analysis of Gene Expression (SD2007-041)
- Method for Identifying Drug Targets Using Sequence Data (SD2007-022)
- Compounds Targeting ß-Amyloid Ion Channels for Diagnosis and Treatment of Alzheimer’s Disease (SD2007-018, SD2007-056)
- Zebrafish Model for Atherosclerosis (SD2007-014)
- Assay for Small Molecules and Defined Factors to Trigger Renewal of Cardiac Progenitors (SD2006-211)
- A Modulated Dielectrophoretic System for Ex-Vivo Diagnostics, Drug Monitoring, and Disease Management (SD2006-207)
- A High Throughput Assay to Identify Drug Candidates Targeting Protein Kinase A in Non-ATP Binding Sites (SD2006-160)
- Chemical Sensing by RIFTS-Reflective Interferometric Fourier-Transform Spectroscopy: A Robust, Self-Compensating Method for Label-Free Detection of Biomolecules (SD2005-179)
- Mouse Model for Macular Degeneration (SD2005-163)
- Acid-Reactive Antibodies for Therapy and Research Applications (SD2005-142)
- Biological Applications of "Smart Dust," or Porous Silicon Photonic Crystals (SD2005-038 and SD2005-044)
- Method to Assess Anxiolytic Properties of Therapeutic Agents (SD2004-172)
- Expression of Human CYP1A1 in Mice (SD2004-162)
- “Smart Dust,” or Porous Silicon Photonic Crystals (SD2004-032)
- ChIP-DSL: A New Technology for Genome Mapping of Functional DNA Elements and Cellular Proteins (SD2003-244)
- Complex Optical Encoding of Porous Silicon Photonic Crystals (SD2003-214)
- Screening Method to Discover a New Candidate Therapeutic for Type II Diabetes (SD2003-202)
- Method for Generating a Progenitor Population from Postnatal Hearts (SD2003-140)
- A Method for Screening for Therapeutics for Neuropsychiatric Disorders Using a Norway Rat Model (SD2003-091)
- A Novel Genetic Method for Generating Gain-of-Function Mutations (SD2001-107)
- Optical Switching and Sorting of Biological Samples and Microparticles in a Micro-Fluidic Device (SD2001-051)
- Genome-Wide Gene Expression Profiling, Alternative Splicing Monitoring, and Genotyping with Direct Template Annealing Oligo-Ligation (SD2000-095)
- A Method to Inhibit I-Kappa-Beta Kinase, and Screen Drugs to Target Same (SD2000-015)
- Murine Cell lines for studing innate immunity and myeloid progenitors (SD1999-053)
- Rapid Diagnostic Assay for Cytolytic T-Cell Killing of Target Cells (SD1998-062)
- Novel Screening Method for Drugs that Modulate Transcription (SD1997-102)
- Device for Detection of Organic Compounds, Ions and Other Molecular Species by Optical Interference in a Porous Silicon Layer (SD1997-064)
- Assay of GTP/GDP Bound to RAS and Other G Proteins (SD1994-B09)
- Prognostic and Diagnostic Serum Biomarker for Cancer and Inflammatory Disease (SD1992-C06 and SD1998-C98)
- Retrovirus Detection (SD1988-B08)
Research Tools - Genomics and Related DNA / RNA Methods
- A Superior Method for Designing Padlock Probes for Targeted Genomic Sequencing (SD2011-310)
- Systemic Delivery and Regulated Expression of Paracrine Genes for Cardiovascular Diseases and Other Conditions (SD2012-210)
- Isolation of Target Biomolecules from Complex Samples Using Nano/Microscale Motors (SD2011-171)
- Methods and Systems for DNA Sequencing By Denaturation (SD2011-158)
- The MEME Suite: Motif-Based Sequence Analysis Tools (SD2010-808)
- Stabilized Metal-Organic Frameworks (SD2010-245)
- Motion-Based Detection of Biomolecular Interactions (SD2010-207)
