Biomedical Technologies

• These technologies include (not limited to):
  
  • Therapeutics & Pharmaceuticals
    
    • Cancer
    • Cardiovascular
    • CNS Disease
    • Dermatological, Opthalmological, Otological Diseases
    • Endocrine / GI Diseases
    • Infectious Diseases
    • Inflammation and Immune Diseases
    • Respiratory Diseases
    • Urological Diseases
    • Other
      
  • Stem Cells
  • New Chemical Entities, Drug Leads
  • Delivery Systems
  • Diagnostics
  • Medical Devices
  • Research Reagents
  • Research Tools
    
    • Screening Assays
    • Genomics and Related DNA / RNA Methods
    • Proteomics and Related Protein Methods
    • BioInformatics
    • Other Software
    • Other Tools
      
  • Bioengineering
    
    • BioChips & BioMEMS
    • Cell Culture and Tissue Engineering
      
  • Nanobiotechnologies
  • Homeland Security
  • Platform technologies

Case Listing (Or search via keyword using the search feature at the top of the menu bar).

Therapeutic Areas - Cancer

• Predictive Biomarkers for Metastatic Potential in Breast Cancer (SD2008-084)
• Cancer Therapy Method (SD2008-018)
• Compounds Targeting Misregulated Protein Kinases (SD2008-009)
• Selective targeting and depletion of specific lymphocyte cell populations in vivo (SD2007-329)
• Augmenting antigen-specific T cell responses following vaccination using IL-7 cytokine complexes (SD2007-327)
• Modification of IL-1 enhances biological activity and creates a potent vaccine adjuvant (SD2007-324)
• Comprehensive Pharmacogenetic Approach to the Diagnosis and Treatment of Cancer (cancer bundle/SD2007-cancer)
• In Vivo Model for Hematopoietic and Cancer Stem Cell Development (SD2007-241)
• Cytokines Complexes for the Treatment of Preexisting Tumors (SD2007-227)
• Methods to inhibit the emergence or progression of hepatocellular carcinoma with estrogens or estrogen-like compounds (SD2007-190)
• Methods to make the early detection of hepatocellular carcinoma; methods to inhibit the emergence or progression of hepatocellular carcinoma (SD2007-189)
• Methods to Inhibit the Emergence of Metastatic Prostate Cancer (SD2007-141)
• Mechanism of Pain Relief In Diabetes By Prosaptide TX14(A) (SD2007-099)
• Novel Screen for Agents affecting Normal and Malignant Blood Cell Development (SD2007-090)
• Novel Small Molecules, Gambogic Acid Analogues, As AntiCancer Agents (SD2007-082)
• New Derivatives of Pyrone, Hydroxypyridinone, and Hydroxypyridinethione (SD2007-058)
• Method of diagnosing and treating uterine fibroids (SD2006-297)
• Oral Drug for Stimulation of Erythropoietin Levels in Anemic Patients (SD2006-267)
• Methods for High Sensitivity Detection of Deletions from Genomic DNA (SD2006-249)
• Transducible Delivery of siRNAs by dsRNA Binding Domain Fusions to PDT/CPPs (SD2006-150)
• A Novel Method to Inhibit Lymphangiogenesis and Tumor Metastasis(SD2006-143)
• pH-“Tunable” Nano-particle Drug Delivery System (SD2006-140)
• Identifying Critical Pathways in Cancer and Metastasis (SD2006-131)
• Compositions and Methods for Therapeutic Cancer Vaccines (SD2006-095)
• Natural Products for Cancer Therapeutics (SD2006-079)
• Polyamine Ligands for Use as Metalloproteinase Inhibitors (SD2006-069)
• Methods to Detect and Treat Prostate, Breast and Other Hormone-Dependent Cancers (SD2005-274)
• Compositions and Methods to Enhance the Immune Response (SD2005-252)
• Treatment and Diagnosis of Chronic Lymphocytic Leukemia (CLL), Breast Cancer, and Other Cancers through Use of a Monoclonal Antibody (SD2005-212)
• Method for Generating Unlimited Numbers of Macrophage/Dendritic Cells and Neutrophils (SD2005-114)
• Novel Markers for the Treatment and Diagnosis of Chronic Lumphocytic Leukemia (CLL) (SD2005-082)
• A bispecific molecule comprised of a GRP-R ligand and a monoclonal antibody to CD3 (SD2005-080)
• Apoptosis Inhibitors (SD2005-E50)
• Treatment for Type II Diabetes and Cancer by Regulating Glucose Transporter Levels (SD2004-243)
• Osmotic Stress and Human Disease (SD2004-155)
• Adenovirus Vector Encoding Human GD40 (SD2004-163)
• Superactive p53 (SD2004-160)
• Mice Lacking IKK Beta in Intestinal Epithelial Cells (SD2004-133)
• Novel Matrix Metalloproteinase Inhibitors (SD2004-102)
• New Anticancer Target (SD2004-088)
• In vivo Propagated Murine A20 Lymphoma Cells (SD2004-085)
• Novel Method to Inhibit Tumor Growth & Other Neovascular Diseases (SD2004-076)
• Oligonucleotides for the Treatment of Cancer and Autoimmune Diseases (SD2004-013)
• Regulating genes in the COX-2 pathway for colon cancer (SD2003-261)
• Chemical Tools for Analysis and Manipulation of Enzymes in Biosynthetic Proteomes (SD2003-226)
• Chronic Lymphocytic Leukemia B Cells (SD2003-185)
• New Uses for Inhibitors of Inosine Monophosphate Dehydrogenase (SD2002-C35)
• New Therapy for Solid Tumors and other Neovascular Diseases (SD2002-241)
• Novel therapeutic approach for cancer, fibrosis and auto-immune disorders (SD2002-149)
• Targeted Cancer Therapy (SD2002-020)
• Novel Markers and Gene Targets useful for the Diagnosis and Suppression of Metastasis (SD2002-005)
• A Novel Method to Detect and Inhibit Angiogenesis (SD2001-135)
• Target for Development of Inhibitors of Cancer (SD2001-134)
• Treatment of Cancer by Inducing Cell Apoptosis (SD2001-030)
• ISS-Receptor as a Drug Discovery Tool (SD2000-C22)
• A New Strategy for Leukemia Therapy (SD2000-159)
• Disease Treatments Using Multimeric TNFSF Ligands (SD1999-003)
• A Method to Induce CTL Response in Immune Deficient Patients (SD1999-A77)
• Diagnosis of Cancers with Metastatic Potential (SD1998-D00)
• Method for Early Diagnosis and Determination of Prognosis in Cancer (SD1998-B84)
• Diatom Nitrate Transporter Transgene Promoting Plant Growth on Low Nitrate Soils (SD1998-083)
• Selectin Inhibition: Novel Uses For An Already Approved Drug (SD1998-049)
• Prosaposin: Therapeutic compound for p revention and treatment of pain (SD1995-177)
• Diagnostic Test for Cancer Susceptibility (SD1994-A91)
• Transcription Factor for the Regulation of Skin and Hair Development (SD1993-A27)
• Method for Selective Methionine Starvation of Malignant Cells (SD1992-C83)
• Prognostic and Diagnostic Serum Biomarker for Cancer and Inflammatory Disease (SD1992-C06 and SD1998-C98)
• Identification and Use of Vascular Surface Molecules for Disease Diagnosis and Treatment (SD1992-A32)

