Biomedical Technologies
These technologies include (but are not limited to):
Individual technology cases are listed below for review, or you may search via keywords using the search feature at the top of the menu bar.
- Stimulus-Triggered Metalloenzyme Inhibitors (SD2010-123)
- Identification of Liver-Cancer Initiating Cells and a Method to Inhibit Their Tumorigenic Potential (SD2010-115)
- Adenoviral Vector with Tumor-Selective Expression (SD2009-232)
- Developing Mouse Xenograft Model for Uterine Fibroids Treatment (SD2009-207)
- Targeting Integrin for the Intervention of Tumor Growth and Metastasis (SD2009-201)
- Compositions and Methods for Determining Cancer Stem Cell Self-Renewal Potential (SD2009-192 and SD2009-187)
- A Hyaluronan-Based Nanoparticle Cisplatin Delivery System (SD2009-190)
- Biomarker Subnetwork for Diagnosis, Prognosis, and Treatment of Chronic Lymphocytic Leukemia (SD2009-180)
- Targeting B cells in Prostate Cancer (SD2009-172)
- A Method to Diagnose the Risk for and Prevent Breast Inflammation and Breast Cancer (SD2009-163)
- Novel Uses of Approved Drugs as Mucosal Vaccine Adjuvants (SD2009-040)
- Protein Biomarkers for Diagnosis and Treatment of Chronic Lymphocytic Leukemia (CLL) (SD2009-033)
- Nanoparticles for Targeted, In Vivo Delivery of Diverse Drug Chemotypes (2009-032)
- Methods to Treat Primary Breast Cancers and Prevent Metastatic Diseases (SD2008-318)
- Novel Amide Derivatives of Ethacrynic Acid for Cancer Therapy (SD2008-316)
- The Gαi–GIV Interface as a Novel Target for Anti-Metastatic Therapy (SD2008-290)
- G alpha i Is a Switch for Macrophage Chemotaxis and Tumor Cell Migration (SD2008-289)
- A Method of Developing Single Molecule DNA Nanoparticles as Diagnostic and
Therapeutic Agents (SD2008-237) - Potential Treatment for Breast Cancer With Peptides/Peptidomemetics/Small Molecules of a Defined Region of BRCA1 That Induce Apoptosis (SD2008-132)
- Cancer Therapy Method (SD2008-018)
- Compounds Targeting Misregulated Protein Kinases (SD2008-009)
- Selective Targeting and Depletion of Specific Lymphocyte Cell Populations In Vivo (SD2007-329)
- Augmenting Antigen-Specific T Cell Responses Following Vaccination Using IL-7 Cytokine Complexes (SD2007-327)
- Modification of IL-1 Enhances Biological Activity and Creates a Potent Vaccine Adjuvant (SD2007-324)
- Comprehensive Pharmacogenetic Approach to the Diagnosis and Treatment of Cancer (cancer bundle/SD2007-cancer)
- Cytokines Complexes for the Treatment of Preexisting Tumors (SD2007-227)
- Methods to Inhibit the Emergence or Progression of Hepatocellular Carcinoma With Estrogens or Estrogen Like Compounds (SD2007-190)
- Methods to Make the Early Detection of Hepatocellular Carcinoma; Methods to Inhibit the Emergence or Progression of Hepatocellular Carcinoma (SD2007-189)
- Methods to Inhibit the Emergence of Metastatic Prostate Cancer (SD2007-141)
- Generation and Modulation of Cancer Stem Cells (SD2007-099)
- In Vivo Screen for Agents Affecting Erythroid Development and Disease (SD2007-090)
- Novel Small Molecules, Gambogic Acid Analogues, As AntiCancer Agents (SD2007-082)
- New Derivatives of Pyrone, Hydroxypyridinone, and Hydroxypyridinethione (SD2007-058)
- The Integrin Activation Interface (SD2007-053)
- Oral Drug for Stimulation of Erythropoietin Levels in Anemic Patients (SD2006-267)
- Methods for High Sensitivity Detection of Deletions From Genomic DNA (SD2006-249)
- A Novel Method to Inhibit Lymphangiogenesis and Tumor Metastasis(SD2006-143)
- pH-"Tunable" Nano-particle Drug Delivery System (SD2006-140)
- Compositions and Methods for Therapeutic Cancer Vaccines (SD2006-095)
- Marine Natural Products (SD2006-079 and SD2003-248)
- Natural Products for Cancer Therapeutics (SD2006-079)
- Polyamine Ligands for Use as Metalloproteinase Inhibitors (SD2006-069)
- Novel Markers for the Treatment and Diagnosis of Chronic Lumphocytic Leukemia (CLL) (SD2006-052)
- Methods to Detect and Treat Prostate, Breast, and Other Hormone-Dependent Cancers (SD2005-274)
- Methods for Treating Chronic Lymphocytic Leukemia (CLL) by Regulating Cell Survival (SD2005-221)
- Treatment and Diagnosis of Chronic Lymphocytic Leukemia (CLL), Breast Cancer, and Other Cancers through Use of a Monoclonal Antibody (SD2005-212)
- Method for Generating Unlimited Numbers of Macrophage/Dendritic Cells and Neutrophils (SD2005-114)
- New Activity of HSP90 Inhibitors Inducing Down Regulation of ZAP-70 and Inducing Apoptosis in Leukemia Cells (SD2005-094)
- A Bispecific Molecule Comprised of a GRP-R Ligand and a Monoclonal Antibody to CD3 (SD2005-080)
- Tbx Genes Regulate Cell Cycle Partially Through Control of N-Myc Transcription (SD2005-223)
- Apoptosis Inhibitors (SD2005-E50)
- Treatment for Type II Diabetes and Cancer by Regulating Glucose Transporter Levels (SD2004-243)
- Osmotic Stress and Human Disease (SD2004-155)
- Superactive p53 (SD2004-160)
- Mice Lacking IKK Beta in Intestinal Epithelial Cells (SD2004-133)
- Novel Matrix Metalloproteinase Inhibitors (SD2004-102)
- New Anticancer Target (SD2004-088)
- In vivo Propagated Murine A20 Lymphoma Cells (SD2004-085)
- Novel Method to Inhibit Tumor Growth & Other Neovascular Diseases (SD2004-076)
- Oligonucleotides for the Treatment of Cancer and Autoimmune Diseases (SD2004-013)
- Regulating Genes in the COX-2 Pathway for Colon Cancer (SD2003-261)
- Marine Organism Yields a Patented Family of Antitumor/Antibiotic Compounds (SD2003-248)
- Chemical Tools for Analysis and Manipulation of Enzymes in Biosynthetic Proteomes (SD2003-226)
- New Therapy for Solid Tumors and other Neovascular Diseases (SD2002-241)
- Novel Therapeutic Approach for Cancer, Fibrosis and Auto-Immune Disorders (SD2002-149)
- Targeted Cancer Therapy (SD2002-020)
- Novel Markers and Gene Targets useful for the Diagnosis and Suppression of Metastasis (SD2002-005)
- A Novel Method to Detect and Inhibit Angiogenesis (SD2001-135)
- Target for Development of Inhibitors of Cancer (SD2001-134)
- Treatment of Cancer by Inducing Cell Apoptosis (SD2001-030)
- ISS-Receptor as a Drug Discovery Tool (SD2000-C22)
- A New Strategy for Leukemia Therapy (SD2000-159)
- Novel Antigen for Immunization in Cancer (SD2000-051)
- Disease Treatments Using Multimeric TNFSF Ligands (SD1999-003)
- Etodolac for the Prevention and Treatment of Prostate Cancer (SD1999-C38, 2003-C28)
- A Method to Induce CTL Response in Immune Deficient Patients (SD1999-A77)
- Diagnosis of Cancers with Metastatic Potential (SD1998-D00)
- Method for Early Diagnosis and Determination of Prognosis in Cancer (SD1998-B84)
- Diatom Nitrate Transporter Transgene Promoting Plant Growth on Low Nitrate Soils (SD1998-083)
- Selectin Inhibition: Novel Uses for an Already Approved Drug (SD1998-049)
- Vaccines with Enhanced Intracellular Processing (SD1997-065)
- Prosaposin: Therapeutic Compound for Prevention and Treatment of Pain (SD1995-177)
- Diagnostic Test for Cancer Susceptibility (SD1994-A91)
- Transcription Factor for the Regulation of Skin and Hair Development (SD1993-A27)
- Method for Selective Methionine Starvation of Malignant Cells (SD1992-C83)
- Prognostic and Diagnostic Serum Biomarker for Cancer and Inflammatory Disease (SD1992-C06 and SD1998-C98)
- A Novel Method for Diagnosing Retinoblastoma (RB) and Retinoblastoma Gene Involved Cancers (SD1987-C03)
Therapeutic Areas - Cardiovascular Diseases
- Stimulus-Triggered Metalloenzyme Inhibitors (SD2010-123)
- System and Method to Diagnose, Localize, and Treat Heart-Rhythm Disorders (SD2010-102)
- Cyclic AMP-Incompetent Adenylyl Cyclase (SD2009-312)
- Monitoring Atherosclerosis Regression, Plaque Stabilization, and Cardiovascular Risk Using a Novel Method to Quantify Oxidized Phospholipids (SD2009-236)
- Marine Natural Products (SD2006-079 and SD2003-248)
- Protein Biomarkers for Kawasaki Disease (SD2009-047)
- Novel Methods to Predict New Cardiovascular Events by Measuring Oxidized Phospholipids (OxPL), Lipoprotein (a) and Lipoprotein-Associated Phospholipase A2 Mass and Activity (Lp-PLA2) and Novel High-Throughput Assay to Quantitate Lp-PLA2 on Lipoprotein (a) and Apolipprotein B-100 Particles to Determine Cardiovascular Risk (SD2007-261)
- Markers for Cardiac Conduction Tissue (SD2007-203)
- A Novel Nitric-Oxide Releasing Drug (SD2007-196)
- Cardioprotective Effects of Catestatin (SD2007-118)
- Method for Discovering Agents that Limit Vascular Leak by Strengthening Cell-Cell Junctions (SD2007-070)
- New Derivatives of Pyrone, Hydroxypyridinone, and Hydroxypyridinethione (SD2007-058)
- The Integrin Activation Interface (SD2007-053)
- Atheroprotective Vaccine (SD2006-250)