- Targeted Amplification of Mammalian Genome Sequences Using a Novel Deep Sequencing Approach: High Resolution Analysis of Mammalian Transcriptomes Using Designed Primers (SD2010-121)
- Improved “One and Two Yeast Hybrid” Systems for Individually Arrayed Libraries (SD2010-069)
- Superior Software for Designing Oligonucleotide Probe Pool: PP-Designer v2.0 (SD2009-831)
- Mostly Natural DNA Sequencing by Synthesis (SD2009-286)
- Methods and Systems for Direct Sequencing of Single DNA Molecules (SD2009-127)
- Proteins That Fluoresce in the Infrared or Generate Singlet Oxygen (SD2008-303)
- High-Level Expression of Proteins from a Stably Segregating B. Subtilis Plasmid (SD2008-278)
- A Novel Method for Phenomic Sampling (SD2008-201 and SD2009-328)
- Genome-Scale Kinetic Models (SD2008-180)
- New Molecular Technique for Neural Tracing (SD2008-166)
- A New Approach to Medical Diagnostics and Therapeutics (SD2007-320)
- T7 Transcription Enhancing Sequence (TEnBOX), Which Overexpresses Gene Products (SD2007-208)
- A Novel Technique for Fabricating Biomolecular Nano-Arrays Enabling High-DNA Amplification and Sequencing (SD2007-085)
- Digital Analysis of Gene Expression (SD2007-041)
- TimeSTAMP: Drug Controlled Molecular Tags for Visualizing Protein Turnover (SD2007-039)
- Uncovering the Genetic Basis of Phenotypic Change (SD2007-024)
- Genome-Scale Reconstruction of Human Metabolism (SD2006-294)
- Methods for High Sensitivity Detection of Deletions from Genomic DNA (SD2006-249)
- A Novel Method to Predict the Response to Lithium Treatment (SD2006-070 and SD2008-101)
- Chemical Sensing by RIFTS-Reflective Interferometric Fourier-Transform Spectroscopy: A Robust, Self-Compensating Method for Label-Free Detection of Biomolecules (SD2005-179)
- "Smart Dust,” or Porous Silicon Photonic Crystals (SD2004-032)
- ChIP-DSL: A New Technology for Genome Mapping of Functional DNA Elements and Cellular Proteins (SD2003-244)
- Complex Optical Encoding of Porous Silicon Photonic Crystals (SD2003-214)
- Determination of Protein Size (SD2003-182)
- Method for Automated Injection of Drosophila Embryos (SD2002-167)
- Novel Recyclable Silylation Reagent for Use in Generating Protecting Groups in Large-Scale Oligonucleotide Manufacture (SD2002-164)
- Novel Single Nucleotide Polymorphisms (SNPs) Associated with Hypertension (SD2001-215)
- Optical Switching and Sorting of Biological Samples and Microparticles in a Micro-Fluidic Device (SD2001-051)
- Automated Cell and Tissue Extraction and Solid Phase Capture Device (SD2001-007)
- Gene Targets for Neuropsychiatric Disorders (SD2000-094)
- Time-saving Method for Solid Phase Isolation of Proteins, Nucleic Acids and Other Macromolecules (SD1998-108)
- Device for Detection of Organic Compounds, Ions and Other Molecular Species by Optical Interference in a Porous Silicon Layer (SD1997-064)
- Recombinant Luciferase Gene, Luciferase Fusion Proteins and Methods of Use (SD1984-C05)
Research Tools - Proteomics and Related Protein Methods
- A Software for Top-Down Spectral Deconvolution and Protein Identification (SD2012-815)
- Algorithm for MSI Analysis by Semi-Supervised Segmentation (AMASS) (SD2012-067 and SD2012-807)
- A Superior Method for High-Level Production of Recombinant Protein (SD2009-147)
- Protein Biomarkers for Diagnosis and Treatment of Chronic Lymphocytic Leukemia (CLL) (SD2009-033)