Therapeutic Areas - Cardiovascular Diseases

• Method for Identification of Novel Anti-hypertensives (SD2008-007)
• Novel Methods to Predict New Cardiovascular Events by Measuring Oxidized Phospholipids (OxPL), Lipoprotein (a) and Lipoprotein-Associated Phospholipase A2 Mass and Activity (Lp-PLA2) and Novel High-Throughput Assay to Quantitate Lp-PLA2 on Lipoprotein (a) and Apolipprotein B-100 Particles to Determine Cardiovascular Risk (SD2007-261)
• A novel nitric-oxide releasing drug (SD2007-196)
• Cardioprotective Effects of Catestatin (SD2007-118)
• Method for Discovering Agents that Limit Vascular Leak by Strengthening Cell-Cell Junctions (SD2007-070)
• New Derivatives of Pyrone, Hydroxypyridinone, and Hydroxypyridinethione (SD2007-058)
• Atheroprotective Vaccine (SD2006-250)
• New Target for Cardiovascular Disease and Diabetes (SD2005-165)
• Enhanced Expression of TRP Channels in IPAH (SD2005-073)
• A Novel Index of Assessing Atherosclerosis Regression and Plaque Stabilization (SD2005-037)
• CaMKII Heart Failure and Arrythmic Mice (SD2004-125)
• Novel Matrix Metalloproteinase Inhibitors (SD2004-102)
• A Practical Vaccine for Protection Against Atherosclerosis (SD2003-208)
• Method for Generating a Progenitor Population from Postnatal Hearts (SD2003-140)
• Use of Calcium Binding Proteins to Improve Cardiac Contractile Function. (SD2002-225)
• Novel Single Nucleotide Polymorphisms (SNPs) Associated with Hypertension (SD2001-215)
• C5 Epimerase for Use in Polysaccharide Production (SD2001-192)
• ISS-Receptor as a Drug Discovery Tool (SD2000-C22)
• Method to Quantitate Oxidized LDL Epitope Content (2000-062)
• Assessing Risk for Arterial Calcification (SD1999-C79)
• Cell Activation Factor (1998-076)
• Novel Recombinant Adenovirus Vectors for Tissue-Specific Gene Expression in Heart (1998-045)
• In Vivo Gene Therapy for Heart Failure (SD1998-B28)
• Blood Plasma Viscosity and Tissue Perfusion: Blood Plasma Extenders (1997-098)

Therapeutic Areas - CNS Diseases

• Transplantation of Human Neural Cells for Treatment of Neurodegenerative Conditions (SD2008-210)
• Use of Anti-Inflammatory Strategies to Treat Psychosis, Delirium, and Cognitive Impairment (SD2008-114)
• Compositions and Methods for Diagnosing Alzheimer's Disease (SD2008-095)
• HESA: Hepatic Encephalopathy Screening Algorithm (SD2007-804)
• A Method to Measure Neurotransmitters In Vivo (SD2007-283)
• Structure Based Design of Anti-Parkinson’s Disease Compounds Targeting Synuclein Oligomerization (SD2007-274)
• Treatment of Multiple Sclerosis and spinal cord injury through use of 2-oxoamide phospholipase A2 inhibitors (SD2007-145)
• Development of a specific inhibitor for PDE4A4: therapeutic implications in pulmonary disease and nerve regeneration (SD2006-245)
• Lead Compounds for Diagnosis and Therapy of Alzheimer's Disease (SD2006-105)
• Improved Treatment for Cystinosis and Neurodegenerative Disorders (SD2006-092)
• Biomarker for Neurodegenerative and Demyelinating Disease (SD2006-086)
• Method to Predict Treatment Response in Generalized Social Phobia (2006-021)
• Enhancing Neural Recovery Following Stroke or Brain Injury (SD2006-019)
• Blocking Fibrin/Mac-1 Interaction as a Therapeutic Target for Multiple Sclerosis and Other Neuroinflammatory Diseases (SD2006-001)
• New Approach for Therapeutics for Alzheimer's Disease (SD2005-261)
• New Method for Promoting Nerve Regeneration (SD2005-155)
• Prion Protein Infection, Protection and Treatment (SD2005-004)
• Treatment for Mental Illness Through Manipulation of Neurotransmitter Profile (SD2004-218)
• Novel Therapeutic Approach for the Treatment of Autism Spectrum Disorders (SD2004-215)
• Novel Anxiolytic Target (SD2004-104)
• Gene Therapy for Usher Syndrome Type 1B (SD2004-074)
• NoScar ThinFilm: A biocompatible polymer film for post-surgical scar reduction (SD2004-028)
• Novel Animal Model and Screening System for Anti-Psychotic Drugs (SD2003-089, SD2003-090, SD2003-091)
• Phosphatases that Regulate Gene Transcription (SD2003-061)
• Laser-Based Method to Induce and Image Cortical Microstrokes in-vivo for Preclinical Analyses (SD2003-021)
• Detection and treatment of Alzheimer's Disease (SD2002-161)
• Use of Neurotrophic Factors in Treating Memory Loss and Neurodegenerative Disease (SD2001-109)
• Erythropoietin and Erythropoietin Receptors in the Peripheral Nervous System (SD2001-090)
• Multi-Potent Central Nervous System Stem Cells (SD2001-052)
• ISS-Receptor as a Drug Discovery Tool (SD2000-C22)
• Gene Targets for Neuro-psychiatric Disorders (SD2000-126 & SD2000-094)
• Human Methods and Use of CNS Cell Lines (SD1998-A34)
• Regulatable retrovirus system for genetic modification of cells (SD1996-B05)
• Prosaposin: Therapeutic compound for p revention and treatment of pain (SD1995-177)
• Method for Production of Neuroblasts (SD1992-B16)

