Prior to joining UCSD, Bill was employed for five years at a small biomedical device start-up first based in Florida, then in Orange County, California, where he held positions of increasing responsibility with duties that were increasingly cross-functional between business and R&D. Bill's work at the company resulted in six issued US patents, four issued non-US patents, and other patents pending in the US, Europe, Japan, and Hong-Kong

Over the years he has delivered talks at meetings of the American Physical Society, the American Nuclear Society, the Society for Industrial and Applied Mathematics, the International Society for Analytical Cytology, the Association for Women in Science, and the National Association of College and University Attorneys.