- Large-Scale Quantitative Phosphoproteome Profiling (SD2008-267)
- A Novel Method for Phenomic Sampling (SD2008-201 and SD2009-328)
- Genome-Scale Kinetic Models (SD2008-180)
- New Tools for Protein Functional Site Characterization (SD2007-112)
- Method for Identifying Drug Targets Using Sequence Data (SD2007-022)
- Genome-Scale Reconstruction of Human Metabolism (SD2006-294)
- Active Microelectronic Array for Massively Parallel Peptide Synthesis and Binding Constant Analysis (SD2006-208)
- In vivo Protein Labeling (SD2005-272)
- Chemical Sensing by RIFTS-Reflective Interferometric Fourier-Transform Spectroscopy: A Robust, Self-Compensating Method for Label-Free Detection of Biomolecules (SD2005-179)
- Biological Applications of "Smart Dust," or Porous Silicon Photonic Crystals (SD2005-038 and SD2005-044)
- “Smart Dust,” or Porous Silicon Photonic Crystals (SD2004-032)
- Complex Optical Encoding of Porous Silicon Photonic Crystals (SD2003-214)
- Determination of Protein Size (SD2003-182)
- Digital Molecular Sensor (SD2003-060)
- The Use Of Deuterium Exchange-Mass Spectrometry To Enhance Large-Scale Protein Crystallographic Structure Determination (SD2002-157)
- Fluorescent Tagged Synaptic Proteins as Models for Neurodegenerative Disorders (SD2001-019)
- Automated Cell and Tissue Extraction and Solid Phase Capture Device (SD2001-007)
- The Total Synthesis of Monatin (SD2000-175)
- Method to Quantitate Oxidized LDL Epitope Content (2000-062)
- Time-saving Method for Solid Phase Isolation of Proteins, Nucleic Acids and Other Macromolecules (SD1998-108)
- Device for Detection of Organic Compounds, Ions and Other Molecular Species by Optical Interference in a Porous Silicon Layer (SD1997-064)
- Protein Recruitment System (SD1996-001)
- Recombinant Luciferase Gene, Luciferase Fusion Proteins and Methods of Use (SD1984-C05)
Research Tools - Bioinformatics
- Logical Structure of Amino Acid Stimulons in Bacteria (SD2012-348)
- Methods and Systems for DNA Sequencing By Denaturation (SD2011-158)
- Method for Assessing Physiological Response to Drug Target Inhibition (SD2010-267)
- A New Bacterial Metastructure and Methods of Use (SD2010-138)
- Mostly Natural DNA Sequencing by Synthesis (SD2009-286)
- A Powerful Computational Approach to Identify Surface of Protein-Protein Interaction (SD2009-193)
- Methods and Systems for Direct Sequencing of Single DNA Molecules (SD2009-127)
- A Systems Biology Approach for Identifying Drug Targets (SD2009-054)
- A Method to Generate Novel Bioactive Molecules (SD2008-230)
- HESA: Hepatic Encephalopathy Screening Algorithm (SD2007-804)
- New Tools for Protein Functional Site Characterization (SD2007-112)
- A Novel Technique for Fabricating Biomolecular Nano-Arrays Enabling High-DNA Amplification and Sequencing (SD2007-085)
- TimeSTAMP: Drug Controlled Molecular Tags for Visualizing Protein Turnover (SD2007-039)
- Method for Identifying Drug Targets Using Sequence Data (SD2007-022)
- Genome-Scale Reconstruction of Human Metabolism (SD2006-294)
- Novel Algorithms and Software for Mapping Complex Networks (SD2006-258)
- FlexoPred: New Tool For Protein Engineering (SD2006-123)
- Euler V2.0 (SD2004-827)
- Digital Molecular Sensor (SD2003-060)
- Protein Kinase Resource (PKR) (SD2003-801)
- CKAAPS DB: A Conserved Key Amino Acid Positions Database (SD2002-826)