Therapeutic Areas - Dermatological, Opthalmological, Otological Diseases

• Device and Method to Store and Implant the Corneal Graft in DSAEK (SD2008-202)
• Small Molecule Kinase Inhibitors to Prevent Neoangiogenesis and Macular Degeneration (SD2008-152)
• TNF-alpha Inhibitor to Suppress Inflammation Without Suppressing the Innate Immune Response (SD2008-129)
• Adaptive Eyeglass Lens for Correction of Presbyopia (SD2008-015)
• Vaccines against acne and acne-associated diseases (SD2007-264)
• Prevent or Treat Skin and Wound Infections With A New Antimicrobial Peptide (SD2007-184)
• Therapeutic Modulation of Ocular Surface Boundary Lubrication (SD2007-168)
• New Treatment or Diagnosis for Rosacea with Existing Approved Drugs (SD2007-047)
• Enhance Wound Repair Using an Existing Approved Drug (SD2006-075)
• Mouse Model for Macular Degeneration (SD2005-163)
• Porous Photonic Crystals for Intraocular Drug Delivery (SD2005-088)
• Means to detect, treat and prevent sensorineural hearing loss (SD2004-004)
• Anti-viral and anti-microbial peptides (SD2003-079, SD2003-114 and SD2004-043)
• Lipids for Local Eye Therapy for Diseases (SD2003-113)
• Broad Spectrum Natural Protein Antibiotic (SD2002-119)
• Enhanced Photodynamic Therapy in Age-Related Macular Degeneration (SD2001-200)

Therapeutic Areas - Endocrine / GI Diseases

• Immunizations Preventing Insulin Resistance (SD2008-037)
• Method for Treatment and Prevention of Physiological Shock (SD2007-234)
• Method to Image and Detect Islet Beta Cells Using Cell-surface Proteins (SD2005-224)
• Acid-Reactive Antibodies for Therapy and Research Applications (SD2005-142)
• Treatment for Type II Diabetes and Cancer by Regulating Glucose Transporter Levels (SD2004-243)
• Mouse Model of Crohn’s Disease and Method to Develop Specific Therapeutics (SD2004-154)
• DNA:GST-AtNOS1 Plasmid (SD2004-143)
• Treatment for Diabetic Cardiomyopathy (SD2004-071)
• Irradiated Probiotic for Inflammatory Bowel Disease (SD2003-C32)
• Novel, validated target for type II Diabetes drug inhibitors (SD2003-238)
• Treatment of Lactic Acidosis Associated with Biguanide Anti-diabetic Usage (SD2003-193)
• Phosphatases that Regulate Gene Transcription (SD2003-061)
• Treatment of Liver Fibrosis by Induction of Stellate Cell Apoptosis (SD2001-024)
• Method for treatment and prevention of physiological shock (SD1999-097)
• Prevention of Liver Fibrosis in Hepatitis by Inhibition of Stellate Cell Activation (96-064)
• Prosaposin: Therapeutic compound for p revention and treatment of pain (SD1995-177)

Therapeutic Areas - Infectious Diseases

• Method for Identifying A Bacterial Toxin and Strategy for Vaccine Development (SD2008-211)
• Immunostimulatory Sequences and Vectors for Inflammatory and Infectious Diseases (technology bundle)
• Mitigating the Lethal Coagulopathy of Sepsis (SD2008-113)
• Augmenting antigen-specific T cell responses following vaccination using IL-7 cytokine complexes (SD2007-327)
• Modification of IL-1 enhances biological activity and creates a potent vaccine adjuvant (SD2007-324)
• New Treatment for Anthrax Infection (SD2007-321)
• Vaccines against acne and acne-associated diseases (SD2007-264)
• Prevent or Treat Skin and Wound Infections With A New Antimicrobial Peptide (SD2007-184)
• Novel Screen for Agents affecting Normal and Malignant Blood Cell Development (SD2007-090)
• Uncovering the Genetic Basis of Phenotypic Change (SD2007-024)
• Oral Drug for Stimulation of Erythropoietin Levels in Anemic Patients (SD2006-267)
• Compounds and Screens for Therapeutics against Tuberculosis and other Mycobacterial Infections (SD2006-197)
• Transducible Delivery of siRNAs by dsRNA Binding Domain Fusions to PDT/CPPs (SD2006-150)
• New Vaccine for Persistent Viruses (SD2006-121)
• Enhance Wound Repair Using an Existing Approved Drug (SD2006-075)
• Polyamine Ligands for Use as Metalloproteinase Inhibitors (SD2006-069)
• Treatment of intestinal animal parasitic diseases in veterinary and human medicine (SD2006-049)
• Compositions and Methods to Enhance the Immune Response (SD2005-252)
• Novel Alkoxyalkyl Phosphate Derivatives of Nucleoside Phosphonates with Antiviral Activity. (SD2005-175)
• Novel Target for Methicillin Resistant Staph aureus (MRSA) (SD2005-166)
• Acid-Reactive Antibodies for Therapy and Research Applications (SD2005-142)
• Derivatives of Novel Nucleoside Phosphonates with Anti-viral Activity (SD2005-105)
• A new nucleoside phosphonate analog with antiviral activity (SD2004-257)
• Monoclonal Antibodies Immunoreactive with Lipolysaccharide Binding Protein (LBP) and Methods of Their Use (SD2004-221)
• Interference with the Virus-Induced CD4 Down-Modulation as an Anti-HIV Approach (SD2004-111)
• New Derivatives of Phosphonate Compounds with Enhanced Anti-viral Activity. (SD2004-100)
• Treatment of intestinal animal parasitic diseases in veterinary and human medicine (SD2004-035)
• Vaccines and Diagnostics Using the Native Capsule of Group B Streptococcus (SD2004-027)
• Irradiated Bacterial Vaccine to Induce Broad Immune Response (SD2004-B86)
• Synthetic Peptide for Treating and Preventing Macrophage Death Induced by Anthrax Toxin (SD2003-174)
• Targets for the development of anti-actinomycete drugs and vaccines (SD2003-073)
• New Uses for Inhibitors of Inosine Monophosphate Dehydrogenase (SD2002-C35)
• A target for development of anti-actinomycete drugs and vaccines (SD2002-175)
• Novel Compounds for the Development of TB Therapeutics (SD2001-169)
• ISS-Receptor as a Drug Discovery Tool (SD2000-C22)
• ISS is a Chemotherapeutic Agent for Mycobacterial Infections (SD2000-B58)
• A target for development of anti-actinomycete drugs and vaccines (SD2000-164)
• A Method to Induce CTL Response in Immune Deficient Patients (SD1999-A77)
• Complementary Screens for the Development of Tuberculosis Drugs and Vaccines (1999-156)