- Assay for Small Molecules and Defined Factors to Trigger Renewal of Cardiac Progenitors (SD2006-211)
- New Target for Cardiovascular Disease and Diabetes (SD2005-165)
- Enhanced Expression of TRP Channels in IPAH (SD2005-073)
- A Novel Index of Assessing Atherosclerosis Regression and Plaque Stabilization (SD2005-037)
- CaMKII Heart Failure and Arrythmic Mice (SD2004-125)
- Novel Matrix Metalloproteinase Inhibitors (SD2004-102)
- A Practical Vaccine for Protection Against Atherosclerosis (SD2003-208)
- Method for Generating a Progenitor Population from Postnatal Hearts (SD2003-140)
- Use of Calcium Binding Proteins to Improve Cardiac Contractile Function. (SD2002-225)
- Novel Single Nucleotide Polymorphisms (SNPs) Associated with Hypertension (SD2001-215)
- C5 Epimerase for Use in Polysaccharide Production (SD2001-192)
- ISS-Receptor as a Drug Discovery Tool (SD2000-C22)
- Method to Quantitate Oxidized LDL Epitope Content (SD2000-062)
- Assessing Risk for Arterial Calcification (SD1999-C79)
- Cell Activation Factor (SD1998-076)
- Novel Recombinant Adenovirus Vectors for Tissue-Specific Gene Expression in Heart (SD1998-045)
- Novel Methods for Increasing Peripheral Blood Circulation (SD1997-098)
Therapeutic Areas - CNS Diseases
- A Method to Increase Neurogranin Function in Humans with Cognitive and Behavioral Deficits (SD2009-339)
- Selective Phospholipase A2 Inhibitors of Neurological Diseases (SD2009-298)
- Spinal Perfusion-Chamber for Chronic Regional Spinal-Cord Perfusion and Cell Delivery in Large Animals and in Humans (SD2009-208)
- Non-Invasive Physiological Manipulations of the Brain for Neurological Disorders (SD2009-178)
- Use of Anti-Inflammatory Strategies to Treat Psychosis, Delirium, and Cognitive Impairment (2009 CNS technology bundle; includes SD2008-114, SD2009-124, and SD2009-131)
- Marine Natural Products (SD2006-079 and SD2003-248)
- Peptides Targeted to the CNS for Clearance of Protein Aggregates in Alzheimer's Disease (SD2009-058)
- A Novel Agent to Mitigate Anesthetic-Induced Neurotoxicity in Neonates and the Elderly (SD2009-013)
- Amide Inhibitors of Human Secreted Phospholipase A2 (SD2009-002)
- Transplantation of Human Neural Cells for Treatment of Neurodegenerative Conditions (SD2008-210)
- A Novel Method to Lower Amyloid Beta Peptide Generation by Targeting RanBP9 (SD2008-175)
- Compositions and Methods for Diagnosing Alzheimer's Disease (SD2008-095)
- HESA: Hepatic Encephalopathy Screening Algorithm (SD2007-804)
- A Method to Measure Neurotransmitters In Vivo (SD2007-283)
- Structure Based Design of Anti-Parkinson's Disease Compounds Targeting Synuclein Oligomerization (SD2007-274)
- Promotion of Central Nervous System Neuronal Survival (SD2007-220a)
- Regeneration of Central Nervous System Axons After Trauma (SD2007-220b)
- Treatment of Multiple Sclerosis and Spinal Cord Injury Through Use of 2-Oxoamide Phospholipase A2 Inhibitors (SD2007-145)
- Method for High-Resolution MRI-Based Magnetoencephalography (MR-MEG) (SD2007-035)
- Compounds Targeting ß-Amyloid Ion Channels for Diagnosis and Treatment of Alzheimer’s Disease (SD2007-018, SD2007-056)
- Development of a specific inhibitor for PDE4A4: Therapeutic Implications in Pulmonary Disease and Nerve Regeneration (SD2006-245)
- Lead Compounds for Diagnosis and Therapy of Alzheimer's Disease (SD2006-105)
- A Novel Method to Diagnose, Predict Treatment Response, and Develop Treatments for Psychiatric Disorders Using Biomarkers (SD2006-073)
- Method to Predict Treatment Response in Generalized Social Phobia (SD2006-021)
- Enhancing Neural Recovery Following Stroke or Brain Injury (SD2006-019)
- Blocking Fibrin/Mac-1 Interaction as a Therapeutic Target for Multiple Sclerosis and Other Neuroinflammatory Diseases (SD2006-001)
- New Method for Promoting Nerve Regeneration (SD2005-155)
- Prion Protein Infection, Protection and Treatment (SD2005-004)
- Treatment for Mental Illness Through Manipulation of Neurotransmitter Profile (SD2004-218)
- Novel Therapeutic Approach for the Treatment of Autism Spectrum Disorders (SD2004-215)
- Gene Therapy for Usher Syndrome Type 1B (SD2004-074)
- NoScar ThinFilm: A Biocompatible Polymer Film for Post-Surgical Scar Reduction (SD2004-028)
- Novel Animal Model and Screening System for Anti-Psychotic Drugs (SD2003-089, SD2003-090, SD2003-091)
- Phosphatases that Regulate Gene Transcription (SD2003-061)
- Laser-Based Method to Induce and Image Cortical Microstrokes In-Vivo for Preclinical Analyses (SD2003-021)
- Alzheimer's Vaccine (SD2002-161)
- Novel Anti-Inflammatory Inhibitors of Phospholipase A2 (SD2002-133)
- Use of Neurotrophic Factors in Treating Memory Loss and Neurodegenerative Disease (SD2001-109)
- Erythropoietin and Erythropoietin Receptors in the Peripheral Nervous System (SD2001-090)
- Multi-Potent Central Nervous System Stem Cells (SD2001-052)
- ISS-Receptor as a Drug Discovery Tool (SD2000-C22)
- Gene Targets for Neuropsychiatric Disorders (SD2000-094)
- Human Methods and Use of CNS Cell Lines (SD1998-A34)
- Regulatable Retrovirus System for Genetic Modification of Cells (SD1996-B05)
- Prosaposin: Therapeutic Compound for Prevention and Treatment of Pain (SD1995-177)
- Method for Production of Neuroblasts (SD1992-B16)
Therapeutic Areas - Dermatological, Ophthalmological, Otological Diseases
- A New Method to Accelerate Tissue and Wound Healing Rates and Reduce Swelling and Scar Formation (2010-084)
- Peptide Mimics of BOTOX® Cosmeceutical Action (SD2009-225)
- Vaccines Against Acne and Acne-Associated Diseases (SD2009-183)
- Treating Mucosal Inflammation (SD2009-169)
- Antimicrobial, Liposomal Fatty Acids for Treatment of Acne (SD2009-148)
- Marine Natural Products (SD2006-079 and SD2003-248)
- A Method for Increasing Wound Healing and Controlling Hyperproliferative Cutaneous Diseases (SD2009-030)
- Device and Method to Store and Implant the Corneal Graft in DSAEK (SD2008-202)
- Small Molecule Kinase Inhibitors to Prevent Neoangiogenesis and Macular Degeneration (SD2008-152)
- TNF-alpha Inhibitor to Suppress Inflammation Without Suppressing the Innate Immune Response (SD2008-129)
- Prevent or Treat Skin and Wound Infections With A New Antimicrobial Peptide (SD2007-184)
- New Treatment or Diagnosis for Rosacea with Existing Approved Drugs (SD2007-047)
- pH-"Tunable" Nano-particle Drug Delivery System (SD2006-140)
- Enhance Wound Repair Using an Existing Approved Drug (SD2006-075)
- Mouse Model for Macular Degeneration (SD2005-163)
- Porous Photonic Crystals for Intraocular Drug Delivery (SD2005-088)
- Means to detect, treat and prevent sensorineural hearing loss (SD2004-004)
- Anti-viral and anti-microbial peptides (SD2003-079, SD2003-114 and SD2004-043)
- Lipids for Local Eye Therapy for Diseases (SD2003-113)
- Broad Spectrum Natural Protein Antibiotic (SD2002-119)
- Enhanced Photodynamic Therapy in Age-Related Macular Degeneration (SD2001-200)
Therapeutic Areas - Endocrine / GI Diseases
- Pancreastatin, A Novel Peptide Regulator of Glucose and Lipid Metabolism (SD2010-026)
- Marine Natural Products (SD2006-079 and SD2003-248)
- New Diagnostic Test for Infertility (SD2008-300)
- Compound Promoting Beta Cell Differentiation and Insulin Production (SD2008-297)
- Improved Means to Treat Intestinal Nematode Diseases of Animals and Prevent Drug Resistance (SD2008-247)
- A New Therapeutic Target to Prevent or Treat Insulin-Resistant States (SD2008-187)
- MitoNEET: A New Approach for Designing Diabetes Drugs (SD2008-040)
- Immunizations Preventing Insulin Resistance (SD2008-037)
- Method for Treatment and Prevention of Physiological Shock (SD2007-234)
- Method to Prevent Obesity and Diabetes by Modulating PARP-5 Activity (SD2007-115)
- Isolated PTPMT1 Protein Which Mediates Insulin Production (SD2005-243)
- Method of Using Cell-Surface Proteins to Detect and Image Islet Beta Cells (SD2005-224)
- Acid-Reactive Antibodies for Therapy and Research Applications (SD2005-142)
- Treatment for Type II Diabetes and Cancer by Regulating Glucose Transporter Levels (SD2004-243)
- Mouse Model of Crohn’s Disease and Method to Develop Specific Therapeutics (SD2004-154)
- DNA:GST-AtNOS1 Plasmid (SD2004-143)
- Treatment for Diabetic Cardiomyopathy (SD2004-071)
- Irradiated Bacterial Vaccine to Induce Broad Immune Response (SD2004-B86)
- Methods of Treating Gastrointestinal Inflammation (SD2004-B64)
- Novel, Validated Target for Type II Diabetes Drug Inhibitors (SD2003-238)
- Treatment of Lactic Acidosis Associated with Biguanide Anti-Diabetic Usage (SD2003-193)
- Phosphatases that Regulate Gene Transcription (SD2003-061)