- Biostar: Molecular Biology Annotation and Dissemination Tool (SD2001-815)
- MC-CE - Monte Carlo Combinatorial Extension, Algorithms & Computer Programs for Comparing and Aligning Multiple 3-D Structures of Protein Molecules (SD2001-816)
Research Tools - Other Software
- High Resolution, Diagnostic Imaging of Fat Composition and Regional Location (SD2011-012)
- Fast GPU-Based Aperture Optimization for Online Adaptive Radiotherapy Treatment Planning (SD2010-288)
- A Novel High-Efficiency Algorithm for Optimizing Volumetric Modulated Arc Therapy (VMAT) Radiotherapy Treatment Planning (SD2010-287)
- A System for Automated Pathology Slide Analysis and Image Compression (SD2010-261)
- A Systems Biology Approach for Identifying Drug Targets (SD2009-054)
- Method for Identifying Drug Targets Using Sequence Data (SD2007-022)
- Novel Algorithms and Software for Mapping Complex Networks (SD2006-258)
- Simulation-Based Probabilistic Assessment of Chromosome Segment Sharing in Arbitrary Geneologies (SD2004-164)
- Clinical Trials Management System (SD2004-082)
- GenePalette: Software For Genome Sequence Navigation And Analysis (SD2002-853)
- Splicing Graph Genome Assembler Software Modules - EULER-TC (SD2002-822)
- Splicing Graph Genome Assembler Software Modules - EULER-PCR (SD2002-821)
- Splicing Graph Genome Assembler Software Modules - EULER-EC (SD2002-820)
- Splicing Graph Genome Assembler Software Modules - EULER-Connect (SD2002-819)
- Splicing Graph Genome Assembler Software Modules - EULER-Compare (SD2002-818)
- FADE and PADRE (SD2002-817)
- Open MMS (SD2002-814)
- The MEME Suite: Motif-Based Sequence Analysis Tools (SD2002-802, 2010-808)
- A Tool for Finding Drugs for Treating Neurodegenerative Diseases in the Brain (2012-170)
- A Mathematical Model of Ventilation and Perfusion (SD2011-807)
- Brain Extracellular Matrix Compositions and Methods (SD2011-253)
- Bacteriophage Platforms for Amplified Protein Detection Through Visible Plasmon Shifts in Gold Nanocrystal Solutions (SD2011-129)
- An Implantable Cortical Linear-Array Electrode for Improving the Signal Quality of Isolated Neurons in the Cortical Tissue Layers of Primates (SD2011-084)
- Method for Modeling Metabolic Host-Pathogen Interactions (SD2011-063)
- Platform Strains for Metabolic Engineering of Bioactive Compounds (SD2011-034)
- Heads-Up Virtual Reality Device (SD2011-029)
- A System for Automated Pathology Slide Analysis and Image Compression (SD2010-261)
- GPU-Based Ultra Fast and Ultra Low Dose Cone Beam Computed Tomography Reconstruction (SD2010-220)
- Color-Space-Time Coding Method for Biodetection in Flow Cytometer (SD2010-145)
- A New 4D Computer Tomography Sorting Method for Reducing Motion Artifacts (SD2009-313)
- Plasmonic Dark Field Microscopy (SD2009-289)
- A New Palladium Catalyst System (SD2009-275)
- “Lab on Chip” Device System with a Magnetic Clamp for Sealing Microfluidic Chips Against Wet Surfaces (SD2009-273)
- High-Speed Laser Interference Structured Illumination Microscopy (SD2009-221)
- Improved Labeling of Nerves (SD2009-220)
- High-Speed Plasmonic Structured Illumination Microscopy (SD2009-202)
- A Low Cost and Low Powered Integrated Cell-Sorting Module (SD2009-139)
- Adjustable and Life-Like Laryngoscopy Simulator (SD2008-162)
- Non-Invasive Method for Diagnosing and Monitoring Alzheimer’s Disease (SD2008-059)