Therapeutic Areas - Inflammation & Immune Diseases

• Targeting upstream kinase MKK3 for pain (SD2008-061)
• Immunostimulatory Sequences and Vectors for Inflammatory and Infectious Diseases (technology bundle)
• Selective targeting and depletion of specific lymphocyte cell populations in vivo (SD2007-329)
• Augmenting antigen-specific T cell responses following vaccination using IL-7 cytokine complexes (SD2007-327)
• Modification of IL-1 enhances biological activity and creates a potent vaccine adjuvant (SD2007-324)
• New use for existing drug to treat rheumatoid arthritis, lupus or other autoimmune diseases (SD2007-269)
• New Method To Treat Physiological Shock and Diseases of Inflammation (SD2007-128)
• New Method To Treat Septic Shock (SD2007-127)
• New Method To Reduce Complications and Hospital Stay after Radiation/Trauma/Surgery (SD2007-126)
• Small Molecule Inhibitors of the Alpha4-Paxillin Interaction (SD2007-009)
• Combination Therapy of Immunomodulatory Peptides and a Chloroquine Derivative to Treat Rheumatoid Arthritis and other Autoimmune Disorders (SD2006-256)
• Prevention and Treatment of Cytomegalovirus Infection Through Immunization with Novel CMV-derived Peptides (SD2006-074)
• Blocking Fibrin/Mac-1 Interaction as a Therapeutic Target for Multiple Sclerosis and Other Neuroinflammatory Diseases (SD2006-001)
• Gene Therapy for Osteoarthritis (SD2005-182)
• A New Approach to Treating Atherosclerosis. (SD2005-161)
• Method for Generating Unlimited Numbers of Macrophage/Dendritic Cells and Neutrophils. (SD2005-114)
• Method to Treat Autoimmune and Inflammatory Diseases (SD2005-082, SD2003-065)
• Osmotic Stress and Human Disease (SD2004-155)
• Mouse Model of Crohn’s Disease and Method to Develop Specific Therapeutics (SD2004-154)
• Lysm-Cre/IKK Beta Loxlox Mice (SD2004-141)
• Villin-Cre/IKK Beta Loxlox Mice (SD2004-140)
• Mice Lacking IKK Beta in Intestinal Epithelial Cells (SD2004-133)
• Mice Lacking IKKß in Macrophages (SD2004-132)
• Mice with a Conditional IKK Beta Loss of Function (SD2004-131)
• Mice Lacking IKK Beta in Liver Cells - Models for Acute Hepatic Failure, Hepatocellular Carcinoma and Increased Sensitivity to Insulin (SD2004-130)
• Enhancement of Th2-dependent Anti-inflammatory Response (SD2004-129)
• IKK Beta Liver Knockout Cre Mice (SD2004-120)
• Novel Matrix Metalloproteinase Inhibitors. (SD2004-102)
• Crossbred Mice: CK19 CRE X IKK Beta (Lox P) (SD2004-077)
• Novel Anti-Inflammatory Treatment by Blocking Signal Transduction Kinases in the Central Nervous System (SD2004-034)
• Irradiated Bacterial Vaccine to Induce Broad Immune Response (SD2004-B86)
• Irradiated Probiotic for Inflammatory Bowel Disease (SD2003-C32)
• Prevention of Pathogen-induced Macrophage Apoptosis (SD2003-269)
• IKK Alpha (AA) Mice (SD2003-211)
• A Practical Vaccine for Protection Against Atherosclerosis (SD2003-208)
• Reporters for the "Alternative" NF-kB Pathway (SD2003-196)
• Floxed IKKB Mice (SD2003-195)
• MEKK1 -/- Mice (SD2003-189)
• Methods for Treating Chronic Asthma (SD2003-A50)
• ST3Gal-VI Sialytransferase Inhibition for the Treatment and Prevention of Inflammation (SD2002-204)
• Ihibition of a JNK Signaling Complex as a Novel Treatment for Joint Destruction and Inflammation in Arthritis (SD2002-182)
• Dominant-Negative Kinase Adenoviral Construct for Arthritis (SD2002-169)
• P53 Knockout/DBA1 Mice as an Improved Model for Rheumatoid Arthritis (SD2002-132)
• Phase II Biologic to Treat Rheumatoid Arthritis and Other Autoimmune Diseases (SD2002-051, SD2001-901, SD2000-133, SD1999-268)
• New Uses for Inhibitors of Inosine Monophosphate Dehydrogenase (SD2002-C35)
• Treatment of Inflammatory Diseases (SD2001-213)
• A Method for Inhibiting B Cell Maturation and Antibody Production (SD2001-176)
• Inhibition of Articular Cartilage Matrix Calcification (SD2001-164)
• Novel Expression Vectors Containing Chimeric Ligand Genes Useful for Immunomodulation (SD2001-101, SD2001-102, SD2001-103, SD2001-104, SD2001-108)
• New Ligand Involved in the Transmigration of Leukocytes Across the Endothelium and Uses Therefor (SD2001-018)
• Mutations in IKKg Gene (SD2000-165)
• ISS-Receptor as a Drug Discovery Tool (SD2000-C22)
• ISS is a Chemotherapeutic Agent for Mycobacterial Infections (SD2000-B58)
• A Method to Inhibit I-Kappa-Beta Kinase, and Screen Drugs to Target Same (2000-015)
• A Method to Induce CTL Response in Immune Deficient Patients (SD1999-A77)
• Gamma-Subunit of Cytokine Responsive IkBa Kinase (IKK) Complex (1998-107)
• Selectin Inhibition: Novel Uses For An Already Approved Drug (1998-049)
• Prosaposin: Therapeutic compound for p revention and treatment of pain (SD1995-177)
• Treatment of Disorders with Shortened Red Blood Cell Survival (SD1993-B35)
• Prognostic and Diagnostic Serum Biomarker for Cancer and Inflammatory Disease (SD1992-C06 and SD1998-C98)
• Retrovirus Detection (SD1988-B08)
• Therapy for Rheumatoid Arthritis (SD1996-051)