- Irradiated Probiotic for Inflammatory Bowel Disease (SD2003-C32)
- Treatment of Liver Fibrosis by Induction of Stellate Cell Apoptosis (SD2001-024)
- Oligonucleotides for the Treatment of Inflammatory Bowel Disease (SD2000-C23)
- Method for Treatment and Prevention of Physiological Shock (SD1999-097)
- Prevention of Liver Fibrosis in Hepatitis by Inhibition of Stellate Cell Activation (SD1996-064)
- Prosaposin: Therapeutic Compound for Prevention and Treatment of Pain (SD1995-177)
Therapeutic Areas - Infectious Diseases
- New Method to Predict Immune Recovery (SD2010-039)
- Vaccines Against Acne and Acne-Associated Diseases (SD2009-183)
- Compositions and Methods for Activating Toll-Like Receptors (SD2009-057)
- Compositions and Methods for Preventing and Treating Anthrax Diseases (SD2009-056)
- Protein Biomarkers for Kawasaki Disease (SD2009-047)
- Novel Uses of Approved Drugs as Mucosal Vaccine Adjuvants (SD2009-040)
- G Alpha i Is a Switch for Macrophage Chemotaxis and Tumor Cell Migration (SD2008-289)
- Improved Means to Treat Intestinal Nematode Diseases of Animals and Prevent Drug Resistance (SD2008-247)
- Method for Identifying A Bacterial Toxin and Strategy for Vaccine Development (SD2008-211)
- Immunostimulatory Sequences and Vectors for Inflammatory and Infectious Diseases (technology bundle)
- New Antiviral Compounds Active Against Avian Influenza N1 (SD2008-170)
- RNA ‘Friendly’ Ligands with Anti-Viral Activity for the Treatment of Hepatitis C (SD2008-145)
- Mitigating the Lethal Coagulopathy of Sepsis (SD2008-113)
- TGF-Beta Attenuation: A New Strategy for Treating Chronic Viral Infections (SD2008-030)
- Augmenting Antigen-Specific T Cell Responses Following Vaccination Using IL-7 Cytokine Complexes (SD2007-327)
- Modification of IL-1 Enhances Biological Activity and Creates a Potent Vaccine Adjuvant (SD2007-324)
- New Treatment for Anthrax Infection (SD2007-321)
- Prevent or Treat Skin and Wound Infections With A New Antimicrobial Peptide (SD2007-184)
- In Vivo Screen for Agents Affecting Erythroid Development and Disease (SD2007-090)
- Uncovering the Genetic Basis of Phenotypic Change (SD2007-024)
- Oral Drug for Stimulation of Erythropoietin Levels in Anemic Patients (SD2006-267)
- Complementary Screens for the Development of Tuberculosis Drugs and Vaccines (SD2006-197_Composite)
- Compounds and Screens for Therapeutics against Tuberculosis and other Mycobacterial Infections (SD2006-197)
- New Vaccine for Persistent Viruses (SD2006-121)
- Marine Natural Products (SD2006-079 and SD2003-248)
- Enhance Wound Repair Using an Existing Approved Drug (SD2006-075)
- Polyamine Ligands for Use as Metalloproteinase Inhibitors (SD2006-069)
- Treatment of Intestinal Animal Parasitic Diseases in Veterinary and Human Medicine (SD2006-049)
- Novel Alkoxyalkyl Phosphate Derivatives of Nucleoside Phosphonates with Antiviral Activity. (SD2005-175)
- Acid-Reactive Antibodies for Therapy and Research Applications (SD2005-142)
- Derivatives of Novel Nucleoside Phosphonates with Anti-viral Activity (SD2005-105)
- A New Nucleoside Phosphonate Analog with Antiviral Activity (SD2004-257)
- Monoclonal Antibodies Immunoreactive with Lipolysaccharide Binding Protein (LBP) and Methods of Their Use (SD2004-221)
- Interference with the Virus-Induced CD4 Down-Modulation as an Anti-HIV Approach (SD2004-111)
- New Derivatives of Phosphonate Compounds with Enhanced Anti-viral Activity. (SD2004-100)
- Vaccines and Diagnostics Using the Native Capsule of Group B Streptococcus (SD2004-027)
- Irradiated Bacterial Vaccine to Induce Broad Immune Response (SD2004-B86)
- Marine Organism Yields a Patented Family of Antitumor/Antibiotic Compounds (SD2003-248)
- Targets for the Development of Anti-Actinomycete Drugs and Vaccines (SD2003-073)
- Use of MshC for Development of Tuberculosis Drugs and Vaccines (SD2002-094)
- Novel Compounds for the Development of TB Therapeutics (SD2001-169)
- ISS-Receptor as a Drug Discovery Tool (SD2000-C22)
- ISS is a Chemotherapeutic Agent for Mycobacterial Infections (SD2000-B58)
- A Method to Induce CTL Response in Immune Deficient Patients (SD1999-A77)
Therapeutic Areas - Inflammation & Immune Diseases
- Stimulus-Triggered Metalloenzyme Inhibitors (SD2010-123)
- New Method to Predict Immune Recovery (SD2010-039)
- In Vivo Imaging of Inflammation and Reactive Oxygen Species: Compounds and Methods (SD2009-324)
- Selective Phospholipase A2 Inhibitors of Neurological Diseases (SD2009-298)
- Treating Mucosal Inflammation (SD2009-169)
- Novel Uses of Approved Drugs as Mucosal Vaccine Adjuvants (SD2009-040)
- Marine Natural Products (SD2006-079 and SD2003-248)
- Nanoparticles for Targeted, In Vivo Delivery of Diverse Drug Chemotypes (SD2009-032)
- Synovial Joint Bioreactor (SD2009-023)
- G Alpha i Is a Switch for Macrophage Chemotaxis and Tumor Cell Migration (SD2008-289)
- Targeting Upstream Kinase MKK3 for Pain (SD2008-061)
- Immunostimulatory Sequences and Vectors for Inflammatory and Infectious Diseases (technology bundle)
- Selective Targeting and Depletion of Specific Lymphocyte Cell Populations In Vivo (SD2007-329)
- Augmenting Antigen-Specific T Cell Responses Following Vaccination Using IL-7 Cytokine Complexes (SD2007-327)
- Modification of IL-1 Enhances Biological Activity and Creates a Potent Vaccine Adjuvant (SD2007-324)
- New Use for Existing Drug to Treat Rheumatoid Arthritis, Lupus, or Other Autoimmune Diseases (SD2007-269)
- New Method To Treat Physiological Shock and Diseases of Inflammation (SD2007-128)
- New Method To Treat Septic Shock (SD2007-127)
- New Method To Reduce Complications and Hospital Stay After Radiation/Trauma/Surgery (SD2007-126)
- The Integrin Activation Interface (SD2007-053)
- Small Molecule Inhibitors of the Alpha4-Paxillin Interaction (SD2007-009)
- Combination Therapy of Immunomodulatory Peptides and a Chloroquine Derivative to Treat Rheumatoid Arthritis and Other Autoimmune Disorders (SD2006-256)
- pH-"Tunable" Nano-particle Drug Delivery System (SD2006-140)
- Prevention and Treatment of Cytomegalovirus Infection Through Immunization with Novel CMV-Derived Peptides (SD2006-074)
- Blocking Fibrin/Mac-1 Interaction as a Therapeutic Target for Multiple Sclerosis and Other Neuroinflammatory Diseases (SD2006-001)
- Gene Therapy for Osteoarthritis (SD2005-182)
- A New Approach to Treating Atherosclerosis (SD2005-161)
- Method for Generating Unlimited Numbers of Macrophage/Dendritic Cells and Neutrophils (SD2005-114)
- Lectin Type Fold as a Scaffold for Massive Sequence Variation (SD2005-108)
- Osmotic Stress and Human Disease (SD2004-155)
- Mouse Model of Crohn’s Disease and Method to Develop Specific Therapeutics (SD2004-154)
- Lysm-Cre/IKK Beta Loxlox Mice (SD2004-141)
- Villin-Cre/IKK Beta Loxlox Mice (SD2004-140)
- Mice Lacking IKK Beta in Intestinal Epithelial Cells (SD2004-133)
- Mice Lacking IKKß in Macrophages (SD2004-132)
- Mice with a Conditional IKK Beta Loss of Function (SD2004-131)
- Mice Lacking IKK Beta in Liver Cells - Models for Acute Hepatic Failure, Hepatocellular Carcinoma and Increased Sensitivity to Insulin (SD2004-130)
- Enhancement of Th2-dependent Anti-inflammatory Response (SD2004-129)
- IKK Beta Liver Knockout Cre Mice (SD2004-120)
- Novel Matrix Metalloproteinase Inhibitors (SD2004-102)
- Crossbred Mice: CK19 CRE X IKK Beta (Lox P) (SD2004-077)
- Novel Anti-Inflammatory Treatment by Blocking Signal Transduction Kinases in the Central Nervous System (SD2004-034)
- Irradiated Bacterial Vaccine to Induce Broad Immune Response (SD2004-B86)
- Methods of Treating Gastrointestinal Inflammation (SD2004-B64)
- Irradiated Probiotic for Inflammatory Bowel Disease (SD2003-C32)
- Prevention of Pathogen-induced Macrophage Apoptosis (SD2003-269)
- IKK Alpha (AA) Mice (SD2003-211)
- A Practical Vaccine for Protection Against Atherosclerosis (SD2003-208)
- Reporters for the "Alternative" NF-kB Pathway (SD2003-196)
- Floxed IKKB Mice (SD2003-195)
- MEKK1 -/- Mice (SD2003-189)
- ST3Gal-VI Sialytransferase Inhibition for the Treatment and Prevention of Inflammation (SD2002-204)
- Ihibition of a JNK Signaling Complex as a Novel Treatment for Joint Destruction and Inflammation in Arthritis (SD2002-182)
- Dominant-Negative Kinase Adenoviral Construct for Arthritis (SD2002-169)
- P53 Knockout/DBA1 Mice as an Improved Model for Rheumatoid Arthritis (SD2002-132)
- Phase II Biologic to Treat Rheumatoid Arthritis and Other Autoimmune Diseases (SD2002-051, SD2001-901, SD2000-133, SD1999-268)
- Treatment of Inflammatory Diseases (SD2001-213)
- A Method for Inhibiting B Cell Maturation and Antibody Production (SD2001-176)