- Dendrimer Modified Oligonucleotides for High Yield Singly Modified Nanoparticle Probes (SD2007-037)
- Uncovering the Genetic Basis of Phenotypic Change (SD2007-024)
- A Modulated Dielectrophoretic System for Ex-Vivo Diagnostics, Drug Monitoring, and Disease Management (SD2006-207)
- Polyamine Ligands for Use as Metalloproteinase Inhibitors (SD2006-069)
- High-Throughput Functional Evaluation of Mouse Phenotype (SD2005-201)
- Multidentate Pyrone-Derived Chelators for Medicinal Imaging Contrast Agents (SD2005-191)
- Multipotent Amniotic Fetal Stem Cells: A Novel Source of Human Stem Cells (SD2005-041)
- Animal Model to Detect the Presence of Environmental Toxicants (SD2004-144)
- Clinical Use of Ultrashort TE Pulse Sequences in MRI (SD2004-056)
- Robust Image Reconstruction Software for Phased Array Coil Data in MRI (SD2003-183)
- Improved Fluorescent Molecular Rotors for Viscosity Measurement in Small Volumes (SD2003-145)
- Combinatorial Transcription Control (SD2003-087)
- Multiparallel Three Dimensional Optical Microscopy System (SD2003-056)
- A New Construct for Creating Conditional Knock-Outs in Mice (SD2003-037)
- Method for Fast Atomic Density Evaluation (SD2003-027)
- New Medical Coding/Billing Tools for Physicians and Coders (SD2002-811)
- Automated Nociception Analyzer/Flinch Monitor (SD1998-024)
- Methods for the Detection of BCR-ABL and Abnormal ABL Proteins in Leukemia Patients (SD1990-C65)
- Recombinant Luciferase Gene, Luciferase Fusion Proteins and Methods of Use (SD1984-C05)
Bioengineering - BioChips and BioMEMs
- Isolation of Target Biomolecules from Complex Samples Using Nano/Microscale Motors (SD2011-171)
- Enzyme-Logic Biosensing for Rapid Diagnostics (SD2009-299)
- Multiplexing of Situational Codes for the Parallel Operation of Enzyme Logic Gates (SD2010-276)
- Active Microelectronic Array for Massively Parallel Peptide Synthesis & Binding Constant Analysis (SD2006-208)
- Novel Bio-sensor Platform Based on Surface Enhanced Raman Scattering (SERS) Chip (SD2006-067_SERS Chip Bundle)
- Chemical Sensing by RIFTS-Reflective Interferometric Fourier-Transform Spectroscopy: A Robust, Self-Compensating Method for Label-Free Detection of Biomolecules (SD2005-179)
- Arrays for Functional Genomics/High Throughput Phenotyping (SD2001-085)
- Micropatterning Polyethylene Oxide (SD2001-001)
Bioengineering - Cell Culture and Tissue Engineering
- A Biomimetic Method for Creating Transplantable Cartilage-Bone Grafts (SD2011-165)
- Microstructured Biomaterials with a Tunable Negative Poisson’s Ratio (SD2011-095)
- “Lab on Chip” Device System with a Magnetic Clamp for Sealing Microfluidic Chips Against Wet Surfaces (SD2009-273)
- Article Comprising Subcutaneous Hepatocyte Transplants, Fabrication Process Thereof, and Therapeutic Method Using Such Transplants (SD2007-202)
- A Modulated Dielectrophoretic System for Ex-Vivo Diagnostics, Drug Monitoring, and Disease Management (SD2006-207)
- Biological Applications of "Smart Dust," or Porous Silicon Photonic Crystals (SD2005-038 and SD2005-044)
- “Smart Dust,” or Porous Silicon Photonic Crystals (SD2004-032)
- Self-Assembling, Self-Orienting Photonic Crystals of Porous Silicon (SD2003-257)
- Complex Optical Encoding of Porous Silicon Photonic Crystals (SD2003-214)
- Determination of Protein Size (SD2003-182)
- Use of Steady-State Oxygen Gradients to Modulate Cell Functions (SD2003-173)