Therapeutic Areas - Respiratory Diseases

• New drug derivatives for promoting oral delivery to the lung (SD2004-258)
• Methods for Treating Chronic Asthma (SD2003-A50)

Therapeutic Areas - Urological Diseases

• Cellular Strategies for Combating Ischemic and Other Injury to Epithelial Organs (SD2001-041)

Therapeutic Areas - Other

• High-level Expression Of Proteins From A Stably Segregating B. subtilis plasmid (SD2008-278)
• A  New Method for Treatment of Insomnia (SD2008-261)
• Genome-scale Kinetic Modeling (SD2008-180)
• Structure of Cyanobacterial Phenylalanine Ammonia Lyases (SD2007-032)
• Uncovering the Genetic Basis of Phenotypic Change (SD2007-024)
• Method of diagnosing and treating uterine fibroids (SD2006-297)
• Genome-Scale Reconstruction of Human Metabolism (SD2006-294)
• Biosynthesis of Salinosporamide A and Analogs (SD2006-203)
• Improved Treatment for Cystinosis and Neurodegenerative Disorders (SD2006-092)
• Methods for Bipolar Disorder: Diagnostic, Treatment Response Prediction and Drug Screening. (SD2006-073, SD2006-112)
• Elimination of N-glucolylneuraminic Acid from Animal Products for Human Use (SD2005-246)
• Multidentate Pyrone-Derived Chelators for Medicinal Imaging and Chelation. (SD2005-191)
• A New Approach to Treating Atherosclerosis. (SD2005-161)
• Banking Human Stem Cells from a Novel Source (SD2005-042)
• Novel Source of Human Stem Cells (SD2005-041)
• Therapy for septic shock (SD2004-263)
• Monoclonal Antibodies Immunoreactive with Lipolysaccharide Binding Protein (LBP) and Methods of Their Use (SD2004-221)
• Vaccines for Streptococcal Infection in Fish (SD2004-200)
• Vaccination and Diagnosis for Histophilus somni (formerly Haemophilus somnus) (SD2004-165)
• Mice Lacking IKK Beta in Intestinal Epithelial Cells (SD2004-133)
• Clinical Trials Management System (SD2004-082)
• Gene Therapy for Usher Syndrome Type 1B (SD2004-074)
• Treatment for Smoke Inhalation and Cyanide Poisoning. (SD2003-606)
• Screening System for Discovery of Antimicrobials, Anticancers and Crop Protection Agents (SD2003-158)
• New Treatment for Sepsis (SD2003-034)
• Transport Molecules from Dendritic Oligo-Guanidines (SD2003-144, SD2002-042)
• New Uses for Inhibitors of Inosine Monophosphate Dehydrogenase (SD2002-C35)
• Multi-Potent Central Nervous System (CNS) Stem Cells (SD2001-052)
• Cellular Strategies for Combating Ischemic and Other Injury to Epithelial Organs (SD2001-041)
• A New Anti-Coagulant (2000-035)
• Disease Treatments Using Multimeric TNFSF Ligands (SD1999-003)
• New Approach to Tissue Repair (SD1997-108)
• Prosaposin: Therapeutic compound for p revention and treatment of pain (SD1995-177)
• Transcription Factor for the Regulation of Skin and Hair Development (SD1993-A27)
• Treatment of Disorders with Shortened Red Blood Cell Survival (SD1993-B35)

Stem Cells

• Transplantation of Human Neural Cells for Treatment of Neurodegenerative Conditions (SD2008-210)
• In Vivo Model for Hematopoietic and Cancer Stem Cell Development (SD2007-241)
• Simple Method for Deriving Germ Cells, Male Gametes and Supporting Sertoli-like Cells from Human Embryonic Stem Cells (SD2007-179)
• A Novel Marker of Hematopoietic Stem Cells (SD2007-119)
• Therapeutics and Diagnostics for Hematopoietic and Cancer Stem Cell (SD2007-099)
• Novel Screen for Agents affecting Normal and Malignant Blood Cell Development (SD2007-090)
• Elimination of N-glucolylneuraminic Acid from Animal Products for Human Use (SD2005-246)
• Banking Human Stem Cells from a Novel Source (SD2005-042)
• Novel Source of Human Stem Cells (SD2005-041)
• Multi-Potent Central Nervous System (CNS) Stem Cells (SD2001-052)

New Chemical Entities, Drug Leads

• TNF-alpha inhibitor to suppress infalmmation without suppessing the innate immune response (SD2008-129)
• Comprehensive Pharmacogenetic Approach to the Diagnosis and Treatment of Cancer (cancer bundle/SD2007-cancer)
• Compounds Targeting Misregulated Protein Kinases (SD2008-009)
• Structure of Cyanobacterial Phenylalanine Ammonia Lyases (SD2007-032)
• Biosynthesis of Salinosporamide A and Analogs (SD2006-203)
• Lead Compounds for Diagnosis and Therapy of Alzheimer's Disease (SD2006-105)
• Natural Products for Cancer Therapeutics (SD2006-079)
• Novel Alkoxyalkyl Phosphate Derivatives of Nucleoside Phosphonates with Antiviral Activity. (SD2005-175)
• Apoptosis Inhibitors (SD2005-E50)
• Oligonucleotides for the Treatment of Cancer and Autoimmune Diseases (SD2004-013)
• Isolates from Marine Invertabrates Compound Library for Drug Screening (SD2003-039)