- Novel Expression Vectors Containing Chimeric Ligand Genes Useful for Immunomodulation (SD2001-101, SD2001-102, SD2001-103, SD2001-104, SD2001-108)
- New Ligand Involved in the Transmigration of Leukocytes Across the Endothelium and Uses Therefor (SD2001-018)
- Mutations in IKKg Gene (SD2000-165)
- Oligonucleotides for the Treatment of Inflammatory Bowel Disease (SD2000-C23)
- ISS-Receptor as a Drug Discovery Tool (SD2000-C22)
- ISS is a Chemotherapeutic Agent for Mycobacterial Infections (SD2000-B58)
- A Method to Inhibit I-Kappa-Beta Kinase, and Screen Drugs to Target Same (SD2000-015)
- A Method to Induce CTL Response in Immune Deficient Patients (SD1999-A77)
- Gamma-Subunit of Cytokine Responsive IkBa Kinase (IKK) Complex (SD1998-107)
- Selectin Inhibition: Novel Uses for an Already Approved Drug (SD1998-049)
- Prosaposin: Therapeutic Compound for Prevention and Treatment of Pain (SD1995-177)
- Treatment of Disorders with Shortened Red-Blood Cell Survival (SD1993-B35)
- Prognostic and Diagnostic Serum Biomarker for Cancer and Inflammatory Disease (SD1992-C06 and SD1998-C98)
- Retrovirus Detection (SD1988-B08)
- Therapy for Rheumatoid Arthritis (SD1996-051)
Therapeutic Areas - Respiratory Diseases
- A MRI Arterial Spin Labeling Software for Quantification of Regional and Complete Pulmonary Blood Flow (SD2009-824)
- Novel Uses of Approved Drugs as Mucosal Vaccine Adjuvants (SD2009-040)
- Marine Natural Products (SD2006-079 and SD2003-248)
- New Drug Derivatives for Promoting Oral Delivery to the Lung (SD2004-258)
- A Novel Strategy to Treat Asthma (SD2003-217)
Therapeutic Areas - Urological Diseases
- Marine Natural Products (SD2006-079 and SD2003-248)
- Cellular Strategies for Combating Ischemic and Other Injury to Epithelial Organs (SD2001-041)
- Pancreastatin, A Novel Peptide Regulator of Glucose and Lipid Metabolism (SD2010-026)
- A New Method to Reduce Internal Organ Attachment (Adhesions) (SD2009-306)
- Selective Phospholipase A2 Inhibitors of Neurological Diseases (SD2009-298)
- Developing Mouse Xenograft Model for Uterine Fibroids Treatment (SD2009-207)
- Treatment Method for Human Muscle Contractures (SD2009-128)
- Marine Natural Products (SD2006-079 and SD2003-248)
- Chromatography for Diet and/or Nutrition/Chemical Control (SD2009-050)
- A New Method for Treatment of Insomnia (SD2008-261)
- Genome-Scale Kinetic Models (SD2008-180)
- New Antiviral Compounds Active Against Avian Influenza N1 (SD2008-170)
- Uncovering the Genetic Basis of Phenotypic Change (SD2007-024)
- Genome-Scale Reconstruction of Human Metabolism (SD2006-294)
- Biosynthesis of Salinosporamide A and Analogs (SD2006-203)
- A New Approach to Treating Atherosclerosis. (SD2005-161)
- Multipotent Amniotic Fetal Stem Cells: A Novel Source of Human Stem Cells (SD2005-041)
- Therapy for septic shock (SD2004-263)
- Monoclonal Antibodies Immunoreactive with Lipolysaccharide Binding Protein (LBP) and Methods of Their Use (SD2004-221)
- Vaccines for Streptococcal Infection in Fish (SD2004-200)
- Vaccination and Diagnosis for Histophilus somni (formerly Haemophilus somnus) (SD2004-165)
- Mice Lacking IKK Beta in Intestinal Epithelial Cells (SD2004-133)
- Clinical Trials Management System (SD2004-082)
- Gene Therapy for Usher Syndrome Type 1B (SD2004-074)
- Treatment for Smoke Inhalation and Cyanide Poisoning (SD2003-034b)
- New Treatment for Sepsis (SD2003-034)
- Transport Molecules from Dendritic Oligo-Guanidines (SD2003-144, SD2002-042)
- Controlled Mineralization of a Matrix (SD2002-B28)
- Multi-Potent Central Nervous System (CNS) Stem Cells (SD2001-052)
- Cellular Strategies for Combating Ischemic and Other Injury to Epithelial Organs (SD2001-041)
- A New Anti-Coagulant (SD2000-035)
- Disease Treatments Using Multimeric TNFSF Ligands (SD1999-003)
- New Approach to Tissue Repair (SD1997-108)
- Prosaposin: Therapeutic compound for p revention and treatment of pain (SD1995-177)
- Transcription Factor for the Regulation of Skin and Hair Development (SD1993-A27)
- Treatment of Disorders with Shortened Red Blood Cell Survival (SD1993-B35)
- Scalable Generation of Erythrocytes from Embryonic Stem Cells Can Increase the Transfusion Capacity of the Blood Supply (SD2010-045)
- Defined and Xeno-Free Serum Replacement for Maintenance of Human Embryonic Stem Cells or hESCs (SD2010-036)
- An Improved Method for Whole Genome Amplification on Trace Amount (SD2009-301)
- Epigenetic Generation of Induced Pluripotent Stem (iPS) Cells (SD2009-214)
- Spinal Perfusion-Chamber for Chronic Regional Spinal-Cord Perfusion and Cell Delivery in Large Animals and in Humans (SD2009-208)
- Compositions and Methods for Determining Cancer Stem Cell Self-Renewal Potential (SD2009-192 and SD2009-187)
- Defined Substrate for the Long-Term Maintenance of Human Embryonic Stem Cells (SD2009-181)
- Programming Stem Cell Fate Using Designed Regulatory Proteins Without Genetic Modification (SD2008-311)
- Transplantation of Human Neural Cells for Treatment of Neurodegenerative Conditions (SD2008-210)
- Simple Method for Deriving Germ Cells, Male Gametes and Supporting Sertoli-Like Cells from Human Embryonic Stem Cells (SD2007-179)
- Generation and Modulation of Cancer Stem Cells (SD2007-099)
- In Vivo Screen for Agents Affecting Erythroid Development and Disease (SD2007-090)
- Tbx Genes Regulate Cell Cycle Partially Through Control of N-Myc Transcription (SD2005-223)
- Multipotent Amniotic Fetal Stem Cells: A Novel Source of Human Stem Cells (SD2005-041)
- Multi-Potent Central Nervous System (CNS) Stem Cells (SD2001-052)
New Chemical Entities, Drug Leads
- In Vivo Imaging of Inflammation and Reactive Oxygen Species: Compounds and Methods (SD2009-324)
- Selective Phospholipase A2 Inhibitors of Neurological Diseases (SD2009-298)
- Analogs of the Cytotoxic Natural Product Mycolactone (SD2009-121)
- A Novel Agent to Mitigate Anesthetic-Induced Neurotoxicity in Neonates and the Elderly (SD2009-013)
- Amide Inhibitors of Human Secreted Phospholipase A2 (SD2009-002)
- Novel Amide Derivatives of Ethacrynic Acid for Cancer Therapy (SD2008-316)
- A New Antimitotic, Anticancer, and Antimicrobial Compound (SD2008-188)
- TNF-Alpha Inhibitor to Suppress Inflammation Without Suppessing the Innate Immune Response (SD2008-129)
- Compounds Targeting Misregulated Protein Kinases (SD2008-009)
- Ultrasensitive, Ion Channel-Based Sensors (SD2008-006)
- Reagents for Ultrasensitive, Ion Channel-Based Detection and Quantization (SD2008-006_Reagents)
- Comprehensive Pharmacogenetic Approach to the Diagnosis and Treatment of Cancer (cancer bundle/SD2007-cancer)
- Compounds Targeting ß-Amyloid Ion Channels for Diagnosis and Treatment of Alzheimer’s Disease (SD2007-018, SD2007-056)
- Biosynthesis of Salinosporamide A and Analogs (SD2006-203)
- Lead Compounds for Diagnosis and Therapy of Alzheimer's Disease (SD2006-105)
- Natural Products for Cancer Therapeutics (SD2006-079)
- Marine Natural Products (SD2006-079 and SD2003-248)
- Novel Alkoxyalkyl Phosphate Derivatives of Nucleoside Phosphonates with Antiviral Activity. (SD2005-175)
- Apoptosis Inhibitors (SD2005-E50)
- Oligonucleotides for the Treatment of Cancer and Autoimmune Diseases (SD2004-013)
- Marine Organism Yields a Patented Family of Antitumor/Antibiotic Compounds (SD2003-248)
- Isolates from Marine Invertabrates Compound Library for Drug Screening (SD2003-039)
- Etodolac for the Prevention and Treatment of Prostate Cancer (SD1999-C38, 2003-C28)
- Novel Anti-inflammatory Inhibitors of Phospholipase A2 (SD2002-133)
- Induction of RNAi Responses by PTD-Mediated Cellular Delivery of Short Interfering RiboNucleic Basics (siRNBs) Containing Biologically Labile PhosphoTriester Basic Protecting Groups (SD2009-323)
- Delivery of Therapeutically Relevant Macromolecules Using pH-Sensitive Peptide Transduction Linkages (SD2009-296)
- Transducible Delivery of Nucleic Acids Using Modified dsRNA Binding Domains (SD2009-213)
- Alternative Method for Administration of Enzyme Inhibitors (SD2009-052)
- Nanoparticles for Targeted, In Vivo Delivery of Diverse Drug Chemotypes (SD2009-032)
- Novel, On-Off Switchable, Drug Delivery Vehicles, FabricationTechniques and Applications Thereof (SD2008-144)
- Scalable, Inexpensive Method to Make Hollow Nanoparticles for Life Science Applications (SD2008-016)
- Spinal Multi-segmental Cell and Drug Delivery System (SD2007-267)
- Method for Manipulating and Heating of Discrete Droplets Using Magnetic Particles Derived from Porous Silicon (SD2006-176)
- pH-"Tunable" Nano-particle Drug Delivery System (SD2006-140)