- Method for 3D Cell Patterning Within Hydrogel Scaffolds (SD2003-035)
- Optically Encoded Nanoparticles (SD2002-075)
- Methods to Preserve Distinctive Characteristics of Engineered Articular Cartilage (SD2001-214)
- Methods of Tissue Repair, Regeneration, and Tissue Engineered Compositions (SD2001-205)
- Nanoporous Silicon Bioreactor (SD2001-054)
- Ex vivo Preparation of Kidney Tissue (SD1999-141)
- Novel Methods for Increasing Peripheral Blood Circulation (SD1997-098)
- Device for Detection of Organic Compounds, Ions and Other Molecular Species by Optical Interference in a Porous Silicon Layer (SD1997-064)
- Electric Field Assisted Biomolecule Transport, Capture, and Sensing in Carbonized, Porous Nanostructures (SD2011-322)
- DNA Zipper Based Devices (SD2011-238)
- Isolation of Target Biomolecules from Complex Samples Using Nano/Microscale Motors (SD2011-171)
- Porous Silicon Particles as Adjuvant to Modulate Immune Response and Deliver Antigens for Vaccination (SD2011-164)
- Bacteriophage Platforms for Amplified Protein Detection Through Visible Plasmon Shifts in Gold Nanocrystal Solutions (SD2011-129)
- Microstructured Biomaterials with a Tunable Negative Poisson’s Ratio (SD2011-095)
- Fuel-Free Nanowire Motors (SD2011-081)
- Nano-Wire Based Retinal Implants (SD2010-348)
- Inorganically Surface Modified Polymers for Orthopaedic and Spinal Implants (SD2010-337)
- Multiplexing of Situational Codes for the Parallel Operation of Enzyme Logic Gates (SD2010-276)
- Stabilized Metal-Organic Frameworks (SD2010-245)
- Motion-Based Detection of Biomolecular Interactions (SD2010-207)
- Polymeric Nano-Carriers with a Linear Dual Response Mechanism to Detect Disease (SD2010-189)
- Smart Materials Capable of Programmed Shape Change (SD2010-007)
- On-Demand Remote Control of Nanomotor Movement (SD2010-003)
- Nanomotor Based Fabrication and Patterning of Defined Nanostructures (SD2009-391)
- Pro-Drug Conjugates Able to Deliver Precise Ratios of Active Drugs (SD2009-349)
- Enzyme-Logic Biosensing for Rapid Diagnostics (SD2009-299)
- Biodegradable Luminescent Porous Silicon Nanoparticles for In Vivo Applications (SD2009-246)
- Chromatography for Diet and/or Nutrition/Chemical Control (SD2009-050)
- Nanoparticles for Targeted, In Vivo Delivery of Diverse Drug Chemotypes (2009-032)
- Magnetic Iron Oxide Nanoworms for In Vivo Tumor Targeting (SD2008-327)
- System for Tracking Sharps and Tools in the Operating Room (SD2008-171)
- Ultrasensitive, Ion Channel-Based Sensors (SD2008-006)
- pH-"Tunable" Nano-Particle Drug Delivery System (SD2006-140)
- Chemical Sensing by RIFTS-Reflective Interferometric Fourier-Transform Spectroscopy: A Robust, Self-Compensating Method for Label-Free Detection of Biomolecules (SD2005-179)
- Self-Assembling 2D and 3D Nanostructures for Nano-Photonic and Nano-Electronic IC's and Devices (SD2005-133)
- Biological Applications of "Smart Dust," or Porous Silicon Photonic Crystals (SD2005-038 and SD2005-044)
- “Smart Dust,” or Porous Silicon Photonic Crystals (SD2004-032)
- Self-Assembling, Self-Orienting Photonic Crystals of Porous Silicon (SD2003-257)
- Complex Optical Encoding of Porous Silicon Photonic Crystals (SD2003-214)
- Nanostructured Casting of Organic and Biopolymers in Porous Silicon Templates (SD2003-024)
- Determination of Protein Size (SD2003-182)
- Optically Encoded Nanoparticles (SD2002-075)