Delivery Systems

• Composition and Methods for Sealing Large Wound Sites and Bleeding Control (SD2008-264)
• Scalable, Inexpensive Method to Make Hollow Nanoparticles for Life Science Applications (SD2008-016)
• Spinal Multi-segmental Cell and Drug Delivery System (SD2007-267)
• Method for manipulating and heating of discrete droplets using magnetic particles derived from porous silicon (SD2006-176)
• pH-“Tunable” Nano-particle Drug Delivery System (SD2006-140)
• In Vitro Method to Improve Transfection Efficiency with In Vivo Applicability (SD2005-251)
• Optimizing Expression of Recombinant Protein in Mammalian Cells (SD2005-186)
• New Method for Promoting Nerve Regeneration (SD2005-155)
• Porous Photonic Crystals for Intraocular Drug Delivery (SD2005-088)
• Biological Applications of "Smart Dust" - Porous Silicon Photonic Crystals (SD2005-038, SD2005-044)
• New drug derivatives for promoting oral delivery to the lung (SD2004-258)
• Transport Molecules from Dendritic Oligo-Guanidines (SD2003-144, SD2002-042)
• Lipids for Local Eye Therapy for Diseases (SD2003-113)
• Use of Guaninidination to Modify Natural products as Cellular Delivery Vehicles (SD2002-135)
• A New Family of Anti-Viral Agents and Related High-Throughput Screens (SD2000-074)
• A Macromolecular Carrier for Medical Imaging and Diagnostics (SD1998-088)
• Novel, Virus-Independent In Vivo Gene Therapy Approach (SD1998-035)
• Enhanced Transfection Efficiency in the Presence of Serum (SD1998-033)
• Enhancement of Gene Transfer Using a Viral Protein Preparation (SD1997-093)
• Reagents And Process For Improved Potency Retrovirus Preparations For Efficient Production Of Gene Therapy Agents (SD1997-049)
• Method for Production of Neuroblasts (SD1992-B16)
• Mammalian Artificial Chromosome: Utilization for Gene Transfer (SD1996-015)
• Regulatable retrovirus system for genetic modification of cells (SD1996-B05)
• Human Methods and Use of CNS Cell Lines (SD1998-A34)

Diagnostics

• Clinical Immunoassays to Determine Concentration of Monoclonal Antibodies (SD2008-226)
• Predictive Biomarkers for Metastatic Potential in Breast Cancer (SD2008-084)
• Comprehensive Pharmacogenetic Approach to the Diagnosis and Treatment of Cancer (cancer bundle/SD2007-cancer)
• A 10X Improvement in MR Imaging of Weak Oscillating Magnetic Fields -Multiple Alternating Balanced Steady States (MABSS) (SD2008-019)
• A New Approach to Medical Diagnostics and Therapeutics (SD2007-320)
• Novel Methods to Predict New Cardiovascular Events by Measuring Oxidized Phospholipids (OxPL), Lipoprotein (a) and Lipoprotein-Associated Phospholipase A2 Mass and Activity (Lp-PLA2) and Novel High-Throughput Assay to Quantitate Lp-PLA2 on Lipoprotein (a) and Apolipprotein B-100 Particles to Determine Cardiovascular Risk (SD2007-261)
• Fast Correction of Inhomogeneous Magnetic Field Distortion in MRI (SD2007-217)
• Annular Laser Trap for Cell Sorting and Behavior Analysis (SD2007-192)
• Microfluidic Flow Cytometry (SD2007-097)
• New Derivatives of Pyrone, Hydroxypyridinone, and Hydroxypyridinethione (SD2007-058)
• Method for MRI-based Magnetoencephalography Possessing High Spatial
  Resolution a.k.a. “Phase Accumulation at Steady State (PASS)” (SD2007-035)
• Methods for High Sensitivity Detection of Deletions from Genomic DNA (SD2006-249)
• Biomarker for Neurodegenerative and Demyelinating Disease (SD2006-086)
• Methods for Bipolar Disorder: Diagnostic, Treatment Response Prediction and Drug Screening. (SD2006-073, SD2006-112)
• Method to Image and Detect Islet Beta Cells Using Cell-surface Proteins (SD2005-224)
• Treatment and Diagnosis Of Chronic Lymphocytic Leukemia (CLL), Breast Cancer, And Other Cancers Through Use of a Monoclonal Antibody (SD2005-212)
• Multidentate Pyrone-Derived Chelators for Medicinal Imaging and Chelation. (SD2005-191)
• Chemical Sensing by RIFTS-Reflective Interferometric Fourier-Transform Spectroscopy: A Robust, Self-Compensating Method for Label-Free Detection of Biomolecules (SD2005-179)
• Detection and Validation of Biomarkers for Neuropsychiatric Disorders (SD2005-141)
• Novel Cancer and Inflammation Detection Using Medical Imaging (SD2005-138)
• Novel Biosensors for the diagnoses of Cervical, Breast, and other cancers (SD2005-089)
• Novel Markers for the Treatment and Diagnosis of Chronic Lumphocytic Leukemia (CLL) (SD2005-082)
• Biological Applications of "Smart Dust" - Porous Silicon Photonic Crystals (SD2005-038, SD2005-044)
• A Novel Index of Assessing Atherosclerosis Regression and Plaque Stabilization (SD2005-037)
• Detecting Gene Expression With Ultrasound (SD2005-011)
• A Method of Ultrasound Signal Augmentation (SD2005-010)
• A Method to Detect and Treat Localized Abnormalities (SD2004-251)
• Method to assess anxiolytic properties of therapeutic agents (SD2004-172)
• Vaccination and Diagnosis for Histophilus somni (formerly Haemophilus somnus) (SD2004-165)
• Portable Hand Held Alveolar Oxygen and Carbon Dioxide Meter (SD2004-087)
• Vaccines and Diagnostics Using the Native Capsule of Group B Streptococcus (SD2004-027)
• Diagnostic Markers for Kawasaki Disease (SD2004-014)
• Means to detect, treat and prevent sensorineural hearing loss (SD2004-004)
• Regulating genes in the COX-2 pathway for colon cancer (SD2003-261)
• Genetic Testing and Treatment for Alpers Syndrome (SD2003-221)
• Cell Surface Dietary Marker in Cancer and Immune Disease (SD2003-141, SD2003-142)
• Transport Molecules from Dendritic Oligo-Guanidines (SD2003-144, SD2002-042)
• Diagnosis of HNPCC (SD2003-064)
• Digital Molecular Sensor (SD2003-060)
• Multiparallel Three Dimensional Optical Microscopy System (SD2003-056)
• Novel Markers and Gene Targets useful for the Diagnosis and Suppression of Metastasis (SD2002-005)
• Diagnostic and Analytical Applications for Bovine and Human Anti-trichomonad Monoclonal Antibodies (SD2000-131)
• Gene Targets for Neuro-psychiatric Disorders (SD2000-126 & SD2000-094)
• Assessing Risk for Arterial Calcification (SD1999-C79)
• A Novel Blood/Urine Test for the Detection of Acute Venous Thromboembolic Disease (1999-114)
• Diagnostics for Diseases of Abnormal Protein Glycosylation (SD1999-001)
• Diagnosis of Cancers with Metastatic Potential (SD1998-D00)
• Method for Early Diagnosis and Determination of Prognosis in Cancer (SD1998-B84)
• Diagnostic Imaging of Lymph Structures (SD1998-120)
• Novel, Virus-Independent In Vivo Gene Therapy Approach (SD1998-035)
• Enhanced Transfection Efficiency in the Presence of Serum (SD1998-033)
• Hydrogen Peroxide Sensing Electrode (SD1998-014)
• Enhanced Transfection Efficiency in the Presence of Serum (SD1997-093)
• A Mammalian Artificial Chromosome: Utilization For Gene Transfer (SD1996-015)
• Mycothiol-specific Antibodies and their use for Diagnosis of Mycobacteria (SD1996-092)
• Novel Reagents for Improved Clinical Diagnosis and Assessment of Atherosclerosis (SD1996-045)
• Assay of GTP/GDP Bound to RAS and Other G Proteins (SD1994-B09)
• Treatment of Disorders with Shortened Red Blood Cell Survival (SD1993-B35)
• Method for Selective Methionine Starvation of Malignant Cells (SD1992-C83)
• Prognostic and Diagnostic Serum Biomarker for Cancer and Inflammatory Disease (SD1992-C06 and SD1998-C98)
• Methods for the Detection of BCR-ABL and Abnormal ABL Proteins in Leukemia Patients (SD1990-C65)