- In Vitro Method to Improve Transfection Efficiency with In Vivo Applicability (SD2005-251)
- Optimizing Expression of Recombinant Protein in Mammalian Cells (SD2005-186)
- New Method for Promoting Nerve Regeneration (SD2005-155)
- Porous Photonic Crystals for Intraocular Drug Delivery (SD2005-088)
- Biological Applications of "Smart Dust," or Porous Silicon Photonic Crystals (SD2005-038)
- New Drug Derivatives for Promoting Oral Delivery to the Lung (SD2004-258)
- Transport Molecules from Dendritic Oligo-Guanidines (SD2003-144, SD2002-042)
- Lipids for Local Eye Therapy for Diseases (SD2003-113)
- Use of Guaninidination to Modify Natural products as Cellular Delivery Vehicles (SD2002-135)
- A New Family of Anti-Viral Agents and Related High-Throughput Screens (SD2000-074)
- A Macromolecular Carrier for Medical Imaging and Diagnostics (SD1998-088)
- Novel, Virus-Independent In Vivo Gene Therapy Approach (SD1998-035)
- Enhanced Transfection Efficiency in the Presence of Serum (SD1998-033)
- Enhancement of Gene Transfer Using a Viral Protein Preparation (SD1997-093)
- Method for Production of Neuroblasts (SD1992-B16)
- Regulatable Retrovirus System for Genetic Modification of Cells (SD1996-B05)
- Human Methods and Use of CNS Cell Lines (SD1998-A34)
- Identification of Liver-Cancer Initiating Cells and a Method to Inhibit Their Tumorigenic Potential (SD2010-115)
- System and Method to Diagnose, Localize, and Treat Heart-Rhythm Disorders (SD2010-102)
- Chemically Amplified Response Strategies for Medical Sciences (SD2010-089)
- A Superior Software Solution for Functional MEG (Magnetoencephalography) Brain Imaging (SD2009-826)
- A MRI Arterial Spin Labeling Software for Quantification of Regional and Complete Pulmonary Blood Flow (SD2009-824)
- Genetic Testing for Joubert Syndrome in the Jewish Population (SD2009-359)
- Responsive Microbubbles for Ultrasound Contrast Enhancement (SD2009-326)
- An Improved Method for Whole Genome Amplification on Trace Amount (SD2009-301)
- A Non-Invasive Method to Detect Onset of Autodigestion (SD2009-263)
- Improved Labeling of Nerves (SD2009-220)
- Compositions and Methods for Determining Cancer Stem Cell Self-Renewal Potential (SD2009-192 and SD2009-187)
- Biomarker Subnetwork for Diagnosis, Prognosis, and Treatment of Chronic Lymphocytic Leukemia (SD2009-180)
- A Low Cost and Low Powered Integrated Cell-Sorting Module (SD2009-139)
- Protein Biomarkers for Kawasaki Disease (SD2009-047)
- Protein Biomarkers for Diagnosis and Treatment of Chronic Lymphocytic Leukemia (CLL) (SD2009-033)
- Methods to Treat Primary Breast Cancers and Prevent Metastatic Diseases (SD2008-318)
- The Gαi–GIV Interface as a Novel Target for Anti-Metastatic Therapy (SD2008-290)
- A Method of Developing Single Molecule DNA Nanoparticles as Diagnostic and
Therapeutic Agents (SD2008-237) - Clinical Immunoassays to Determine Concentration of Monoclonal Antibodies (SD2008-226)
- A New Therapeutic Target to Prevent or Treat Insulin-resistant States (SD2008-187)
- Non-Invasive Method for Diagnosing and Monitoring Alzheimer's Disease (SD2008-059)
- Ultrasensitive, Ion Channel-Based Sensors (SD2008-006)
- A 10X Improvement in MR Imaging of Weak Oscillating Magnetic Fields -Multiple Alternating Balanced Steady States (MABSS) (SD2008-019)
- A New Approach to Medical Diagnostics and Therapeutics (SD2007-320)
- Novel Methods to Predict New Cardiovascular Events by Measuring Oxidized Phospholipids (OxPL), Lipoprotein (a) and Lipoprotein-Associated Phospholipase A2 Mass and Activity (Lp-PLA2) and Novel High-Throughput Assay to Quantitate Lp-PLA2 on Lipoprotein (a) and Apolipprotein B-100 Particles to Determine Cardiovascular Risk (SD2007-261)
- Microarray for High Throughput Detection of Enzymatic Activity (SD2007-252)
- Non-Invasive Mapping of Perfusion Territories Using MRI (SD2007-238)
- Fast Correction of Inhomogeneous Magnetic Field Distortion in MRI (SD2007-217)
- Markers for Cardiac Conduction Tissue (SD2007-203)
- Annular Laser Trap for Cell Sorting and Behavior Analysis (SD2007-192)
- Microfluidic Flow Cytometry (SD2007-097)
- New Derivatives of Pyrone, Hydroxypyridinone, and Hydroxypyridinethione (SD2007-058)
- Digital Analysis of Gene Expression (SD2007-041)
- Method for High-Resolution MRI-Based Magnetoencephalography (MR-MEG) (SD2007-035)
- Compounds Targeting ß-Amyloid Ion Channels for Diagnosis and Treatment of Alzheimer’s Disease (SD2007-018, SD2007-056)
- Comprehensive Pharmacogenetic Approach to the Diagnosis and Treatment of Cancer (cancer bundle/SD2007-cancer)
- Methods for High Sensitivity Detection of Deletions from Genomic DNA (SD2006-249)
- A Novel Method to Predict the Response to Lithium Treatment (SD2006-070 and SD2008-101)
- A Novel Method to Diagnose, Predict Treatment Response, and Develop Treatments for Psychiatric Disorders Using Biomarkers (SD2006-073)
- Novel Markers for the Treatment and Diagnosis of Chronic Lumphocytic Leukemia (CLL) (SD2006-052)
- Isolated PTPMT1 Protein Which Mediates Insulin Production (SD2005-243)
- Method of Using Cell-Surface Proteins to Detect and Image Islet Beta Cells (SD2005-224)
- Methods for Treating Chronic Lymphocytic Leukemia (CLL) by Regulating Cell Survival (SD2005-221)
- Treatment and Diagnosis Of Chronic Lymphocytic Leukemia (CLL), Breast Cancer, And Other Cancers Through Use of a Monoclonal Antibody (SD2005-212)
- Chemical Sensing by RIFTS-Reflective Interferometric Fourier-Transform Spectroscopy: A Robust, Self-Compensating Method for Label-Free Detection of Biomolecules (SD2005-179)
- Optical Detection of Suspended Micro-Objects Using Array Waveguides (SD2005-162)
- Detection and Validation of Biomarkers for Neuropsychiatric Disorders (SD2005-141)
- Novel Cancer and Inflammation Detection Using Medical Imaging (SD2005-138)
- Fluorscent Nucleoside Analogs That Mimic Naturally Occurring Nucleosides (SD2005-116)
- New Activity of HSP90 Inhibitors Inducing Down Regulation of ZAP-70 and Inducing Apoptosis in Leukemia Cells (SD2005-094)
- Novel Biosensors for the diagnoses of Cervical, Breast, and other cancers (SD2005-089)
- Biological Applications of "Smart Dust," or Porous Silicon Photonic Crystals (SD2005-038)
- A Novel Index of Assessing Atherosclerosis Regression and Plaque Stabilization (SD2005-037)
- Detecting Gene Expression With Ultrasound (SD2005-011)
- A Method of Ultrasound Signal Augmentation (SD2005-010)
- A Method to Detect and Treat Localized Abnormalities (SD2004-251)
- Method to Assess Anxiolytic Properties of Therapeutic Agents (SD2004-172)
- Vaccination and Diagnosis for Histophilus somni (formerly Haemophilus somnus) (SD2004-165)
- Portable Hand-Held Alveolar Oxygen and Carbon Dioxide Meter (SD2004-087)
- Vaccines and Diagnostics Using the Native Capsule of Group B Streptococcus (SD2004-027)
- Diagnostic Markers for Kawasaki Disease (SD2004-014)
- Means to detect, treat and prevent sensorineural hearing loss (SD2004-004)
- Regulating genes in the COX-2 pathway for colon cancer (SD2003-261)
- ChIP-DSL: A New Technology for Genome Mapping of Functional DNA Elements and Cellular Proteins (SD2003-244)
- Cell Surface Dietary Marker in Cancer and Immune Disease (SD2003-141, SD2003-142)
- Transport Molecules from Dendritic Oligo-Guanidines (SD2003-144, SD2002-042)
- Diagnosis of HNPCC (SD2003-064)
- Digital Molecular Sensor (SD2003-060)
- Multiparallel Three Dimensional Optical Microscopy System (SD2003-056)
- Novel Markers and Gene Targets useful for the Diagnosis and Suppression of Metastasis (SD2002-005)
- Improved Perfusion Imaging Using MRI with Velocity-Selective Arterial Spin Labeling Without Spatial Selectivity (SD2001-175)
- Diagnostic and Analytical Applications for Bovine and Human Anti-trichomonad Monoclonal Antibodies (SD2000-131)
- Gene Targets for Neuropsychiatric Disorders (SD2000-094)
- Assessing Risk for Arterial Calcification (SD1999-C79)
- A Novel Blood/Urine Test for the Detection of Acute Venous Thromboembolic Disease (1999-114)
- Diagnostics for Diseases of Abnormal Protein Glycosylation (SD1999-001)
- Diagnosis of Cancers with Metastatic Potential (SD1998-D00)
- Method for Early Diagnosis and Determination of Prognosis in Cancer (SD1998-B84)
- Diagnostic Imaging of Lymph Structures (SD1998-120)
- Novel, Virus-Independent In Vivo Gene Therapy Approach (SD1998-035)
- Enhanced Transfection Efficiency in the Presence of Serum (SD1998-033)
- Hydrogen Peroxide Sensing Electrode (SD1998-014)
- Enhanced Transfection Efficiency in the Presence of Serum (SD1997-093)
- Vaccines with Enhanced Intracellular Processing (SD1997-065)