- Controlled Mineralization of a Matrix (SD2002-B28)
- Nanoporous Silicon Bioreactor (SD2001-054)
- Device for Detection of Organic Compounds, Ions and Other Molecular Species by Optical Interference in a Porous Silicon Layer (SD1997-064)
- Ternary Interfaces for Direct and Sensitive Electronic Detection of Nucleic Acids in Complex Samples (SD2011-159)
- Compositions and Methods for Preventing and Treating Anthrax Diseases (SD2009-056)
- Biological Applications of "Smart Dust," or Porous Silicon Photonic Crystals (SD2005-038 and SD2005-044)
- “Smart Dust,” or Porous Silicon Photonic Crystals (SD2004-032)
- Self-Assembling, Self-Orienting Photonic Crystals of Porous Silicon (SD2003-257)
- Complex Optical Encoding of Porous Silicon Photonic Crystals (SD2003-214)
- Determination of Protein Size (SD2003-182)
- Biosensor for nerve agents and pesticides (SD2002-159)
- Optically Encoded Nanoparticles (SD2002-075)
- Device for Detection of Organic Compounds, Ions and Other Molecular Species by Optical Interference in a Porous Silicon Layer (SD1997-064)
- Electric Field Assisted Biomolecule Transport, Capture, and Sensing in Carbonized, Porous Nanostructures (SD2011-322)
- Porous Silicon Particles as Adjuvant to Modulate Immune Response and Deliver Antigens for Vaccination (SD2011-164)
- Bacteriophage Platforms for Amplified Protein Detection Through Visible Plasmon Shifts in Gold Nanocrystal Solutions (SD2011-129)
- Stabilized Metal-Organic Frameworks (SD2010-245)
- Delivery of Therapeutically Relevant Macromolecules Using pH-Sensitive Peptide Transduction Linkages (SD2009-296)
- A New Palladium Catalyst System (SD2009-275)
- Biodegradable Luminescent Porous Silicon Nanoparticles for In Vivo Applications (SD2009-246)
- Transducible Delivery of Nucleic Acids Using Modified dsRNA Binding Domains (SD2009-213)
- Oxygen Independent E. Coli (SD2009-158)
- Analysis of Endocrine Disruption Using an Aquatic Multi-Species Microarray (SD2009-012)
- Magnetic Iron Oxide Nanoworms for In Vivo Tumor Targeting (SD2008-327)
- A Method of Developing Single Molecule DNA Nanoparticles as Diagnostic and
Therapeutic Agents (SD2008-237) - Genome-Scale Kinetic Models (SD2008-180)
- Moldable Polycarbonate Based Biosensors (SD2007-167)
- Uncovering the Genetic Basis of Phenotypic Change (SD2007-024)
- Genome-Scale Reconstruction of Human Metabolism (SD2006-294)
- Active Microelectronic Array for Massively Parallel Peptide Synthesis & Binding Constant Analysis (SD2006-208)
- A High Throughput Assay to Identify Drug Candidates Targeting Protein Kinase A in Non-ATP Binding Sites (SD2006-160)
- Isolated PTPMT1 Protein Which Mediates Insulin Production (SD2005-243)
- Chemical Sensing by RIFTS-Reflective Interferometric Fourier-Transform Spectroscopy: A Robust, Self-Compensating Method for Label-Free Detection of Biomolecules (SD2005-179)
- Lectin Type Fold as a Scaffold for Massive Sequence Variation (SD2005-108)
- Biological Applications of "Smart Dust," or Porous Silicon Photonic Crystals (SD2005-038 and SD2005-044)
- Transport Molecules from Dendritic Oligo-Guanidines (SD2002-042)
- Genome-Wide Gene Expression Profiling, Alternative Splicing Monitoring, and Genotyping with Direct Template Annealing Oligo-Ligation (SD2000-095)
- Disease Treatments Using Multimeric TNFSF Ligands (SD1999-003)
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