Medical Devices

• Novel Instrument To Surgically Treat Fecal Incontinence, Urinary Incontinence, Uterine Prolapse, And Vaginal Laxity (SD2009-007)
• Composition and Methods for Sealing Large Wound Sites and Bleeding Control (SD2008-264)
• Clinical Immunoassays to Determine Concentration of Monoclonal Antibodies (SD2008-226)
• Novel Method for Improving Ultrasound (US) Transducers (SD2008-200)
• Calorie Pacer (SD2008-160)
• Non-contact Biopotential Sensor (SD2008-143)
• A Duplexed Multiline Multiphoton Microscope (SD2008-074)
• Adaptive Eyeglass Lens for Correction of Presbyopia (SD2008-015)
• Universal Toy Adaptor for Children with Disabilities (SD2007-314)
• Spinal Multi-segmental Cell and Drug Delivery System (SD2007-267)
• Comfortable Nasal Lavage (SD2007-207)
• Intra-Cavity Miniature Portable Visualization System For Surgery (SD2007-197)
• Ultrashort Echo Time (UTE) Spectroscopic Imaging of Tissues with Short Transverse Relaxation Time (T2) (SD2007-131)
• Ultrasono-Manometry Esophageal Function Assessment (SD2007-011)
• PNEUFLOW™: A Device for Increasing Tissue Blood Flow (SD2006-185)
• FlexoPred: New Tool For Protein Engineering (SD2006-123)
• Method for Treatment of Post-Shock Inflammation (SD2006-068)
• Novel Gene Gun (SD2004-207)
• Real-Time Prediction and Prevention of Seizures (SD2004-091)
• Mental Improvement Through Magnetic Stimulation (SD2004-090)
• Portable Hand Held Alveolar Oxygen and Carbon Dioxide Meter (SD2004-087)
• NoScar ThinFilm: A biocompatible polymer film for post-surgical scar reduction (SD2004-028)
• Hyperecho Diffusion-Weighted Magnetic Resonance Imaging (SD2003-177)
• Multiparallel Three Dimensional Optical Microscopy System (SD2003-056)
• Laser-Based Method to Induce and Image Cortical Microstrokes in-vivo for Preclinical Analyses (SD2003-021)
• Improved Perfusion Imaging Using MRI (SD2001-175)
• New Method for Analyzing MRI Diffusion Data (SD2001-084)
• Lipophilic Fluorescent Probes for the Study of Cell Membrane Properties (SD2000-145)
• Method to Enhance Microhardness and Fretting Resistance of Implant Prosthesis (2000-089)
• Improved, Real-time brain Computer Interface Systems (SD1999-002)
• Hydrogen Peroxide Sensing Electrode (SD1998-014)
• Improved Intubation/Extubation Device (SD1992-A33)
• Control of Skeletal Muscle Fatigue During Electrical Stimulation (SD1993-303)
• Adaptive Closed Loop Electrical Stimulation of Muscles (SD1985-235)

Research Reagents

Antibodies
Cell Lines
Mice
Nucleic Acids
Other

Research Reagents developed at UCSD are listed on the TechTIPS website at: Research Reagents and Cell Lines

Research Tools - Screening Assays

• Fluorescent Proteins with Increased Photostability (SD2008-123)
• A Method to Measure Neurotransmitters In Vivo (SD2007-283)
• In Vivo Model for Hematopoietic and Cancer Stem Cell Development (SD2007-241)
• Moldable polycarbonate based biosensors (SD2007-167)
• Mechanism of Pain Relief In Diabetes By Prosaptide TX14(A) (SD2007-099)
• Novel Screen for Agents affecting Normal and Malignant Blood Cell Development (SD2007-090)
• Method for Identifying Drug Targets Using Sequence Data (SD2007-022)
• Zebrafish Model for Atherosclerosis (SD2007-014)
• A Modulated Dielectrophoretic System for Ex-Vivo Diagnostics, Drug Monitoring and Disease Management (SD2006-207)
• Compounds and Screens for Therapeutics against Tuberculosis and other Mycobacterial Infections (SD2006-197)
• A high throughput assay to identify drug candidates targeting protein kinase a in non-atp binding sites (SD2006-160)
• Screening Assay for Compounds to Treat and Diagnose Alzheimer's Disease (SD2005-262)
• Chemical Sensing by RIFTS-Reflective Interferometric Fourier-Transform Spectroscopy: A Robust, Self-Compensating Method for Label-Free Detection of Biomolecules (SD2005-179)
• Mouse Model for Macular Degeneration (SD2005-163)
• A Simple Quantitative Method To Measure Cellular Secretion (SD2005-156)
• Acid-Reactive Antibodies for Therapy and Research Applications (SD2005-142)
• Fluorescent Nucleoside Analogs that Mimic Naturally Occurring Nucleosides (SD2005-116)
• Biological Applications of "Smart Dust" - Porous Silicon Photonic Crystals (SD2005-038, SD2005-044)
• Method to assess anxiolytic properties of therapeutic agents (SD2004-172)
• Expression of Human CYP1A1 in Mice (SD2004-162)
• Specific Assay for the HIV-induced CD4 Down-modulation for the Screening of anti-HIV Drugs (SD2004-066)
• “Smart Dust” – Porous Silicon Photonic Crystals (SD2004-032)
• Apparatus Enabling Microfluidic Connectivity for High Throughput Screening (SD2004-001)
• Complex Optical Encoding of Porous Silicon Photonic Crystals (SD2003-214)
• Screening Method to Discover a New Candidate Therapeutic for Type II Diabetes (SD2003-202)
• Method for Generating a Progenitor Population from Postnatal Hearts (SD2003-140)
• A Method for Screening for Therapeutics for Neuropsychiatric Disorders Using a Norway Rat Model (SD2003-091)
• Novel Animal Model and Screening System for Anti-Psychotic Drugs (SD2003-089, SD2003-090)
• A Novel Genetic Method for Generating Gain-of-Function Mutations (SD2001-107)
• A Method to Inhibit I-Kappa-Beta Kinase, and Screen Drugs to Target Same (2000-015)
• Complementary Screens for the Development of Tuberculosis Drugs and Vaccines (1999-156)
• Murine Cell lines for studing innate immunity and myeloid progenitors (SD1999-053)
• Rapid Diagnostic Assay for Cytolytic T-Cell Killing of Target Cells (SD1998-062)
• Novel Screening Method for Drugs that Modulate Transcription (SD1997-102)
• Device for Detection of Organic Compounds, Ions and Other Molecular Species by Optical Interference in a Porous Silicon Layer (1997-064)
• Assay of GTP/GDP Bound to RAS and Other G Proteins (SD1994-B09)
• Prognostic and Diagnostic Serum Biomarker for Cancer and Inflammatory Disease (SD1992-C06 and SD1998-C98)
• Retrovirus Detection (SD1988-B08)