- Diagnostic Antibodies for Tuberculosis Discriminate Active Bacterial Infection Versus Residual DNA (SD1996-092)
- Novel Reagents for Improved Clinical Diagnosis and Assessment of Atherosclerosis (SD1996-045)
- Assay of GTP/GDP Bound to RAS and Other G Proteins (SD1994-B09)
- Treatment of Disorders with Shortened Red Blood Cell Survival (SD1993-B35)
- Method for Selective Methionine Starvation of Malignant Cells (SD1992-C83)
- Prognostic and Diagnostic Serum Biomarker for Cancer and Inflammatory Disease (SD1992-C06 and SD1998-C98)
- Methods for the Detection of BCR-ABL and Abnormal ABL Proteins in Leukemia Patients (SD1990-C65)
- System and Method to Diagnose, Localize, and Treat Heart-Rhythm Disorders (SD2010-102)
- Chemically Amplified Response Strategies for Medical Sciences (SD2010-089)
- New Muscle Biopsy Clamp (SD2009-363)
- Full Body Automated Detection of Skin Lesions (SD2009-262)
- Spinal Perfusion-Chamber for Chronic Regional Spinal-Cord Perfusion and Cell Delivery in Large Animals and in Humans (SD2009-208)
- A Novel Device for Reliably Assessing Urethral Function (SD2009-160)
- Enhancement of Acousto-Optical Imaging Using Microbubbles (SD2009-038)
- Synovial Joint Bioreactor (SD2009-023)
- Clinical Immunoassays to Determine Concentration of Monoclonal Antibodies (SD2008-226)
- Pulse Oximetry Probe (SD2008-204)
- Tracking System for Sharps and Operating Room Paraphernalia (SD2008-171)
- Calorie Pacer (SD2008-160)
- Non-contact Biopotential Sensor (SD2008-143)
- A Duplexed Multiline Multiphoton Microscope (SD2008-074)
- Non-Invasive Method for Diagnosing and Monitoring Alzheimer’s Disease (SD2008-059)
- Ultrasensitive, Ion Channel-Based Sensors (SD2008-006)
- Universal Toy Adaptor for Children with Disabilities (SD2007-314)
- Spinal Multi-segmental Cell and Drug Delivery System (SD2007-267)
- Non-Invasive Mapping of Perfusion Territories Using MRI (SD2007-238)
- Comfortable Nasal Lavage (SD2007-207)
- Intra-Cavity Miniature Portable Visualization System For Surgery (SD2007-197)
- Ultrashort Echo Time (UTE) Spectroscopic Imaging of Tissues with Short Transverse Relaxation Time (T2) (SD2007-131)
- Method for High-Resolution MRI-Based Magnetoencephalography (MR-MEG) (SD2007-035)
- PNEUFLOW™: A Device for Increasing Tissue Blood Flow (SD2006-185)
- FlexoPred: New Tool For Protein Engineering (SD2006-123)
- A Novel Capillary Gun for Ballistic Delivery of Microscopic Particles into Tissue and Cultured Cells (SD2004-207)
- Real-Time Prediction and Prevention of Seizures (SD2004-091)
- Mental Improvement Through Magnetic Stimulation (SD2004-090)
- Portable Hand-Held Alveolar Oxygen and Carbon Dioxide Meter (SD2004-087)
- NoScar ThinFilm: A biocompatible polymer film for post-surgical scar reduction (SD2004-028)
- Hyperecho Diffusion-Weighted Magnetic Resonance Imaging (SD2003-177)
- Multiparallel Three Dimensional Optical Microscopy System (SD2003-056)
- Laser-Based Method to Induce and Image Cortical Microstrokes In-Vivo for Preclinical Analyses (SD2003-021)
- Controlled Mineralization of a Matrix (SD2002-B28)
- Improved Perfusion Imaging Using MRI with Velocity-Selective Arterial Spin Labeling Without Spatial Selectivity (SD2001-175)
- New Method for Analyzing MRI Diffusion Data (SD2001-084)
- System for Peripheral Vision Scotoma Screening (SD1999-059)
- Direct Communication by Brain Signaling (SD1999-002)
- Hydrogen Peroxide Sensing Electrode (SD1998-014)
- Control of Skeletal Muscle Fatigue During Electrical Stimulation (SD1993-303)
Antibodies
Cell Lines
Mice
Nucleic Acids
OtherResearch Reagents developed at UCSD are listed on the TechTIPS website at: Research Reagents and Cell Lines
Research Tools - Screening Assays
- Improved “One and Two Yeast Hybrid” Systems for Individually Arrayed Libraries (SD2010-069)
- Platform to Develop Treatments for “Ciliopathy" Disorders (SD2009-338)
- Monitoring Atherosclerosis Regression, Plaque Stabilization, and Cardiovascular Risk Using a Novel Method to Quantify Oxidized Phospholipids (SD2009-236)
- Compositions and Methods for Activating Toll-Like Receptors (SD2009-057)
- Compositions and Methods for Preventing and Treating Anthrax Diseases (SD2009-056)
- Analysis of Endocrine Disruption Using an Aquatic Multi-Species Microarray (SD2009-012)
- A Fragment Library for the Composition and Methods Used to Design and Develop Metallo-Enzyme Inhibitors (SD2009-022)
- Fluorescent Proteins with Increased Photostability (SD2008-123)
- A Method to Measure Neurotransmitters In Vivo (SD2007-283)
- Moldable Polycarbonate Based Biosensors (SD2007-167)
- Generation and Modulation of Cancer Stem Cells (SD2007-099)
- In Vivo Screen for Agents Affecting Erythroid Development and Disease (SD2007-090)
- The Integrin Activation Interface (SD2007-053)
- Method to Map Tertiary Chromosomal Interactions (SD2007-042)
- Digital Analysis of Gene Expression (SD2007-041)
- Method for Identifying Drug Targets Using Sequence Data (SD2007-022)
- Compounds Targeting ß-Amyloid Ion Channels for Diagnosis and Treatment of Alzheimer’s Disease (SD2007-018, SD2007-056)
- Zebrafish Model for Atherosclerosis (SD2007-014)
- Assay for Small Molecules and Defined Factors to Trigger Renewal of Cardiac Progenitors (SD2006-211)
- A Modulated Dielectrophoretic System for Ex-Vivo Diagnostics, Drug Monitoring, and Disease Management (SD2006-207)
- Compounds and Screens for Therapeutics against Tuberculosis and Other Mycobacterial Infections (SD2006-197)
- A High Throughput Assay to Identify Drug Candidates Targeting Protein Kinase A in Non-ATP Binding Sites (SD2006-160)
- Chemical Sensing by RIFTS-Reflective Interferometric Fourier-Transform Spectroscopy: A Robust, Self-Compensating Method for Label-Free Detection of Biomolecules (SD2005-179)
- Mouse Model for Macular Degeneration (SD2005-163)
- A Simple Quantitative Method To Measure Cellular Secretion (SD2005-156)
- Acid-Reactive Antibodies for Therapy and Research Applications (SD2005-142)
- Fluorescent Nucleoside Analogs That Mimic Naturally Occurring Nucleosides (SD2005-116)
- Biological Applications of "Smart Dust," or Porous Silicon Photonic Crystals (SD2005-038)
- Method to Assess Anxiolytic Properties of Therapeutic Agents (SD2004-172)
- Expression of Human CYP1A1 in Mice (SD2004-162)
- Specific Assay for the HIV-induced CD4 Down-modulation for the Screening of anti-HIV Drugs (SD2004-066)
- “Smart Dust,” or Porous Silicon Photonic Crystals (SD2004-032)
- Apparatus Enabling Microfluidic Connectivity for High Throughput Screening (SD2004-001)
- ChIP-DSL: A New Technology for Genome Mapping of Functional DNA Elements and Cellular Proteins (SD2003-244)
- Complex Optical Encoding of Porous Silicon Photonic Crystals (SD2003-214)
- Screening Method to Discover a New Candidate Therapeutic for Type II Diabetes (SD2003-202)
- Method for Generating a Progenitor Population from Postnatal Hearts (SD2003-140)
- A Method for Screening for Therapeutics for Neuropsychiatric Disorders Using a Norway Rat Model (SD2003-091)
- Novel Animal Model and Screening System for Anti-Psychotic Drugs (SD2003-089, SD2003-090)
- A Novel Genetic Method for Generating Gain-of-Function Mutations (SD2001-107)
- A Method to Inhibit I-Kappa-Beta Kinase, and Screen Drugs to Target Same (SD2000-015)
- Murine Cell lines for studing innate immunity and myeloid progenitors (SD1999-053)
- Rapid Diagnostic Assay for Cytolytic T-Cell Killing of Target Cells (SD1998-062)
- Novel Screening Method for Drugs that Modulate Transcription (SD1997-102)
- Device for Detection of Organic Compounds, Ions and Other Molecular Species by Optical Interference in a Porous Silicon Layer (SD1997-064)
- Assay of GTP/GDP Bound to RAS and Other G Proteins (SD1994-B09)
- Prognostic and Diagnostic Serum Biomarker for Cancer and Inflammatory Disease (SD1992-C06 and SD1998-C98)
- Retrovirus Detection (SD1988-B08)
Research Tools - Genomics and Related DNA / RNA Methods
- Improved “One and Two Yeast Hybrid” Systems for Individually Arrayed Libraries (SD2010-069)
- Superior Software for Designing Oligonucleotide Probe Pool: PP-Designer v2.0 (SD2009-831)
- Genetic Engineering Without Persistent Foreign Selectable Marker Genes (SD2009-358)
- An Improved Method for Whole Genome Amplification on Trace Amount (SD2009-301)
- Mostly Natural DNA Sequencing by Synthesis (SD2009-286)
- Methods and Systems for Direct Sequencing of Single DNA Molecules (SD2009-127)
- Proteins That Fluoresce in the Infrared or Generate Singlet Oxygen (SD2008-303)
- Channelrhodopsin Mutants with Improved Channel Kinetics and Other Properties (SD2008-288)
- High-Level Expression of Proteins from a Stably Segregating B. Subtilis Plasmid (SD2008-278)
- Genome-Scale Kinetic Models (SD2008-180)
- A New Approach to Medical Diagnostics and Therapeutics (SD2007-320)
- A Novel Technique for Fabricating Biomolecular Nano-Arrays Enabling High-DNA Amplification and Sequencing (SD2007-085)
- Digital Analysis of Gene Expression (SD2007-041)
- TimeSTAMP: Drug Controlled Molecular Tags for Visualizing Protein Turnover (SD2007-039)
- Uncovering the Genetic Basis of Phenotypic Change (SD2007-024)
- Genome-Scale Reconstruction of Human Metabolism (SD2006-294)
- Methods for High Sensitivity Detection of Deletions from Genomic DNA (SD2006-249)
- Method and System for Rapid Construction and Screening of Functional, Tagged, Fusion Proteins (SD2006-094)
- A Novel Method to Predict the Response to Lithium Treatment (SD2006-070 and SD2008-101)
- In Vitro Method to Improve Transfection Efficiency with In Vivo Applicability (SD2005-251)
- Chemical Sensing by RIFTS-Reflective Interferometric Fourier-Transform Spectroscopy: A Robust, Self-Compensating Method for Label-Free Detection of Biomolecules (SD2005-179)
- "Smart Dust,” or Porous Silicon Photonic Crystals (SD2004-032)
- ChIP-DSL: A New Technology for Genome Mapping of Functional DNA Elements and Cellular Proteins (SD2003-244)
- Complex Optical Encoding of Porous Silicon Photonic Crystals (SD2003-214)
- Determination of Protein Size (SD2003-182)
- Method for Automated Injection of Drosophila Embryos (SD2002-167)
- Novel Recyclable Silylation Reagent for Use in Generating Protecting Groups in Large-Scale Oligonucleotide Manufacture (SD2002-164)
- Laser-Mediated Automated Tissue Sectioning and In Situ Localization of Proteins and mRNA (SD2002-116)
- Whole-Proteome Interaction Mining: Computational Approach (SD2002-033)
- Novel Single Nucleotide Polymorphisms (SNPs) Associated with Hypertension (SD2001-215)
- Method for Predicting Protein Binding from Primary Structure Data (SD2001-034)
- Automated Cell and Tissue Extraction and Solid Phase Capture Device (SD2001-007)
- Gene Targets for Neuropsychiatric Disorders (SD2000-094)
- Time-saving Method for Solid Phase Isolation of Proteins, Nucleic Acids and Other Macromolecules (SD1998-108)
- Device for Detection of Organic Compounds, Ions and Other Molecular Species by Optical Interference in a Porous Silicon Layer (SD1997-064)
- Recombinant Luciferase Gene, Luciferase Fusion Proteins and Methods of Use (SD1984-C05)
Research Tools - Proteomics and Related Protein Methods
- A Superior Method for High-Level Production of Recombinant Protein (SD2009-147)
- Protein Biomarkers for Diagnosis and Treatment of Chronic Lymphocytic Leukemia (CLL) (SD2009-033)
- Large-Scale Quantitative Phosphoproteome Profiling (SD2008-267)
- Genome-Scale Kinetic Models (SD2008-180)
- New Tools for Protein Functional Site Characterization (SD2007-112)
- Method for Identifying Drug Targets Using Sequence Data (SD2007-022)
- Method for Identification of Peptides and Post-Translational Modifications (SD2006-162 and SD2006-817)
- Genome-Scale Reconstruction of Human Metabolism (SD2006-294)
- Active Microelectronic Array for Massively Parallel Peptide Synthesis and Binding Constant Analysis (SD2006-208)
- In vivo Protein Labeling (SD2005-272)
- Chemical Sensing by RIFTS-Reflective Interferometric Fourier-Transform Spectroscopy: A Robust, Self-Compensating Method for Label-Free Detection of Biomolecules (SD2005-179)
- Biological Applications of "Smart Dust," or Porous Silicon Photonic Crystals (SD2005-038)
- Predicted Ligands for Binding Orphan G-Protein-Coupled Receptors and Method Therefore (SD2004-148)
- “Smart Dust,” or Porous Silicon Photonic Crystals (SD2004-032)
- Chemical Tools for Analysis and Manipulation of Enzymes in Biosynthetic Proteomes (SD2003-226)
- Complex Optical Encoding of Porous Silicon Photonic Crystals (SD2003-214)
- Determination of Protein Size (SD2003-182)
- Digital Molecular Sensor (SD2003-060)
- The Use Of Deuterium Exchange-Mass Spectrometry To Enhance Large-Scale Protein Crystallographic Structure Determination (SD2002-157)
- Laser-Mediated Automated Tissue Sectioning and In Situ Localization of Proteins and mRNA (SD2002-116)
- Whole-Proteome Interaction Mining: Computational Approach (SD2002-033)
- CE-Combinatorial Extension (SD2001-155)
- Method for Predicting Protein Binding from Primary Structure Data (SD2001-034)
- Fluorescent Tagged Synaptic Proteins as Models for Neurodegenerative Disorders (SD2001-019)
- Automated Cell and Tissue Extraction and Solid Phase Capture Device (SD2001-007)
- The Total Synthesis of Monatin (SD2000-175)
- Method to Quantitate Oxidized LDL Epitope Content (2000-062)
- Time-saving Method for Solid Phase Isolation of Proteins, Nucleic Acids and Other Macromolecules (SD1998-108)
- Device for Detection of Organic Compounds, Ions and Other Molecular Species by Optical Interference in a Porous Silicon Layer (SD1997-064)
- Protein Recruitment System (SD1996-001)
- Recombinant Luciferase Gene, Luciferase Fusion Proteins and Methods of Use (SD1984-C05)
Research Tools - Bioinformatics
- Mostly Natural DNA Sequencing by Synthesis (SD2009-286)
- A Powerful Computational Approach to Identify Surface of Protein-Protein Interaction (SD2009-193)
- Methods and Systems for Direct Sequencing of Single DNA Molecules (SD2009-127)
- A Method to Generate Novel Bioactive Molecules (SD2008-230)
- Method and Formalism to Reconstruct Transcriptional and Translational Stoichiometric Networks for Organisms (SD2008-225)
- De Novo Sequencing and Dereplication of Cyclic Nonribosomal Peptides (SD2008-183)
- HESA: Hepatic Encephalopathy Screening Algorithm (SD2007-804)
- Method for Computing the Number of Peptide Reconstructions of Tandem Mass Spectra (SD2007-293)
- New Tools for Protein Functional Site Characterization (SD2007-112)
- A Novel Technique for Fabricating Biomolecular Nano-Arrays Enabling High-DNA Amplification and Sequencing (SD2007-085)
- TimeSTAMP: Drug Controlled Molecular Tags for Visualizing Protein Turnover (SD2007-039)
- Method for Identifying Drug Targets Using Sequence Data (SD2007-022)
- PepNovo (SD2006-834)
- Genome-Scale Reconstruction of Human Metabolism (SD2006-294)
- Method for Assembly and De-Novo Sequencing of Tandem Mass Spectra from Overlapping Peptides(SD2006-265)
- Novel Algorithms and Software for Mapping Complex Networks (SD2006-258)
- FlexoPred: New Tool For Protein Engineering (SD2006-123)
- Euler V2.0 (SD2004-827)
- Predicted Ligands for Binding Orphan G-Protein-Coupled Receptors and Method Therefore (SD2004-148)
- Digital Molecular Sensor (SD2003-060)
- Protein Kinase Resource (PKR) (SD2003-801)
- Whole-Proteome Interaction Mining: Computational Approach (SD2002-033)
- CKAAPS DB: A Conserved Key Amino Acid Positions Database (SD2002-826)
- CE-Combinatorial Extension (SD2001-155)
- Method for Predicting Protein Binding from Primary Structure Data (SD2001-034)
- CE-Combinatorial Extension Algorithms and Computer Programs for Comparing the 3-Dimensional Structures of Protein Molecules (SD2001-155)
- Biostar: Molecular Biology Annotation and Dissemination Tool (SD2001-815)
- MC-CE - Monte Carlo Combinatorial Extension, Algorithms & Computer Programs for Comparing and Aligning Multiple 3-D Structures of Protein Molecules (SD2001-816)
Research Tools - Other Software
- New Antiviral Compounds Active Against Avian Influenza N1 (SD2008-170)
- Method for Identifying Drug Targets Using Sequence Data (SD2007-022)
- Novel Algorithms and Software for Mapping Complex Networks (SD2006-258)
- Simulation-Based Probabilistic Assessment of Chromosome Segment Sharing in Arbitrary Geneologies (SD2004-164)
- Clinical Trials Management System (SD2004-082)
- GenePalette: Software For Genome Sequence Navigation And Analysis (SD2002-853)
- Splicing Graph Genome Assembler Software Modules - EULER-TC (SD2002-822)
- Splicing Graph Genome Assembler Software Modules - EULER-PCR (SD2002-821)
- Splicing Graph Genome Assembler Software Modules - EULER-EC (SD2002-820)
- Splicing Graph Genome Assembler Software Modules - EULER-Connect (SD2002-819)
- Splicing Graph Genome Assembler Software Modules - EULER-Compare (SD2002-818)
- FADE and PADRE (SD2002-817)
- Open MMS (SD2002-814)
- The MEME/MAST System Motif Discovery and Research Version 3.0 (SD2002-802)
- In Vivo Imaging of Inflammation and Reactive Oxygen Species: Compounds and Methods (SD2009-324)
- A New Palladium Catalyst System (SD2009-275)
- High-Speed Laser Interference Structured Illumination Microscopy (SD2009-221)
- Improved Labeling of Nerves (SD2009-220)
- High-Speed Plasmonic Structured Illumination Microscopy (SD2009-202)