Research Tools - Genomics and Related DNA / RNA Methods

• Genome-scale Kinetic Modeling (SD2008-180)
• Predictive Biomarkers for Metastatic Potential in Breast Cancer (SD2008-084)
• A New Approach to Medical Diagnostics and Therapeutics (SD2007-320)
• TimeSTAMP: Drug Controlled Molecular Tags for Visualizing Protein Turnover (SD2007-039)
• Uncovering the Genetic Basis of Phenotypic Change (SD2007-024)
• Genome-Scale Reconstruction of Human Metabolism (SD2006-294)
• Methods for High Sensitivity Detection of Deletions from Genomic DNA (SD2006-249)
• DNA Sequencing with Single Nucleotide Resolution via Nanopores (SD2006-220)
• Method and System for Rapid Construction and Screening of Functional, Tagged, Fusion Proteins (SD2006-094)
• In Vitro Method to Improve Transfection Efficiency with In Vivo Applicability (SD2005-251)
• Chemical Sensing by RIFTS-Reflective Interferometric Fourier-Transform Spectroscopy: A Robust, Self-Compensating Method for Label-Free Detection of Biomolecules (SD2005-179)
• Fluorscent Nucleoside Analogs that Mimic Naturally Occurring Nucleosides (SD2005-116)
• "Smart Dust” – Porous Silicon Photonic Crystals (SD2004-032)
• Complex Optical Encoding of Porous Silicon Photonic Crystals (SD2003-214)
• Determination of Protein Size (SD2003-182)
• Method for Automated Injection of drosophila Embryos (SD2002-167)
• Novel Recyclable Silylation Reagent for Use in Generating Protecting Groups in Large-Scale Oligonucleotide Manufacture (SD2002-164)
• Laser-Mediated Automated Tissue Sectioning and in situ Localization of Proteins and mRNA (SD2002-116)
• Whole-Proteome Interaction Mining: Computational Approach (SD2002-033)
• Novel Single Nucleotide Polymorphisms (SNPs) Associated with Hypertension (SD2001-215)
• Method for Predicting Protein Binding from Primary Structure Data (SD2001-034)
• Mining Genes from the Ocean (SD2001-027)
• Automated Cell and Tissue Extraction and Solid Phase Capture Device (SD2001-007)
• Electrochemical DNA Sequencing (SD2000-168 and SD2001-228)
• Time-saving Method for Solid Phase Isolation of Proteins, Nucleic Acids and Other Macromolecules (SD1998-108)
• Device for Detection of Organic Compounds, Ions and Other Molecular Species by Optical Interference in a Porous Silicon Layer (1997-064)
• Recombinant Luciferase Gene, Luciferase Fusion Proteins and Methods of Use (1984-C05)

Research Tools - Proteomics and Related Protein Methods

• Genome-scale Kinetic Modeling (SD2008-180)
• Genetically Encoded Singlet Oxygen Sensor
• New Tools for Protein Functional Site Characterization (SD2007-112)
• Method for Identifying Drug Targets Using Sequence Data (SD2007-022)
• Method for Identification of Peptides and Post-Translational Modifications (SD2006-162 and SD2006-817)
• Genome-Scale Reconstruction of Human Metabolism (SD2006-294)
• Active Microelectronic Array for Massively Parallel Peptide Synthesis & Binding Constant Analysis (SD2006-208)
• In vivo Protein Labeling (SD2005-272)
• Chemical Sensing by RIFTS-Reflective Interferometric Fourier-Transform Spectroscopy: A Robust, Self-Compensating Method for Label-Free Detection of Biomolecules (SD2005-179)
• Biological Applications of "Smart Dust" - Porous Silicon Photonic Crystals (SD2005-038, SD2005-044)
• Predicted Ligands for Binding Orphan G-Protein-Coupled Receptors and Method Therefore (SD2004-148)
• “Smart Dust” – Porous Silicon Photonic Crystals (SD2004-032)
• Chemical Tools for Analysis and Manipulation of Enzymes in Biosynthetic Proteomes (SD2003-226)
• Complex Optical Encoding of Porous Silicon Photonic Crystals (SD2003-214)
• Determination of Protein Size (SD2003-182)
• Digital Molecular Sensor (SD2003-060)
• The Use Of Deuterium Exchange-Mass Spectrometry To Enhance Large-Scale Protein Crystallographic Structure Determination (SD2002-157)
• Laser-Mediated Automated Tissue Sectioning and in situ Localization of Proteins and mRNA (SD2002-116)
• Whole-Proteome Interaction Mining: Computational Approach (SD2002-033)
• CE-Combinatorial Extension (SD2001-155)
• Method for Predicting Protein Binding from Primary Structure Data (SD2001-034)