- A Method for Increasing Wound Healing and Controlling Hyperproliferative Cutaneous Diseases (SD2009-030)
- Selective Partitioning of Cell Populations and Molecules In Vitro and In Vivo (SD2008-106)
- Non-Invasive Method for Diagnosing and Monitoring Alzheimer’s Disease (SD2008-059)
- Dendrimer Modified Oligonucleotides for High Yield Singly Modified Nanoparticle Probes (SD2007-037)
- Uncovering the Genetic Basis of Phenotypic Change (SD2007-024)
- A Modulated Dielectrophoretic System for Ex-Vivo Diagnostics, Drug Monitoring, and Disease Management (SD2006-207)
- Polyamine Ligands for Use as Metalloproteinase Inhibitors (SD2006-069)
- High-Throughput Functional Evaluation of Mouse Phenotype (SD2005-201)
- Multipotent Amniotic Fetal Stem Cells: A Novel Source of Human Stem Cells (SD2005-041)
- Animal Model to Detect the Presence of Environmental Toxicants (SD2004-144)
- Clinical Use of Ultrashort TE Pulse Sequences in MRI (SD2004-056)
- A Novel Image Reconstruction Algorithm for MRI Data Sets (SD2003-219)
- Robust Image Reconstruction Software for Phased Array Coil Data in MRI (SD2003-183)
- Improved Fluorescent Molecular Rotors for Viscosity Measurement in Small Volumes (SD2003-145)
- Combinatorial Transcription Control (SD2003-087)
- Multiparallel Three Dimensional Optical Microscopy System (SD2003-056)
- A New Construct for Creating Conditional Knock-Outs in Mice (SD2003-037)
- Method for Fast Atomic Density Evaluation (SD2003-027)
- New Medical Coding/Billing Tools for Physicians and Coders (SD2002-811)
- The MEME/MAST System Motif Discovery and Research Version 3.0 (SD2002-802)
- Laser-Mediated Automated Tissue Sectioning and In Situ Localization of Proteins and mRNA (SD2002-116)
- Multi-Potent Central Nervous System (CNS) Stem Cells (SD2001-052)
- Automated Nociception Analyzer/Flinch Monitor (SD1998-024)
- Methods for the Detection of BCR-ABL and Abnormal ABL Proteins in Leukemia Patients (SD1990-C65)
- Recombinant Luciferase Gene, Luciferase Fusion Proteins and Methods of Use (SD1984-C05)
Bioengineering - BioChips and BioMEMs
- Active Microelectronic Array for Massively Parallel Peptide Synthesis & Binding Constant Analysis (SD2006-208)
- Novel Bio-sensor Platform Based on Surface Enhanced Raman Scattering (SERS) Chip (SD2006-067_SERS Chip Bundle)
- Chemical Sensing by RIFTS-Reflective Interferometric Fourier-Transform Spectroscopy: A Robust, Self-Compensating Method for Label-Free Detection of Biomolecules (SD2005-179)
- Arrays for Functional Genomics/High Throughput Phenotyping (SD2001-085)
- Micropatterning Polyethylene Oxide (SD2001-001)
- Advanced Acrylic Orthopedic Cements (SD1993-206)
Bioengineering - Cell Culture and Tissue Engineering
- Online Regression Method for Prediction with Application to Image and Video Coding (SD2008-039)
- Article Comprising Subcutaneous Hepatocyte Transplants, Fabrication Process Thereof, and Therapeutic Method Using Such Transplants (SD2007-202)
- Simple Method for Deriving Germ Cells, Male Gametes and Supporting Sertoli-Like Cells from Human Embryonic Stem Cells (SD2007-179)
- A Modulated Dielectrophoretic System for Ex-Vivo Diagnostics, Drug Monitoring, and Disease Management (SD2006-207)
- Biological Applications of "Smart Dust," or Porous Silicon Photonic Crystals (SD2005-038)
- Artificial Bone from Sea Shells (SD2005-022)
- “Smart Dust,” or Porous Silicon Photonic Crystals (SD2004-032)
- Self-Assembling, Self-Orienting Photonic Crystals of Porous Silicon (SD2003-257)
- Complex Optical Encoding of Porous Silicon Photonic Crystals (SD2003-214)
- Determination of Protein Size (SD2003-182)
- Use of Steady-State Oxygen Gradients to Modulate Cell Functions (SD2003-173)
- Method for 3D Cell Patterning Within Hydrogel Scaffolds (SD2003-035)
- Optically Encoded Nanoparticles (SD2002-075)
- Inhibition of a Novel MAP Kinase Complex to Reduce Joint Destruction and Inflammation (SD2002-205)
- Methods to Preserve Distinctive Characteristics of Engineered Articular Cartilage (SD2001-214)
- Methods of Tissue Repair, Regeneration, and Tissue Engineered Compositions (SD2001-205)
- Nanoporous Silicon Bioreactor (SD2001-054)
- Ex vivo Preparation of Kidney Tissue (SD1999-141)
- Novel Methods for Increasing Peripheral Blood Circulation (SD1997-098)
- Device for Detection of Organic Compounds, Ions and Other Molecular Species by Optical Interference in a Porous Silicon Layer (SD1997-064)
- Responsive Microbubbles for Ultrasound Contrast Enhancement (SD2009-326)
- Low-Cost, High-Throughput Nanoscale Patterning of DNA (SD2009-274)
- A Hyaluronan-Based Nanoparticle Cisplatin Delivery System (SD2009-190)
- Chromatography for Diet and/or Nutrition/Chemical Control (SD2009-050)
- Nanoparticles for Targeted, In Vivo Delivery of Diverse Drug Chemotypes (2009-032)
- Ultrasensitive, Ion Channel-Based Sensors (SD2008-006)
- pH-"Tunable" Nano-Particle Drug Delivery System (SD2006-140)
- Chemical Sensing by RIFTS-Reflective Interferometric Fourier-Transform Spectroscopy: A Robust, Self-Compensating Method for Label-Free Detection of Biomolecules (SD2005-179)
- Self-Assembling 2D and 3D Nanostructures for Nano-Photonic and Nano-Electronic IC's and Devices (SD2005-133)
- Porous Photonic Crystals for Intraocular Drug Delivery (SD2005-088)
- Biological Applications of "Smart Dust," or Porous Silicon Photonic Crystals (SD2005-038)
- A Method to Detect and Treat Localized Abnormalities (SD2004-251)
- “Smart Dust,” or Porous Silicon Photonic Crystals (SD2004-032)
- Self-Assembling, Self-Orienting Photonic Crystals of Porous Silicon (SD2003-257)
- Complex Optical Encoding of Porous Silicon Photonic Crystals (SD2003-214)
- Nanostructured Casting of Organic and Biopolymers in Porous Silicon Templates (SD2003-024)
- Determination of Protein Size (SD2003-182)
- Optically Encoded Nanoparticles (SD2002-075)
- Controlled Mineralization of a Matrix (SD2002-B28)
- Nanoporous Silicon Bioreactor (SD2001-054)
- Device for Detection of Organic Compounds, Ions and Other Molecular Species by Optical Interference in a Porous Silicon Layer (SD1997-064)
- Compositions and Methods for Preventing and Treating Anthrax Diseases (SD2009-056)
- Biological Applications of "Smart Dust," or Porous Silicon Photonic Crystals (SD2005-038)
- “Smart Dust,” or Porous Silicon Photonic Crystals (SD2004-032)
- Self-Assembling, Self-Orienting Photonic Crystals of Porous Silicon (SD2003-257)
- Complex Optical Encoding of Porous Silicon Photonic Crystals (SD2003-214)
- Determination of Protein Size (SD2003-182)
- Biosensor for nerve agents and pesticides (SD2002-159)
- Optically Encoded Nanoparticles (SD2002-075)
- Device for Detection of Organic Compounds, Ions and Other Molecular Species by Optical Interference in a Porous Silicon Layer (SD1997-064)
- Delivery of Therapeutically Relevant Macromolecules Using pH-Sensitive Peptide Transduction Linkages (SD2009-296)
- A New Palladium Catalyst System (SD2009-275)
- High Glucose Uptake E. Coli Strain (SD2009-238 and SD2009-239)
- Transducible Delivery of Nucleic Acids Using Modified dsRNA Binding Domains (SD2009-213)
- Oxygen Independent E. Coli (SD2009-158)
- Analysis of Endocrine Disruption Using an Aquatic Multi-Species Microarray (SD2009-012)
- A Method of Developing Single Molecule DNA Nanoparticles as Diagnostic and
Therapeutic Agents (SD2008-237) - Genome-Scale Kinetic Models (SD2008-180)
- Simple Method for Deriving Germ Cells, Male Gametes and Supporting Sertoli-Like Cells from Human Embryonic Stem Cells (SD2007-179)
- Moldable Polycarbonate Based Biosensors (SD2007-167)
- Uncovering the Genetic Basis of Phenotypic Change (SD2007-024)
- Genome-Scale Reconstruction of Human Metabolism (SD2006-294)
- Active Microelectronic Array for Massively Parallel Peptide Synthesis & Binding Constant Analysis (SD2006-208)
- A High Throughput Assay to Identify Drug Candidates Targeting Protein Kinase A in Non-ATP Binding Sites (SD2006-160)
- Isolated PTPMT1 Protein Which Mediates Insulin Production (SD2005-243)
- Chemical Sensing by RIFTS-Reflective Interferometric Fourier-Transform Spectroscopy: A Robust, Self-Compensating Method for Label-Free Detection of Biomolecules (SD2005-179)
- Lectin Type Fold as a Scaffold for Massive Sequence Variation (SD2005-108)
- Biological Applications of "Smart Dust," or Porous Silicon Photonic Crystals (SD2005-038)
- Transport Molecules from Dendritic Oligo-Guanidines (SD2003-144, SD2002-042)
- Method for Treatment and Prevention of Physiological Shock (SD1999-097)
- Disease Treatments Using Multimeric TNFSF Ligands (SD1999-003)
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